GB573719A - Process for the enrichment of vitamin e active compounds - Google Patents

Process for the enrichment of vitamin e active compounds

Info

Publication number
GB573719A
GB573719A GB29804/39A GB2980439A GB573719A GB 573719 A GB573719 A GB 573719A GB 29804/39 A GB29804/39 A GB 29804/39A GB 2980439 A GB2980439 A GB 2980439A GB 573719 A GB573719 A GB 573719A
Authority
GB
United Kingdom
Prior art keywords
vitamin
esterified
high vacuum
wheat germ
germ oil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB29804/39A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of GB573719A publication Critical patent/GB573719A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355Tocopherols, e.g. vitamin E

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Natural substances having vitamin E activity such as wheat germ oil concentrates are esterified with lower fatty acids, the product being then fractionated by high vacuum distillation to concentrate the esterified vitamin E. In examples: (1) the unsaponifiable portion of wheat germ oil is esterified with acetic anhydride and sodium acetate and after removal of the excess acetylating agent the sterol esters are precipitated by adding solvents such as methyl alcohol, acetone or petroleum ether, and the remaining solution is distilled under high vacuum; (2) the unsaponifiable portion of cotton seed oil is dissolved in pyridine and heated with butyric anhydride, the reaction product being treated as above.
GB29804/39A 1938-11-30 1939-11-10 Process for the enrichment of vitamin e active compounds Expired GB573719A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH573719X 1938-11-30

Publications (1)

Publication Number Publication Date
GB573719A true GB573719A (en) 1945-12-04

Family

ID=4521070

Family Applications (1)

Application Number Title Priority Date Filing Date
GB29804/39A Expired GB573719A (en) 1938-11-30 1939-11-10 Process for the enrichment of vitamin e active compounds

Country Status (1)

Country Link
GB (1) GB573719A (en)

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