GB9828074D0 - Therapeutically useful compounds - Google Patents

Therapeutically useful compounds

Info

Publication number
GB9828074D0
GB9828074D0 GBGB9828074.6A GB9828074A GB9828074D0 GB 9828074 D0 GB9828074 D0 GB 9828074D0 GB 9828074 A GB9828074 A GB 9828074A GB 9828074 D0 GB9828074 D0 GB 9828074D0
Authority
GB
United Kingdom
Prior art keywords
therapeutically useful
useful compounds
compounds
therapeutically
useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB9828074.6A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Priority to GBGB9828074.6A priority Critical patent/GB9828074D0/en
Publication of GB9828074D0 publication Critical patent/GB9828074D0/en
Priority to ARP990106429A priority patent/AR023727A1/es
Priority to CO99078241A priority patent/CO5170533A1/es
Priority to HK02100145.2A priority patent/HK1038744A1/zh
Priority to DE69919580T priority patent/DE69919580T2/de
Priority to US09/868,395 priority patent/US6867192B1/en
Priority to ES99964583T priority patent/ES2226488T3/es
Priority to KR1020017007579A priority patent/KR20010101258A/ko
Priority to PCT/EP1999/010000 priority patent/WO2000037444A1/en
Priority to CZ20012209A priority patent/CZ20012209A3/cs
Priority to CA002355630A priority patent/CA2355630A1/en
Priority to JP2000589516A priority patent/JP4431282B2/ja
Priority to PL99348059A priority patent/PL348059A1/xx
Priority to BR9916282-2A priority patent/BR9916282A/pt
Priority to HU0104867A priority patent/HUP0104867A3/hu
Priority to AU30391/00A priority patent/AU760169B2/en
Priority to NZ511478A priority patent/NZ511478A/en
Priority to IL14290899A priority patent/IL142908A0/xx
Priority to TR2001/01709T priority patent/TR200101709T2/xx
Priority to CN99814654A priority patent/CN1330637A/zh
Priority to AT99964583T priority patent/ATE273954T1/de
Priority to PE1999001274A priority patent/PE20001387A1/es
Priority to EP99964583A priority patent/EP1140837B1/en
Priority to GT199900217A priority patent/GT199900217A/es
Priority to ZA200103948A priority patent/ZA200103948B/en
Priority to NO20012995A priority patent/NO20012995L/no
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/205—Radicals derived from carbonic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/40—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06043—Leu-amino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GBGB9828074.6A 1998-12-18 1998-12-18 Therapeutically useful compounds Ceased GB9828074D0 (en)

Priority Applications (26)

