ES280807A1 - Procedure for preparing 6-alpha-methyl-16-methylene-steroids (Machine-translation by Google Translate, not legally binding)
- Google Patents
Procedure for preparing 6-alpha-methyl-16-methylene-steroids (Machine-translation by Google Translate, not legally binding)
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Merck KGaA
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E Merck AG
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Publication of ES280807A1publicationCriticalpatent/ES280807A1/en
Process for preparing 6alpha-methyl-16-methylene-steroids of the formula I ** (See formula) ** in which R1 = free or esterified hydroxyl group Hg = alphaH, betaOH or well = 0 and Y = H o F, characterized in that the fundamental steroid, saturated in position 1,2, is dehydrogenated in the 1,2-position by microbiological route, or an O-acyl group in the 21-position is introduced into the corresponding 21-deoxy compound, or optionally a hydroxyl group located at position 21 is esterified, or a 21-ester group is saponified, either an 11-hydroxyl group is oxidized, by treatment with a mild oxidant, to convert it to 11-keto group, or , for the preparation of compounds in which Y = F, the 9beta, 11beta-oxido-steroid, is treated with hydrofluoric acid. (Machine-translation by Google Translate, not legally binding)
ES0280807A1961-09-151962-09-14Procedure for preparing 6-alpha-methyl-16-methylene-steroids (Machine-translation by Google Translate, not legally binding)
ExpiredES280807A1
(en)
Novel processes for preparing steroid compounds, the comopounds when thus prepared, novel steroid compounds thereby prepared, and pharmaceutical compositions containing the novel compounds
Procedure for the preparation of 9-alpha-16 - fluor-16 - metilenprednisolona or prednisona and its 21-esteres. (Machine-translation by Google Translate, not legally binding)
A procedure for preparing the 21-hydroxy steroids of the pregnan series esterified in the position 21. (Machine-translation by Google Translate, not legally binding)