GB891004A - Improvements in or relating to tetrocycline derivatives - Google Patents

Improvements in or relating to tetrocycline derivatives

Info

Publication number
GB891004A
GB891004A GB10887/59A GB1088759A GB891004A GB 891004 A GB891004 A GB 891004A GB 10887/59 A GB10887/59 A GB 10887/59A GB 1088759 A GB1088759 A GB 1088759A GB 891004 A GB891004 A GB 891004A
Authority
GB
United Kingdom
Prior art keywords
salt
tetracycline
water
diethylenediamino
specifications
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB10887/59A
Inventor
Boris Gradnik
Andrea Pedrazzoli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RECH S ET D APPLIC SCIENT ET M
Original Assignee
RECH S ET D APPLIC SCIENT ET M
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to GB2984957A priority Critical patent/GB897286A/en
Application filed by RECH S ET D APPLIC SCIENT ET M filed Critical RECH S ET D APPLIC SCIENT ET M
Priority to GB10887/59A priority patent/GB891004A/en
Priority to FR1586601D priority patent/FR1586601A/fr
Priority to BE588706A priority patent/BE588706A/en
Priority to CH301360A priority patent/CH394492A/en
Priority to DES67727A priority patent/DE1142170B/en
Priority to SE3107/60A priority patent/SE303278B/xx
Priority to BR118213/60A priority patent/BR6018213D0/en
Priority to ES0256969A priority patent/ES256969A1/en
Priority to FR835979A priority patent/FR521M/fr
Publication of GB891004A publication Critical patent/GB891004A/en
Expired legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B9/00—Spraying apparatus for discharge of liquids or other fluent material, without essentially mixing with gas or vapour
    • B05B9/03—Spraying apparatus for discharge of liquids or other fluent material, without essentially mixing with gas or vapour characterised by means for supplying liquid or other fluent material
    • B05B9/04—Spraying apparatus for discharge of liquids or other fluent material, without essentially mixing with gas or vapour characterised by means for supplying liquid or other fluent material with pressurised or compressible container; with pump
    • B05B9/08—Apparatus to be carried on or by a person, e.g. of knapsack type
    • B05B9/085—Apparatus to be carried on or by a person, e.g. of knapsack type with a liquid pump
    • B05B9/0877—Apparatus to be carried on or by a person, e.g. of knapsack type with a liquid pump the pump being of pressure-accumulation type or being connected to a pressure accumulation chamber
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention relates to a salt of phenoxy-methylpenicillin wit N-[41-(betahydroxy ethyl)-diethylenediamino - 11 - methyl] tetracycline of formula <FORM:0891004/IV (b)/1> The salt is produced by reacting equimolar amounts of the penicillin and tetracycline in an inert solvent such as water or methanol and lyophilizing (water) or precipitating by the addition of ether (methanol). The salt is soluble in water and may be injected (see Group VI). Specifications 774,753 and 888,968 are referred to.ALSO:An injectable composition comprises an aqueous solution of a salt of phenoxymethyl penicillin with N - [41 -(betahydroxyethyl)-diethylenediamino - 11 - methyl] tetracycline which salt has the formula <FORM:0891004/VI/1> <FORM:0891004/VI/2> Specifications 774,753 and 888,968 are referred to.
GB10887/59A 1957-09-23 1959-03-31 Improvements in or relating to tetrocycline derivatives Expired GB891004A (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
GB2984957A GB897286A (en) 1957-09-23 1957-09-23 Improvements in or relating to portable spraying apparatus
GB10887/59A GB891004A (en) 1959-03-31 1959-03-31 Improvements in or relating to tetrocycline derivatives
FR1586601D FR1586601A (en) 1959-03-31 1960-03-15
BE588706A BE588706A (en) 1959-03-31 1960-03-16 New chemical compound with antibiotic action
CH301360A CH394492A (en) 1959-03-31 1960-03-17 Process for preparing a new antibiotic
DES67727A DE1142170B (en) 1959-03-31 1960-03-24 Process for the preparation of a new compound of phenoxymethylpenicillin
SE3107/60A SE303278B (en) 1959-03-31 1960-03-29
BR118213/60A BR6018213D0 (en) 1959-03-31 1960-03-29 PROCESS FOR PREPARING N2 (OR 9 OR 7) PHENOXY-METHYL-PENICILLATE -4 (BETA-HYDROXY-ETHYL) DI-ETHYLENE-DIAMINE-METHYL-TETRA-CYCLINE
ES0256969A ES256969A1 (en) 1959-03-31 1960-03-30 Improvements in or relating to tetrocycline derivatives
FR835979A FR521M (en) 1959-03-31 1960-08-17

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB10887/59A GB891004A (en) 1959-03-31 1959-03-31 Improvements in or relating to tetrocycline derivatives

Publications (1)

Publication Number Publication Date
GB891004A true GB891004A (en) 1962-03-07

Family

ID=9976135

Family Applications (1)

Application Number Title Priority Date Filing Date
GB10887/59A Expired GB891004A (en) 1957-09-23 1959-03-31 Improvements in or relating to tetrocycline derivatives

Country Status (8)

Country Link
BE (1) BE588706A (en)
BR (1) BR6018213D0 (en)
CH (1) CH394492A (en)
DE (1) DE1142170B (en)
ES (1) ES256969A1 (en)
FR (2) FR1586601A (en)
GB (1) GB891004A (en)
SE (1) SE303278B (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE569728A (en) *
DE1044806B (en) * 1956-10-03 1958-11-27 Hoechst Ag Process for the preparation of water-soluble derivatives of the tetracyclines

Also Published As

Publication number Publication date
FR521M (en) 1961-05-23
BR6018213D0 (en) 1973-05-24
ES256969A1 (en) 1960-10-16
BE588706A (en) 1960-07-18
DE1142170B (en) 1963-01-10
SE303278B (en) 1968-08-26
FR1586601A (en) 1970-02-27
CH394492A (en) 1965-06-30

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