Application Number Priority Date Filing Date Title
GBGB9828074.6A GB9828074D0 (en) 1998-12-18 1998-12-18 Therapeutically useful compounds
ARP990106429A AR023727A1 (es) 1998-12-18 1999-12-15 Compuestos empleados en el tratamiento de padecimientos inflamatorios
CO99078241A CO5170533A1 (es) 1998-12-18 1999-12-15 Derivados del acido fenil propanoico empleados en el tratami ento de padecimientos inflamatorios
EP99964583A EP1140837B1 (en) 1998-12-18 1999-12-16 Compounds useful in the treatment of inflammatory diseases
PL99348059A PL348059A1 (en) 1998-12-18 1999-12-16 Compounds useful in the treatment of inflammatory diseases
HU0104867A HUP0104867A3 (en) 1998-12-18 1999-12-16 Heterocyclic compounds useful in the treatment of inflammatory diseases, process for their preparation, pharmaceutical compositions comprising thereof and their use
US09/868,395 US6867192B1 (en) 1998-12-18 1999-12-16 Compounds useful in the treatment of inflammatory diseases
ES99964583T ES2226488T3 (es) 1998-12-18 1999-12-16 Compuestos utiles en el tratamiento de enfermedades inflamatorias.
KR1020017007579A KR20010101258A (ko) 1998-12-18 1999-12-16 염증 질환 치료용 화합물
PCT/EP1999/010000 WO2000037444A1 (en) 1998-12-18 1999-12-16 Compounds useful in the treatment of inflammatory diseases
CZ20012209A CZ20012209A3 (cs) 1998-12-18 1999-12-16 Sloučeniny s protizánětlivým účinkem
CA002355630A CA2355630A1 (en) 1998-12-18 1999-12-16 Compounds useful in the treatment of inflammatory diseases
JP2000589516A JP4431282B2 (ja) 1998-12-18 1999-12-16 炎症性疾患の治療に有用な化合物
HK02100145.2A HK1038744A1 (zh) 1998-12-18 1999-12-16 用於治療炎性疾病的化合物
BR9916282-2A BR9916282A (pt) 1998-12-18 1999-12-16 Composto, uso de um um composto e método de tratamento
DE69919580T DE69919580T2 (de) 1998-12-18 1999-12-16 Verbindungen zur anwendung bei der behandlung entzündlicher erkrankungen
AU30391/00A AU760169B2 (en) 1998-12-18 1999-12-16 Compounds useful in the treatment of inflammatory diseases
NZ511478A NZ511478A (en) 1998-12-18 1999-12-16 Compounds useful in the treatment of inflammatory diseases
IL14290899A IL142908A0 (en) 1998-12-18 1999-12-16 Compounds useful in the treatment of inflammatory diseases
TR2001/01709T TR200101709T2 (tr) 1998-12-18 1999-12-16 İltihabik hastalıkların tedavisinde yararlı olan bileşikler
CN99814654A CN1330637A (zh) 1998-12-18 1999-12-16 用于治疗炎性疾病的化合物
AT99964583T ATE273954T1 (de) 1998-12-18 1999-12-16 Verbindungen zur anwendung bei der behandlung entzündlicher erkrankungen
PE1999001274A PE20001387A1 (es) 1998-12-18 1999-12-16 Compuestos empleados en el tratamiento de padecimientos inflamatorios
GT199900217A GT199900217A (es) 1998-12-18 1999-12-17 Compuestos empleados en el tratamiento de padecimientos inflamatorios.
ZA200103948A ZA200103948B (en) 1998-12-18 2001-05-15 Compounds useful in the treatment of inflammatory diseases.
NO20012995A NO20012995L (no) 1998-12-18 2001-06-15 Forbindelser nyttige for behandling av inflammatoriske sykdommer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9828074.6A GB9828074D0 (en) 1998-12-18 1998-12-18 Therapeutically useful compounds

Publications (1)

Publication Number Publication Date
GB9828074D0 true GB9828074D0 (en) 1999-02-17

Family

ID=10844608

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB9828074.6A Ceased GB9828074D0 (en) 1998-12-18 1998-12-18 Therapeutically useful compounds

Country Status (26)

Country Link
US (1) US6867192B1 (enExample)
EP (1) EP1140837B1 (enExample)
JP (1) JP4431282B2 (enExample)
KR (1) KR20010101258A (enExample)
CN (1) CN1330637A (enExample)
AR (1) AR023727A1 (enExample)
AT (1) ATE273954T1 (enExample)
AU (1) AU760169B2 (enExample)
BR (1) BR9916282A (enExample)
CA (1) CA2355630A1 (enExample)
CO (1) CO5170533A1 (enExample)
CZ (1) CZ20012209A3 (enExample)
DE (1) DE69919580T2 (enExample)
ES (1) ES2226488T3 (enExample)
GB (1) GB9828074D0 (enExample)
GT (1) GT199900217A (enExample)
HK (1) HK1038744A1 (enExample)
HU (1) HUP0104867A3 (enExample)
IL (1) IL142908A0 (enExample)
NO (1) NO20012995L (enExample)
NZ (1) NZ511478A (enExample)
PE (1) PE20001387A1 (enExample)
PL (1) PL348059A1 (enExample)
TR (1) TR200101709T2 (enExample)
WO (1) WO2000037444A1 (enExample)
ZA (1) ZA200103948B (enExample)

