GB396135A - Manufacture of an adenosine phosphoric acid - Google Patents
Manufacture of an adenosine phosphoric acidInfo
- Publication number
- GB396135A GB396135A GB5263/32A GB526332A GB396135A GB 396135 A GB396135 A GB 396135A GB 5263/32 A GB5263/32 A GB 5263/32A GB 526332 A GB526332 A GB 526332A GB 396135 A GB396135 A GB 396135A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acid
- yeast
- adenosine
- temperature
- phosphoric acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
Landscapes
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Yeast adenylic acid (adenosine triphosphoric acid) is converted into muscle adenylic acid (an adenosine phosphoric acid) by hydrolysis at a temperature of 10-50 DEG C. The starting material or crude extract containing it is treated with a hydrolysing agent such as barium hydroxide, caustic soda or mineral acid solution at ordinary or slightly raised temperature, a precipitant then added and the product separated from the precipitate. The adenosine phosphoric acid thus obtained is useful in the therapy of the circulation of the blood. Examples are given. The starting material may be prepared by (1) extracting yeast in the cold with trichloracetic acid, mixing with mercury acetate under feebly alkaline conditions, decomposing with hydrogen sulphide and precipitating the adenosine triphosphoric acid as its calcium salt using calcium chloride and alcohol; (2) treating with water plasmolysates obtained at a low temperature from yeast, eliminating the undissolved constituents, and if desired treating the solution with absorbents, e.g. bentonite, and precipitating with organic solvents, e.g. methyl alcohol, the solution remaining after removing the absorbent; (3) extracting yeast with trichloracetic acid before or after plasmolysis, giving a crude material; (4) plasmolysing yeast with ethyl acetate at a temperature below 15 DEG C. and introducing into boiling water.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE396135X | 1931-02-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB396135A true GB396135A (en) | 1933-08-03 |
Family
ID=6396977
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5263/32A Expired GB396135A (en) | 1931-02-23 | 1932-02-22 | Manufacture of an adenosine phosphoric acid |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB396135A (en) |
-
1932
- 1932-02-22 GB GB5263/32A patent/GB396135A/en not_active Expired
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