GB831256A - Process for the preparation of steroid compounds - Google Patents

Process for the preparation of steroid compounds

Info

Publication number
GB831256A
GB831256A GB33367/57A GB3336757A GB831256A GB 831256 A GB831256 A GB 831256A GB 33367/57 A GB33367/57 A GB 33367/57A GB 3336757 A GB3336757 A GB 3336757A GB 831256 A GB831256 A GB 831256A
Authority
GB
United Kingdom
Prior art keywords
pregnadiene
dione
keto
steroids
diol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB33367/57A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Charles Pfizer and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc, Charles Pfizer and Co Inc filed Critical Pfizer Inc
Publication of GB831256A publication Critical patent/GB831256A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

3-Keto- D 1,4-steroids, 3-keto- D 4-steroids or a mixture thereof are obtained in a process which comprises contacting a 3-keto-nuclear saturated steroid with the oxidizing enzymes produced by growing an organism of the species Micromonospora chalcea. The fermentation may be effected under submerged aerated conditions, by means of a growing culture. Altvernatively there may be employed cells removed from the growing culture, or enzymes obtained by rupture of the cells. Specified products are D 1,4 - pregnadiene - 11b ,17a ,21-triol - 3,20 - dione, D 1,4 - pregnadiene - 17a ,21-diol - 3,11,20 - trione, D 1,4 - pregnadiene - 11b ,21 - diol - 3,20 - dione, D 1,4 - pregnadiene-11b ,14a ,17a ,21 - tetrol - 3,20 - dione and D 1,4-pregnadiene-21-ol-3,20-dione.
GB33367/57A 1957-02-12 1957-10-25 Process for the preparation of steroid compounds Expired GB831256A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US831256XA 1957-02-12 1957-02-12

Publications (1)

Publication Number Publication Date
GB831256A true GB831256A (en) 1960-03-23

Family

ID=22176343

Family Applications (1)

Application Number Title Priority Date Filing Date
GB33367/57A Expired GB831256A (en) 1957-02-12 1957-10-25 Process for the preparation of steroid compounds

Country Status (1)

Country Link
GB (1) GB831256A (en)

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