GB786917A - Para-aminosalicylic acids - Google Patents

Para-aminosalicylic acids

Info

Publication number
GB786917A
GB786917A GB23488/55A GB2348855A GB786917A GB 786917 A GB786917 A GB 786917A GB 23488/55 A GB23488/55 A GB 23488/55A GB 2348855 A GB2348855 A GB 2348855A GB 786917 A GB786917 A GB 786917A
Authority
GB
United Kingdom
Prior art keywords
solution
isopropanol
water
acid
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB23488/55A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Miles Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miles Laboratories Inc filed Critical Miles Laboratories Inc
Publication of GB786917A publication Critical patent/GB786917A/en
Expired legal-status Critical Current

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Abstract

A pure, dense form of p-aminosalicylic acid is prepared by forming a solution of an alkali metal salt of the acid in a water-isopropanol medium and acidifying the solution to precipitate p-aminosalicylic acid. The salt can be dissolved in aqueous isopropanol, or, alternatively, can be dissolved in water and isopropanol added to the solution so formed, either before or as the solution is acidified. A surface-active agent may be added to the water-isopropanol medium. Any acid capable of precipitating p-aminosalicylic acid from a solution of an alkali metal salt thereof may be used, hydrochloric, sulphuric and formic acids being specified. The process of the invention is illustrated in examples, the following additional features being described (a) sodium bisulphite or hydrosulphite present in the water-isopropanol medium and (b) preliminary treatment of the aqueous salt solution with activated carbon.
GB23488/55A 1954-09-13 1955-08-15 Para-aminosalicylic acids Expired GB786917A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US786917XA 1954-09-13 1954-09-13

Publications (1)

Publication Number Publication Date
GB786917A true GB786917A (en) 1957-11-27

Family

ID=22145637

Family Applications (1)

Application Number Title Priority Date Filing Date
GB23488/55A Expired GB786917A (en) 1954-09-13 1955-08-15 Para-aminosalicylic acids

Country Status (1)

Country Link
GB (1) GB786917A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111848432A (en) * 2020-07-15 2020-10-30 广药白云山化学制药(珠海)有限公司 Preparation method of p-aminosalicylic acid

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111848432A (en) * 2020-07-15 2020-10-30 广药白云山化学制药(珠海)有限公司 Preparation method of p-aminosalicylic acid

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