GB9821989D0 - Detection of nucleic acid polymorphism - Google Patents

Detection of nucleic acid polymorphism

Info

Publication number
GB9821989D0
GB9821989D0 GBGB9821989.2A GB9821989A GB9821989D0 GB 9821989 D0 GB9821989 D0 GB 9821989D0 GB 9821989 A GB9821989 A GB 9821989A GB 9821989 D0 GB9821989 D0 GB 9821989D0
Authority
GB
United Kingdom
Prior art keywords
duplex
complex
variation
single strand
probe
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB9821989.2A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hybaid Ltd
Original Assignee
Hybaid Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hybaid Ltd filed Critical Hybaid Ltd
Priority to GBGB9821989.2A priority Critical patent/GB9821989D0/en
Publication of GB9821989D0 publication Critical patent/GB9821989D0/en
Priority to DE69940698T priority patent/DE69940698D1/de
Priority to AU62160/99A priority patent/AU744929B2/en
Priority to PCT/GB1999/003329 priority patent/WO2000020633A1/en
Priority to AT99949176T priority patent/ATE427999T1/de
Priority to JP2000574725A priority patent/JP2002526123A/ja
Priority to EP99949176A priority patent/EP1117832B1/en
Priority to US09/755,747 priority patent/US7179589B2/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
GBGB9821989.2A 1998-10-08 1998-10-08 Detection of nucleic acid polymorphism Ceased GB9821989D0 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
GBGB9821989.2A GB9821989D0 (en) 1998-10-08 1998-10-08 Detection of nucleic acid polymorphism
DE69940698T DE69940698D1 (https=) 1998-10-08 1999-10-07
AU62160/99A AU744929B2 (en) 1998-10-08 1999-10-07 Detection of nucleic acid polymorphism
PCT/GB1999/003329 WO2000020633A1 (en) 1998-10-08 1999-10-07 Detection of nucleic acid polymorphism
AT99949176T ATE427999T1 (de) 1998-10-08 1999-10-07 Erkennung von nukleinsaurepolymorphismen
JP2000574725A JP2002526123A (ja) 1998-10-08 1999-10-07 核酸多形現象の検出
EP99949176A EP1117832B1 (en) 1998-10-08 1999-10-07 Detection of nucleic acid polymorphism
US09/755,747 US7179589B2 (en) 1998-10-08 2001-01-05 Detection of nucleic acid polymorphism

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9821989.2A GB9821989D0 (en) 1998-10-08 1998-10-08 Detection of nucleic acid polymorphism

Publications (1)

Publication Number Publication Date
GB9821989D0 true GB9821989D0 (en) 1998-12-02

Family

ID=10840243

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB9821989.2A Ceased GB9821989D0 (en) 1998-10-08 1998-10-08 Detection of nucleic acid polymorphism

Country Status (8)

