GB749200A - Pregnadienes - Google Patents
PregnadienesInfo
- Publication number
- GB749200A GB749200A GB23628/53A GB2362853A GB749200A GB 749200 A GB749200 A GB 749200A GB 23628/53 A GB23628/53 A GB 23628/53A GB 2362853 A GB2362853 A GB 2362853A GB 749200 A GB749200 A GB 749200A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hydroxy
- pregnadiene
- compound
- acyloxy
- dione
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The invention comprises a compound having the formula: <FORM:0749200/IV(a)/1> wherein R is a hydrogen atom or an acyl radical of a hydrocarbon carboxylic acid containing from one to eight carbon atoms, inclusive, and the preparation of the 21-acyloxy compound by oxidation of an 11-hydroxy-21-lower acyloxy-4,17(20)-pregnadiene-3-one by means of an oxidizing agent capable of converting an 11b -hydroxy group to an 11-keto group, e.g. N-bromoacetamide, N-bromosuccinimide or N-chlorosuccinimide in pyridine or chromic acid in acetic acid, and of the corresponding 21-hydroxy compound by hydrolysis or saponification of a 21-acyloxy-4,17(20)-pregnadiene-3,11-dione. Examples describe the production of 21-acetoxy and 21-hydroxy-4,17(20)-pregnadiene-3,11-dione. Specifications 733,448, 749,195, 749,198, 749,199 and 749,201 are referred to.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US749200XA | 1952-08-30 | 1952-08-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB749200A true GB749200A (en) | 1956-05-23 |
Family
ID=22122444
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB23628/53A Expired GB749200A (en) | 1952-08-30 | 1953-08-26 | Pregnadienes |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB749200A (en) |
-
1953
- 1953-08-26 GB GB23628/53A patent/GB749200A/en not_active Expired
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