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WO2001051487A1 (en) 1999-12-28 2001-07-19 Pfizer Products Inc. Non-peptidyl inhibitors of vla-4 dependent cell binding useful in treating inflammatory, autoimmune, and respiratory diseases
GB0014881D0 (en) * 2000-06-16 2000-08-09 Glaxo Group Ltd Pharmaceutical aerosol formulation
GB0014869D0 (en) * 2000-06-16 2000-08-09 Glaxo Group Ltd Novel pharmaceutical formulation
GB0014892D0 (en) * 2000-06-16 2000-08-09 Glaxo Group Ltd Novel pharmaceutical formulation
GB0014947D0 (en) * 2000-06-16 2000-08-09 Glaxo Group Ltd Novel pharmaceutical formulation
GB0014851D0 (en) * 2000-06-16 2000-08-09 Glaxo Group Ltd Novel pharmaceutical formulation
GB0014849D0 (en) * 2000-06-16 2000-08-09 Glaxo Group Ltd Pharmaceutical aerosol formulation
GB0014883D0 (en) * 2000-06-16 2000-08-09 Glaxo Group Ltd Novel pharmaceutical formulation
GB0127423D0 (en) * 2001-11-15 2002-01-09 Glaxo Group Ltd Process
GB0218630D0 (en) 2002-08-10 2002-09-18 Tanabe Seiyaku Co Novel compounds
WO2004103967A2 (en) 2003-05-20 2004-12-02 Genentech, Inc. Thiocarbamate inhibitors of alpha-4 integrins
KR20070029733A (ko) 2004-06-04 2007-03-14 제넨테크, 인크. 다발성 경화증의 치료 방법
US8310442B2 (en) 2005-02-23 2012-11-13 Pixtronix, Inc. Circuits for controlling display apparatus
US9261694B2 (en) 2005-02-23 2016-02-16 Pixtronix, Inc. Display apparatus and methods for manufacture thereof
US7999994B2 (en) 2005-02-23 2011-08-16 Pixtronix, Inc. Display apparatus and methods for manufacture thereof
US8159428B2 (en) 2005-02-23 2012-04-17 Pixtronix, Inc. Display methods and apparatus
US20070205969A1 (en) 2005-02-23 2007-09-06 Pixtronix, Incorporated Direct-view MEMS display devices and methods for generating images thereon
US9158106B2 (en) 2005-02-23 2015-10-13 Pixtronix, Inc. Display methods and apparatus
US8519945B2 (en) 2006-01-06 2013-08-27 Pixtronix, Inc. Circuits for controlling display apparatus
US9229222B2 (en) 2005-02-23 2016-01-05 Pixtronix, Inc. Alignment methods in fluid-filled MEMS displays
US8482496B2 (en) 2006-01-06 2013-07-09 Pixtronix, Inc. Circuits for controlling MEMS display apparatus on a transparent substrate
US7742016B2 (en) 2005-02-23 2010-06-22 Pixtronix, Incorporated Display methods and apparatus
US9082353B2 (en) 2010-01-05 2015-07-14 Pixtronix, Inc. Circuits for controlling display apparatus
MY149159A (en) 2005-11-15 2013-07-31 Hoffmann La Roche Method for treating joint damage
US8526096B2 (en) 2006-02-23 2013-09-03 Pixtronix, Inc. Mechanical light modulators with stressed beams
US9176318B2 (en) * 2007-05-18 2015-11-03 Pixtronix, Inc. Methods for manufacturing fluid-filled MEMS displays
TW201438738A (zh) 2008-09-16 2014-10-16 Genentech Inc 治療進展型多發性硬化症之方法
US8169679B2 (en) 2008-10-27 2012-05-01 Pixtronix, Inc. MEMS anchors
WO2010075249A2 (en) 2008-12-22 2010-07-01 Genentech, Inc. A method for treating rheumatoid arthritis with b-cell antagonists
KR101659642B1 (ko) 2010-02-02 2016-09-26 픽스트로닉스 인코포레이티드 디스플레이 장치를 제어하기 위한 회로
WO2011097252A2 (en) 2010-02-02 2011-08-11 Pixtronix, Inc. Methods for manufacturing cold seal fluid-filled display apparatus
WO2013101771A2 (en) 2011-12-30 2013-07-04 Genentech, Inc. Compositions and method for treating autoimmune diseases
AR091305A1 (es) 2012-01-31 2015-01-28 Genentech Inc ANTICUERPOS ANTI-IgE Y SUS METODOS DE USO
US9134552B2 (en) 2013-03-13 2015-09-15 Pixtronix, Inc. Display apparatus with narrow gap electrostatic actuators
WO2015181837A2 (en) * 2014-05-30 2015-12-03 Sphaera Pharma Pvt. Ltd. Novel compounds as anti-tubercular agents
PL3319639T3 (pl) * 2015-07-08 2021-03-08 Axerovision, Inc. Kompozycje farmaceutyczne zawierające antagonistę integryny alfa4 do stosowania w leczeniu stanów zapalnych oka
HRP20250052T1 (hr) 2015-10-06 2025-03-14 F. Hoffmann - La Roche Ag Postupak liječenja multiple skleroze
HRP20220479T1 (hr) * 2016-06-01 2022-05-27 Athira Pharma, Inc. Spojevi
CN109722455B (zh) * 2017-10-31 2022-03-11 中国科学院天津工业生物技术研究所 微生物发酵生产谷内酯的方法、工程菌及应用
WO2019246455A1 (en) 2018-06-20 2019-12-26 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with an integrin inhibitor
ES3003232T3 (en) 2018-10-30 2025-03-10 Gilead Sciences Inc Compounds for inhibition of alpha4beta7 integrin
ES2987796T3 (es) 2018-10-30 2024-11-18 Gilead Sciences Inc Derivados de N-benzoil-fenilalanina como inhibidores de la integrina alfa4beta7 para el tratamiento de enfermedades inflamatorias
CN112969687B (zh) 2018-10-30 2024-08-23 吉利德科学公司 作为α4β7整合素抑制剂的喹啉衍生物
CA3114240C (en) 2018-10-30 2023-09-05 Gilead Sciences, Inc. Imidazopyridine derivatives as alpha4beta7 integrin inhibitors
CN114222730B (zh) 2019-08-14 2024-09-10 吉利德科学公司 用于抑制α4β7整合素的化合物
JP2023546915A (ja) * 2020-10-21 2023-11-08 アズーラ オフサルミックス エルティーディー． 眼障害を処置するための化合物および方法

