GB577122A - Mydriatic compounds - Google Patents
Mydriatic compoundsInfo
- Publication number
- GB577122A GB577122A GB802944A GB802944A GB577122A GB 577122 A GB577122 A GB 577122A GB 802944 A GB802944 A GB 802944A GB 802944 A GB802944 A GB 802944A GB 577122 A GB577122 A GB 577122A
- Authority
- GB
- United Kingdom
- Prior art keywords
- mandelic acid
- methylpiperidinol
- hydrochloride
- ether
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
N-Methylpiperidinol-4 or its salts, e.g. the hydrochloride, phosphate, sulphate, tartrate, oxalate, malate or succinate are treated with mandelic acid in dilute acid solution to yield either the mandelate or the corresponding salt of this ester. In an example: N-methylpiperidinol hydrochloride and mandelic acid are heated at 95 DEG C. with 10 per cent hydrochloric acid for 40 hours, prior to diluting with water, extracting unreacted mandelic acid with ether, and making the aqueous layer alkaline with sodium carbonate, followed by re-extraction with ether and treatment of the ethereal solution with gaseous hydrogen chloride to isolate the product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB802944A GB577122A (en) | 1944-04-28 | 1944-04-28 | Mydriatic compounds |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB802944A GB577122A (en) | 1944-04-28 | 1944-04-28 | Mydriatic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB577122A true GB577122A (en) | 1946-05-06 |
Family
ID=9844404
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB802944A Expired GB577122A (en) | 1944-04-28 | 1944-04-28 | Mydriatic compounds |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB577122A (en) |
-
1944
- 1944-04-28 GB GB802944A patent/GB577122A/en not_active Expired
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB662800A (en) | Improvements in or relating to the preparation of salts of cyclohexylsulphamic acid | |
| GB577122A (en) | Mydriatic compounds | |
| GB497093A (en) | A process for the production of mono-alkylolamines or mixtures containing such amines | |
| GB553317A (en) | Improvements in the production of alkaline earth metal pantothenates | |
| GB734934A (en) | Improvements in and relating to phenanthridine compounds and the manufacture thereof | |
| GB815377A (en) | Improvements in or relating to the production of beer malt | |
| GB706409A (en) | Process for the preparation of diethylaminoaceto-2m-xylidide | |
| GB680485A (en) | Cleansing and sterilising beer handling equipment | |
| GB624568A (en) | Process for the manufacture of thioglycollic acid or its salts | |
| GB383112A (en) | Process for the production of aluminium derivatives of acetyl-salicy lic acid | |
| GB672164A (en) | A process for the manufacture of pentaenes | |
| GB772966A (en) | Preparation of 2,4,5-trichlorophenoxyacetic acid | |
| GB635568A (en) | Process for the manufacture of antiseptic eye lotions | |
| GB1001704A (en) | Process for the production of water soluble derivatives of ªÐ-amino-salicylic acid | |
| GB379677A (en) | Improvements in and relating to therapeutic compounds containing silver | |
| GB473078A (en) | Process for the manufacture of urea and formaldehyde varnishes and product obtained | |
| GB633459A (en) | A process for the manufacture of n-(p-arsenosobenzyl)-glycine-amide and salts thereof | |
| GB565982A (en) | Manufacture of tetrahydro-p-oxazinylmethyl-benzo-dioxane | |
| GB583221A (en) | Improvements in the manufacture of mepacrine hydrochloride | |
| GB617190A (en) | Esters of salicyclic acid | |
| GB483945A (en) | Process for the preparation of new compounds of therapeutic value | |
| GB510138A (en) | Process for the manufacture of ª‡-naphthacetyl-amino acids | |
| GB360299A (en) | Improvements in the production of formic acid | |
| GB414941A (en) | Process for the production of a new water-soluble derivative of 8-hydroxyquinoline | |
| GB676153A (en) | N-isopropylaminopropiophenones |