GB896787A - New theophyllin compounds and their production - Google Patents

New theophyllin compounds and their production

Info

Publication number
GB896787A
GB896787A GB34353/58A GB3435358A GB896787A GB 896787 A GB896787 A GB 896787A GB 34353/58 A GB34353/58 A GB 34353/58A GB 3435358 A GB3435358 A GB 3435358A GB 896787 A GB896787 A GB 896787A
Authority
GB
United Kingdom
Prior art keywords
general formula
theophyllin
compounds
new
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB34353/58A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
INGEBORG VON WUELFING
TILLYTA IGLER VON WUELFING
Wuelfing & Co A GmbH
Original Assignee
INGEBORG VON WUELFING
TILLYTA IGLER VON WUELFING
Wuelfing & Co A GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by INGEBORG VON WUELFING, TILLYTA IGLER VON WUELFING, Wuelfing & Co A GmbH filed Critical INGEBORG VON WUELFING
Publication of GB896787A publication Critical patent/GB896787A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention comprises theophyllin bases of the general formula <FORM:0896787/IV (b)/1> (wherein R1 and R2 represent alkyl or hydroxyalkyl groups) and their acid addition salts (e.g. nicotinates), and the preparation thereof by heating a 7-(g -halo-b -hydroxypropyl)-xanthine of the general formula <FORM:0896787/IV (b)/2> (wherein X represents a halogen) with a secondary amine or by reacting theophyllin with a haloalkanolamine of the general formula X-CH2-CH(OH)-CH2-NR1R2 in the presence of an alkali metal hydroxide or carbonate. The products are useful for treating diseases of the peripheral blood vessels. Haloalkanolamines of the last general formula above are prepared by reacting epihalohydrins with secondary amines in a hydroxylic solvent.
GB34353/58A 1957-10-26 1958-10-27 New theophyllin compounds and their production Expired GB896787A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE896787X 1957-10-26

Publications (1)

Publication Number Publication Date
GB896787A true GB896787A (en) 1962-05-16

Family

ID=6848363

Family Applications (1)

Application Number Title Priority Date Filing Date
GB34353/58A Expired GB896787A (en) 1957-10-26 1958-10-27 New theophyllin compounds and their production

Country Status (1)

Country Link
GB (1) GB896787A (en)

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