ES319114A1 - A procedure for preparing the 21-hydroxy steroids of the pregnan series esterified in the position 21. (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for preparing the 21-hydroxy steroids of the pregnan series esterified in the position 21. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES319114A1
ES319114A1 ES0319114A ES319114A ES319114A1 ES 319114 A1 ES319114 A1 ES 319114A1 ES 0319114 A ES0319114 A ES 0319114A ES 319114 A ES319114 A ES 319114A ES 319114 A1 ES319114 A1 ES 319114A1
Authority
ES
Spain
Prior art keywords
esterified
translation
procedure
machine
legally binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0319114A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of ES319114A1 publication Critical patent/ES319114A1/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J75/00Processes for the preparation of steroids in general

Abstract

A procedure for the preparation of the 21-hydroxy steroids of the pregnane series esterified in position 21 which correspond to the general formula: ** (See formula) ** wherein St represents a steroid radical, where R: H, OH or OR 'is represented by R', a lower acyl radical, where n and hereinafter an integer less than 3, characterized in that it is esterified in position 21 , a 20-oxo 21-hydroxy steroid of the pregnane series with an organic acid of formula ** (See formula) ** or a functional derivative of this. (Machine-translation by Google Translate, not legally binding)
ES0319114A 1964-11-04 1965-10-30 A procedure for preparing the 21-hydroxy steroids of the pregnan series esterified in the position 21. (Machine-translation by Google Translate, not legally binding) Expired ES319114A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR993810A FR1514082A (en) 1964-11-04 1964-11-04 New steroid esters at position 21 and method of preparation

Publications (1)

Publication Number Publication Date
ES319114A1 true ES319114A1 (en) 1965-12-16

Family

ID=8841771

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0319114A Expired ES319114A1 (en) 1964-11-04 1965-10-30 A procedure for preparing the 21-hydroxy steroids of the pregnan series esterified in the position 21. (Machine-translation by Google Translate, not legally binding)

Country Status (12)

Country Link
AT (1) AT257853B (en)
BE (1) BE671392A (en)
BR (1) BR6574584D0 (en)
CH (1) CH445484A (en)
DE (1) DE1468945A1 (en)
DK (1) DK113920B (en)
ES (1) ES319114A1 (en)
FR (1) FR1514082A (en)
GB (1) GB1087730A (en)
IL (1) IL24502A (en)
NL (2) NL6514035A (en)
SE (1) SE309776B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2183555B1 (en) * 1972-05-10 1975-06-20 Roussel Uclaf
US4472392A (en) * 1983-01-21 1984-09-18 The Upjohn Company Sulfonate containing ester prodrugs of corticosteroids

Also Published As

Publication number Publication date
NL124139C (en)
GB1087730A (en) 1967-10-18
FR1514082A (en) 1968-02-23
BE671392A (en) 1966-04-25
BR6574584D0 (en) 1973-09-18
AT257853B (en) 1967-10-25
SE309776B (en) 1969-04-08
CH445484A (en) 1967-10-31
IL24502A (en) 1969-12-31
NL6514035A (en) 1966-05-05
DE1468945A1 (en) 1969-02-06
DK113920B (en) 1969-05-12

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