GB2456284B - Ion transfer arrangement - Google Patents
Ion transfer arrangementInfo
- Publication number
- GB2456284B GB2456284B GB0909034.1A GB0909034A GB2456284B GB 2456284 B GB2456284 B GB 2456284B GB 0909034 A GB0909034 A GB 0909034A GB 2456284 B GB2456284 B GB 2456284B
- Authority
- GB
- United Kingdom
- Prior art keywords
- ion transfer
- transfer arrangement
- arrangement
- ion
- transfer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/06—Electron- or ion-optical arrangements
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/06—Electron- or ion-optical arrangements
- H01J49/062—Ion guides
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J3/00—Details of electron-optical or ion-optical arrangements or of ion traps common to two or more basic types of discharge tubes or lamps
- H01J3/14—Arrangements for focusing or reflecting ray or beam
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Electron Tubes For Measurement (AREA)
- Sampling And Sample Adjustment (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85773706P | 2006-11-07 | 2006-11-07 | |
| US11/833,209 US20090283674A1 (en) | 2006-11-07 | 2007-08-02 | Efficient Atmospheric Pressure Interface for Mass Spectrometers and Method |
| PCT/EP2007/009642 WO2008061628A2 (en) | 2006-11-07 | 2007-11-07 | Ion transfer arrangement |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| GB0909034D0 GB0909034D0 (en) | 2009-07-01 |
| GB2456284A GB2456284A (en) | 2009-07-15 |
| GB2456284B true GB2456284B (en) | 2012-10-17 |
Family
ID=39321490
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB0909034.1A Expired - Fee Related GB2456284B (en) | 2006-11-07 | 2007-11-07 | Ion transfer arrangement |
| GB0909035.8A Expired - Fee Related GB2456720B (en) | 2006-11-07 | 2007-11-07 | Ion transfer arrangement |
| GB0909032A Expired - Fee Related GB2456283B (en) | 2006-11-07 | 2007-11-07 | Ion transfer arrangement |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB0909035.8A Expired - Fee Related GB2456720B (en) | 2006-11-07 | 2007-11-07 | Ion transfer arrangement |
| GB0909032A Expired - Fee Related GB2456283B (en) | 2006-11-07 | 2007-11-07 | Ion transfer arrangement |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US20090283674A1 (cg-RX-API-DMAC7.html) |
| JP (4) | JP5011393B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN102768936A (cg-RX-API-DMAC7.html) |
| CA (3) | CA2668829C (cg-RX-API-DMAC7.html) |
| DE (3) | DE112007002686B4 (cg-RX-API-DMAC7.html) |
| GB (3) | GB2456284B (cg-RX-API-DMAC7.html) |
| WO (3) | WO2008055668A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7982183B2 (en) * | 2006-11-07 | 2011-07-19 | Thermo Fisher Scientific (Bremen) Gmbh | Ion transfer tube with spatially alternating DC fields |
| US20090283674A1 (en) * | 2006-11-07 | 2009-11-19 | Reinhold Pesch | Efficient Atmospheric Pressure Interface for Mass Spectrometers and Method |
| EP2281297B1 (en) * | 2008-05-30 | 2019-01-16 | DH Technologies Development Pte. Ltd. | Method and system for vacuum driven differential mobility spectrometer/mass spectrometer interface with adjustable resolution and selectivity |
| GB0817115D0 (en) * | 2008-09-18 | 2008-10-29 | Micromass Ltd | Mass spectrometer |
| US8410431B2 (en) * | 2008-10-13 | 2013-04-02 | Purdue Research Foundation | Systems and methods for transfer of ions for analysis |
| US7915580B2 (en) * | 2008-10-15 | 2011-03-29 | Thermo Finnigan Llc | Electro-dynamic or electro-static lens coupled to a stacked ring ion guide |
| GB0907619D0 (en) | 2009-05-01 | 2009-06-10 | Shimadzu Res Lab Europe Ltd | Ion analysis apparatus and method of use |
