GB738631A - Compounds of the cyclopentanopolyhydrophenanthrene series and a method of making same - Google Patents

Compounds of the cyclopentanopolyhydrophenanthrene series and a method of making same

Info

Publication number
GB738631A
GB738631A GB3955/54A GB395554A GB738631A GB 738631 A GB738631 A GB 738631A GB 3955/54 A GB3955/54 A GB 3955/54A GB 395554 A GB395554 A GB 395554A GB 738631 A GB738631 A GB 738631A
Authority
GB
United Kingdom
Prior art keywords
compounds
androstan
methyl
making same
diol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3955/54A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of GB738631A publication Critical patent/GB738631A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention comprises compounds of the general formula <FORM:0738631/IV (b)/1> which represents a cyclopentanopolyhydrophenanthrene ring system having the <FORM:0738631/IV (b)/2> grouping in the 3-position and a keto group in the 17-position, and wherein R is a saturated or unsaturated aliphatic hydrocarbon residue. The compounds are prepared by oxidation of the corresponding 17-hydroxy derivatives. In examples: (1) 3a-methyl-androstan-3b : 17b -diol is oxidized with chromic acid in glacial acetic to yield 3a - methyl - androstan - 3b - ol - 17 - one; (2) 3b-methyl-androstan-3a : 17a -diol is oxidized as in (1) to produce 3b-methyl-androstan-3a-ol-17-one. The compounds obtained exhibit anti-hormonal activity. Specification 738,576 is referred to.
GB3955/54A 1951-04-06 1952-04-04 Compounds of the cyclopentanopolyhydrophenanthrene series and a method of making same Expired GB738631A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE738631X 1951-04-06

Publications (1)

Publication Number Publication Date
GB738631A true GB738631A (en) 1955-10-19

Family

ID=6642838

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3955/54A Expired GB738631A (en) 1951-04-06 1952-04-04 Compounds of the cyclopentanopolyhydrophenanthrene series and a method of making same

Country Status (1)

Country Link
GB (1) GB738631A (en)

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