Country Link
US (1) US7179589B2 (https=)
EP (1) EP1117832B1 (https=)
JP (1) JP2002526123A (https=)
AT (1) ATE427999T1 (https=)
AU (1) AU744929B2 (https=)
DE (1) DE69940698D1 (https=)
GB (1) GB9821989D0 (https=)
WO (1) WO2000020633A1 (https=)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6403313B1 (en) * 1999-12-21 2002-06-11 Ingeneus Corporation Fluorescent intensity assay for duplex and triplex nucleic acid hybridization solution utilizing fluorescent intercalators
US6900300B1 (en) 2000-09-19 2005-05-31 Ingeneus Corporation Quadruplex DNA and duplex probe systems
US6858390B2 (en) 1998-12-31 2005-02-22 Ingeneus Corporation Aptamers containing sequences of nucleic acid or nucleic acid analogues bound homologously, or in novel complexes
US6420115B1 (en) 1999-12-21 2002-07-16 Ingeneus Corporation Cation mediated triplex hybridization assay
US6656692B2 (en) 1999-12-21 2003-12-02 Ingeneus Corporation Parallel or antiparallel, homologous or complementary binding of nucleic acids or analogues thereof to form duplex, triplex or quadruplex complexes
US6911536B1 (en) 1999-12-21 2005-06-28 Ingeneus Corporation Triplex and quadruplex catalytic hybridization
US6927027B2 (en) 1999-12-21 2005-08-09 Ingeneus Corporation Nucleic acid multiplex formation
US7052844B2 (en) 1999-12-21 2006-05-30 Ingeneus, Inc. Purification of DS-DNA using heteropolymeric capture probes and a triplex, quadruplex or homologous duplex binding mechanism
US6924108B2 (en) 1999-12-21 2005-08-02 Ingeneus Corporation Nucleic acid binding enhancement by conjugation with nucleotides, nucleosides, bases and/or their analogues
US7309569B2 (en) 1999-12-21 2007-12-18 Ingeneus, Inc. Parallel or antiparallel, homologous or complementary binding of nucleic acids or analogues thereof to form duplex, triplex or quadruplex complexes
US6982147B2 (en) 2000-01-24 2006-01-03 Ingeneus Corporation Apparatus for assaying biopolymer binding by means of multiple measurements under varied conditions
US6613524B1 (en) 2000-01-24 2003-09-02 Ingeneus Corporation Amperometric affinity assay and electrically stimulated complexes of nucleic acids
US7220541B2 (en) 2000-01-24 2007-05-22 Ingeneus, Inc. Homogeneous assay of biopolymer binding by means of multiple measurements under varied conditions
US6506568B2 (en) 2000-02-10 2003-01-14 The Penn State Research Foundation Method of analyzing single nucleotide polymorphisms using melting curve and restriction endonuclease digestion
US20020182622A1 (en) * 2001-02-01 2002-12-05 Yusuke Nakamura Method for SNP (single nucleotide polymorphism) typing
CA2501144C (en) * 2002-10-23 2015-10-06 University Of Utah Research Foundation Amplicon melting analysis with saturation dyes
CA2429101A1 (en) * 2002-10-24 2004-04-24 Ben Gao Method and equipment to monitor nucleic acid hybridization on a dna chip using four-dimensional parameters
WO2004061130A1 (ja) * 2002-12-27 2004-07-22 Toyo Boseki Kabushiki Kaisha 塩基多型の同定方法
WO2004097371A2 (en) * 2003-04-25 2004-11-11 Board Of Regents, The University Of Texas System System and method for the detection of analytes
US9317922B2 (en) 2003-05-16 2016-04-19 Board Of Regents The University Of Texas System Image and part recognition technology
US8242254B2 (en) 2003-09-11 2012-08-14 Ibis Biosciences, Inc. Compositions for use in identification of bacteria
US9657347B2 (en) 2004-04-20 2017-05-23 University of Utah Research Foundation and BioFire Defense, LLC Nucleic acid melting analysis with saturation dyes
JP3916086B2 (ja) * 2004-06-29 2007-05-16 ソニー株式会社 ハイブリダイゼーションなどの相互作用を検出する方法及び検出部、該検出部を備えるバイオアッセイ用基板、ハイブリダイゼーションなどの相互作用を検出する装置、並びに試薬キット
US7745121B2 (en) 2005-05-23 2010-06-29 The Department Of Veterans Affairs Polymorphism in the macrophage migration inhibitory factor (MIF) gene as marker for prostate cancer
US20070072193A1 (en) * 2005-09-27 2007-03-29 Shah Manish M Ligand arrays having controlled feature size, and methods of making and using the same
US20070154892A1 (en) * 2005-12-30 2007-07-05 Simon Wain-Hobson Differential amplification of mutant nucleic acids by PCR in a mixure of nucleic acids
US8309304B2 (en) 2006-02-10 2012-11-13 The University Of Hong Kong Label-free optical sensing and characterization of biomolecules by d8 or d10 metal complexes
US8057989B2 (en) 2006-02-10 2011-11-15 The University Of Hong Kong Label-free optical sensing and characterization of biomolecules by d8 or d10 metal complexes
US7555933B2 (en) 2006-08-01 2009-07-07 Thermo Fisher Scientific Inc. Method and software for detecting vacuum concentrator ends-of-runs
WO2009130797A1 (ja) * 2008-04-22 2009-10-29 東洋鋼鈑株式会社 Abo式血液型を判定するためのプローブセット
US20110177515A1 (en) * 2008-05-30 2011-07-21 Ibis Biosciences, Inc. Compositions for use in identification of francisella
US8219324B2 (en) * 2008-09-12 2012-07-10 Roche Molecular Systems, Inc. Real-time PCR elbow calling by equation-less algorithm
US20100129796A1 (en) * 2008-11-24 2010-05-27 Micah Halpern Dye probe fluorescence resonance energy transfer genotyping
EP2436777B1 (en) 2009-05-26 2015-08-19 Xiamen University Method for detecting variations in nucleic acid sequences
US10176293B2 (en) 2012-10-02 2019-01-08 Roche Molecular Systems, Inc. Universal method to determine real-time PCR cycle threshold values
CN106908655B (zh) * 2017-03-06 2019-06-14 广东顺德工业设计研究院(广东顺德创新设计研究院) 光电信号峰值检测方法与系统

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4824776A (en) * 1985-07-25 1989-04-25 Molecular Biosystems, Inc. Method for increasing the sensitivity of nucleic acid hybridization assays
EP0478319B1 (en) * 1990-09-28 1997-04-02 Kabushiki Kaisha Toshiba Gene detection method
US6048690A (en) * 1991-11-07 2000-04-11 Nanogen, Inc. Methods for electronic fluorescent perturbation for analysis and electronic perturbation catalysis for synthesis
AU3140293A (en) * 1991-11-22 1993-06-15 United States of America, as represented by the Secretary, U.S. Department of Commerce, The Device and method for detection of compounds which intercalate with nucleic acids
CA2170264A1 (en) * 1993-09-10 1995-03-16 Michael W. Konrad Optical detection of position of oligonucleotides on large dna molecules
JPH09503660A (ja) * 1993-09-23 1997-04-15 ゼネカ・リミテッド エネルギー移動による核酸検出
JP4540754B2 (ja) * 1996-06-04 2010-09-08 ユニバーシティ オブ ユタ リサーチ ファウンデーション Ｐｃｒ中のハイブリダイゼーションのモニタリング
AU6534898A (en) * 1997-02-14 1998-09-08 E.I. Du Pont De Nemours And Company Detection of double-stranded dna in a homogeneous solution
US6406845B1 (en) * 1997-05-05 2002-06-18 Trustees Of Tuft College Fiber optic biosensor for selectively detecting oligonucleotide species in a mixed fluid sample
GB9725197D0 (en) * 1997-11-29 1998-01-28 Secr Defence Detection system
WO2002059584A2 (en) * 2000-12-29 2002-08-01 Chromagen, Inc. Scanning spectrophotometer for high throughput fluorescence detection

Also Published As

Publication number Publication date
AU744929B2 (en) 2002-03-07
ATE427999T1 (de) 2009-04-15
JP2002526123A (ja) 2002-08-20
DE69940698D1 (https=) 2009-05-20
EP1117832A1 (en) 2001-07-25
US20010046670A1 (en) 2001-11-29
AU6216099A (en) 2000-04-26
EP1117832B1 (en) 2009-04-08
WO2000020633A1 (en) 2000-04-13
US7179589B2 (en) 2007-02-20

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)