GB920639A - New halogeno-androstenes - Google Patents

New halogeno-androstenes

Info

Publication number
GB920639A
GB920639A GB2156359A GB2156359A GB920639A GB 920639 A GB920639 A GB 920639A GB 2156359 A GB2156359 A GB 2156359A GB 2156359 A GB2156359 A GB 2156359A GB 920639 A GB920639 A GB 920639A
Authority
GB
United Kingdom
Prior art keywords
acids
esters
androstenes
halogeno
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2156359A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF Schweiz AG
Original Assignee
Ciba AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba AG filed Critical Ciba AG
Publication of GB920639A publication Critical patent/GB920639A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Abstract

The invention comprises D 4-9a -chloro- and -fluoro - 17a - methyl-3b :11b :17b -trihydroxyandrostenes and 3-esters thereof. They are prepared by reduction with a complex lightmetal hydride of the corresponding 3-ones with subsequent esterification if desired. Esters of saturated and unsaturated aliphatic, cycloaliphatic, aromatic and heterocyclic carboxylic acids, including amino-acids and halogencontaining acids, of sulphonic, phosphoric and sulphuric acids, and semi-esters of dicarboxylic acids in which the free carboxyl group may also be esterified, or salified with alkali metals or organic bases, are described. The androstenes of the invention, which are stated to be highly androgenic, may be made up with suitable carriers into pharmaceutical preparations. These may take the form of oily or aqueous solutions, ampoules, suspensions, emulsions, implants, tablets, dragees, ointments or creams, and may contain preservatives, stabilizers, wetting agents, salts for varying the osmotic pressure or buffers.
GB2156359A 1958-06-25 1959-06-23 New halogeno-androstenes Expired GB920639A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH6100558A CH367824A (en) 1958-06-25 1958-06-25 Process for the production of new haloandrostenes

Publications (1)

Publication Number Publication Date
GB920639A true GB920639A (en) 1963-03-13

Family

ID=4523337

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2156359A Expired GB920639A (en) 1958-06-25 1959-06-23 New halogeno-androstenes

Country Status (3)

Country Link
CH (1) CH367824A (en)
ES (1) ES250199A1 (en)
GB (1) GB920639A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4354977A (en) * 1979-03-15 1982-10-19 Commonwealth Scientific And Industrial Research Organization Phosphonothioate immunogens

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4354977A (en) * 1979-03-15 1982-10-19 Commonwealth Scientific And Industrial Research Organization Phosphonothioate immunogens

Also Published As

Publication number Publication date
CH367824A (en) 1963-03-15
ES250199A1 (en) 1959-10-16

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