GB631502A - Process of preparing hemostatic compositions - Google Patents
Process of preparing hemostatic compositionsInfo
- Publication number
- GB631502A GB631502A GB20334/47A GB2033447A GB631502A GB 631502 A GB631502 A GB 631502A GB 20334/47 A GB20334/47 A GB 20334/47A GB 2033447 A GB2033447 A GB 2033447A GB 631502 A GB631502 A GB 631502A
- Authority
- GB
- United Kingdom
- Prior art keywords
- thrombin
- precipitate
- amino acid
- salt water
- solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4833—Thrombin (3.4.21.5)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
A haemostatic composition is prepared by recovering thrombin from blood plasma, dissolving the thrombin in salt water, adding to the solution a support for thrombin consisting of an amino acid which is soluble in salt water and insoluble in the organic liquids which precipitate thrombin, which absorbs thrombin in a labile manner and which has no detrimental action on parenteral injection, cooling the solution, precipitating both thrombin and the support with an organic liquid, allowing the precipitate to settle in the cold, draining and drying it in vacuo. Glycocoll is the preferred amino acid, and alcohol or acetone are the preferred precipitating liquids. The product is used as a haemostatic in general, or particularly for parental intramuscular or oral administration. The Specification as open to inspection under Sect. 91 also refers to holosides and sugars as suitable supports. This subject-matter does not appear in the Specification as accepted.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR631502X | 1946-02-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB631502A true GB631502A (en) | 1949-11-03 |
Family
ID=8991802
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB20334/47A Expired GB631502A (en) | 1946-02-04 | 1947-07-28 | Process of preparing hemostatic compositions |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB631502A (en) |
-
1947
- 1947-07-28 GB GB20334/47A patent/GB631502A/en not_active Expired
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB631502A (en) | Process of preparing hemostatic compositions | |
| GB779493A (en) | Process for the isolation of stable, highly purified gamma globulin preparations | |
| GB855153A (en) | Spin-dyeing of acrylonitrile polymers | |
| GB655349A (en) | Improvements in or relating to the preparation of cyclic 1,2-ketols having from 10 to 18 carbon atoms in the ring | |
| Quick | The components of prothrombin | |
| GB604947A (en) | Method of improving the adsorbent properties of alumina | |
| Carson et al. | Esterification of Subtilin and its Effect on Solubility and in vitro Bacteriostatic Activity | |
| GB1443053A (en) | Cancer associated polypeptide antigen process for its pre paration and composition useful as an immunizing agent | |
| GB240174A (en) | An improved process for the manufacture of artificial horn from proteins or albuminous substances | |
| GB573721A (en) | Improvements in or relating to the production of food | |
| US2288965A (en) | Pbocess fob the manufacture of | |
| GB621820A (en) | Process for the production of a derivative of benzotetronic acid | |
| GB165779A (en) | Process for the manufacture of easily and neutrally soluble double compounds of 1-allyl-3.7-dimethylxanthine | |
| GB123971A (en) | Improved Manufacture of Decolorised, Odourless and Tasteless Albumins from Blood. | |
| GB669460A (en) | Improvements in or relating to plastic product and process of manufacturing same | |
| GB482826A (en) | Manufacture of extracts of spleen or liver | |
| GB606559A (en) | Improvements in or relating to the production of blood-coagulating agents | |
| ES379037A1 (en) | Improvements in the procedures for the preparation of olives. (Machine-translation by Google Translate, not legally binding) | |
| GB161294A (en) | Improvements in the fermentation of cellulose | |
| GB214628A (en) | ||
| GB460193A (en) | Process for the manufacture of a stable product therapeutically useful in relation to bleeding | |
| GB712515A (en) | Process of fractionating purified tuberculins | |
| GB665127A (en) | An improved process for the manufacture of guanidine and salts thereof | |
| GB607490A (en) | Improvements in the process for obtaining 4-4'-dioxi-3-3'-diamino-arseno-benzene-sodium-methane-sulphoxylate | |
| GB1058917A (en) | Monohydrate of the equimolecular complex of ascorbic acid and pyridoxine base, and process for its preparation |