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DE1593858A1 (de) 1967-03-02 1970-10-29 Hoechst Ag Verfahren zur Herstellung tyrosinhaltiger Peptide und deren Derivaten
US4105602A (en) 1975-02-10 1978-08-08 Armour Pharmaceutical Company Synthesis of peptides with parathyroid hormone activity
US6248713B1 (en) 1995-07-11 2001-06-19 Biogen, Inc. Cell adhesion inhibitors
AU728435B2 (en) 1997-05-29 2001-01-11 Merck & Co., Inc. Sulfonamides as cell adhesion inhibitors
ES2257808T3 (es) 1997-05-29 2006-08-01 MERCK & CO., INC. (A NEW JERSEY CORP.) Acidos biarilalcanoicos como inhibidores de adhesion celular.
CA2291778A1 (en) 1997-05-29 1998-12-03 Merck & Co., Inc. Heterocyclic amide compounds as cell adhesion inhibitors
ATE256699T1 (de) * 1997-05-30 2004-01-15 Celltech Therapeutics Ltd Entzündungshemmende tyrosin-derivate

Also Published As

Publication number Publication date
HUP0104867A3 (en) 2002-06-28
ATE273954T1 (de) 2004-09-15
US6867192B1 (en) 2005-03-15
ES2226488T3 (es) 2005-03-16
PL348059A1 (en) 2002-05-06
CZ20012209A3 (cs) 2001-09-12
GT199900217A (es) 2001-06-09
HUP0104867A2 (hu) 2002-04-29
NO20012995D0 (no) 2001-06-15
PE20001387A1 (es) 2000-12-22
EP1140837B1 (en) 2004-08-18
BR9916282A (pt) 2001-10-02
JP4431282B2 (ja) 2010-03-10
CA2355630A1 (en) 2000-06-29
AR023727A1 (es) 2002-09-04
IL142908A0 (en) 2002-04-21
AU3039100A (en) 2000-07-12
EP1140837A1 (en) 2001-10-10
WO2000037444A1 (en) 2000-06-29
CO5170533A1 (es) 2002-06-27
NO20012995L (no) 2001-08-15
TR200101709T2 (tr) 2001-12-21
JP2002533326A (ja) 2002-10-08
HK1038744A1 (zh) 2002-03-28
AU760169B2 (en) 2003-05-08
CN1330637A (zh) 2002-01-09
ZA200103948B (en) 2002-11-15
NZ511478A (en) 2003-08-29
DE69919580T2 (de) 2005-09-01
DE69919580D1 (de) 2004-09-23
KR20010101258A (ko) 2001-11-14

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)