ES282759A1 - Procedure for the preparation of 6,16-dimethyl-15-dehydro-steroids (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the preparation of 6,16-dimethyl-15-dehydro-steroids (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES282759A1 ES282759A1 ES0282759A ES282759A ES282759A1 ES 282759 A1 ES282759 A1 ES 282759A1 ES 0282759 A ES0282759 A ES 0282759A ES 282759 A ES282759 A ES 282759A ES 282759 A1 ES282759 A1 ES 282759A1
- Authority
- ES
- Spain
- Prior art keywords
- dimethyl
- dehydro
- treatment
- translation
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Abstract
Process for the preparation of 6,16-dimethyl-15-dehydro steroids of the formula I ** (See formula) ** in which R = alpha-H, beta-OH or = 0 X = H o F Y = free or esterified hydroxy group as well as its derivatives Δ1, Δ6 and Δ1,6, characterized in that in a 6,16-dimethyl-15-dehydro-steroid of the formula ** (See formula) ** in which X = H o F Y 1 = H or free or esterified hydroxy group R1 = H,H; H,OH o = 0 one or two double bonds are introduced in position 1 and/or 6 by treatment with a dehydrogenating agent, and if it means hydrogen, an 11-hydroxyl group is introduced by treatment with 11-hydroxylating microorganisms and, if Y1, hydrogen is introduced a 21-ester group by consecutive treatment with alkaline solution of iodine and alkali acylate, as well as, optionally, if X means hydrogen, a 9-alpha-fluorine atom is introduced by cleavage of the 9beta, corresponding 11beta-epoxide with hydrofluoric acid and an 11-hydroxy steroid thus obtained is optionally converted by treatment with a mild oxidizing agent into the corresponding keto steroid and optionally a 21-hydroxy group is esterified or a 21-ester group is saponified. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE282759X | 1961-11-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES282759A1 true ES282759A1 (en) | 1963-07-01 |
Family
ID=38569796
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0282759A Expired ES282759A1 (en) | 1961-11-24 | 1962-11-23 | Procedure for the preparation of 6,16-dimethyl-15-dehydro-steroids (Machine-translation by Google Translate, not legally binding) |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES282759A1 (en) |
-
1962
- 1962-11-23 ES ES0282759A patent/ES282759A1/en not_active Expired
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