| US8389930B2 (en) * | 2010-04-30 | 2013-03-05 | Agilent Technologies, Inc. | Input port for mass spectrometers that is adapted for use with ion sources that operate at atmospheric pressure |
| US8710454B2 (en) * | 2011-01-04 | 2014-04-29 | Lawrence Livermore National Security, Llc | High gradient lens for charged particle beam |
| GB201109384D0 (en) * | 2011-06-03 | 2011-07-20 | Micromass Ltd | Sampling with increased efficiency |
| CN104254901B (zh) | 2011-12-28 | 2018-05-04 | 英国质谱有限公司 | 碰撞离子发生器和分离器 |
| US9230790B2 (en) * | 2011-12-30 | 2016-01-05 | Dh Technologies Development Pte. Ltd. | DC ion funnels |
| US8779353B2 (en) * | 2012-01-11 | 2014-07-15 | Bruker Daltonics, Inc. | Ion guide and electrode for its assembly |
| GB2498816A (en) | 2012-01-27 | 2013-07-31 | Edwards Ltd | Vacuum pump |
| EP2631930B1 (en) * | 2012-02-21 | 2017-03-29 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Device for transferring ions from high to low pressure atmosphere, system and use |
| WO2013184320A1 (en) | 2012-06-06 | 2013-12-12 | Purdue Research Foundation | Ion focusing |
| GB2517670B (en) * | 2013-03-15 | 2020-04-29 | Smiths Detection Watford Ltd | Ion modification |
| CN104282525A (zh) * | 2013-07-01 | 2015-01-14 | 中国科学院大连化学物理研究所 | 一种大气压下的离子聚焦传输透镜 |
| GB2531193B (en) * | 2013-08-02 | 2020-07-29 | Hitachi High Tech Corp | Mass spectrometer |
| US8952326B1 (en) * | 2013-11-04 | 2015-02-10 | Agilent Technologies, Inc. | Atmospheric pressure interface with improved ion transfer for spectrometry, and related systems and methods |
| WO2015101821A1 (en) * | 2013-12-31 | 2015-07-09 | Dh Technologies Development Pte. Ltd. | Vacuum dms with high efficiency ion guides |
| CA2932661A1 (en) * | 2013-12-31 | 2015-07-09 | Dh Technologies Development Pte. Ltd. | Jet injector inlet for a differential mobility spectrometer |
| WO2015101823A1 (en) * | 2013-12-31 | 2015-07-09 | Dh Technologies Development Pte. Ltd. | Lens pulsing apparatus and method |
| US9558925B2 (en) * | 2014-04-18 | 2017-01-31 | Battelle Memorial Institute | Device for separating non-ions from ions |
| JP6295150B2 (ja) * | 2014-07-07 | 2018-03-14 | 株式会社日立ハイテクノロジーズ | 質量分析装置 |
| US9564305B2 (en) * | 2014-07-29 | 2017-02-07 | Smiths Detection Inc. | Ion funnel for efficient transmission of low mass-to-charge ratio ions with reduced gas flow at the exit |
| GB2531292B (en) * | 2014-10-14 | 2019-06-12 | Smiths Detection Watford Ltd | Method and apparatus |
| CN105679636B (zh) | 2014-11-19 | 2018-04-10 | 株式会社岛津制作所 | 聚焦离子导引装置及质谱分析装置 |
| CN104599933B (zh) * | 2015-01-08 | 2017-12-15 | 聚光科技(杭州)股份有限公司 | 一种电子电离源 |
| US10607826B2 (en) | 2015-07-28 | 2020-03-31 | University Of Florida Research Foundation, Incorporated | Atmospheric pressure ion guide |
| WO2017034972A1 (en) | 2015-08-21 | 2017-03-02 | PharmaCadence Analytical Services, LLC | Novel methods of evaluating performance of an atmospheric pressure ionization system |
| US10317364B2 (en) | 2015-10-07 | 2019-06-11 | Battelle Memorial Institute | Method and apparatus for ion mobility separations utilizing alternating current waveforms |
| US10103014B2 (en) * | 2016-09-05 | 2018-10-16 | Agilent Technologies, Inc. | Ion transfer device for mass spectrometry |
| JP6811682B2 (ja) * | 2017-06-08 | 2021-01-13 | 株式会社日立ハイテク | 質量分析装置およびノズル部材 |
| US10541122B2 (en) | 2017-06-13 | 2020-01-21 | Mks Instruments, Inc. | Robust ion source |
| US10692710B2 (en) * | 2017-08-16 | 2020-06-23 | Battelle Memorial Institute | Frequency modulated radio frequency electric field for ion manipulation |
| EP3692564A1 (en) | 2017-10-04 | 2020-08-12 | Battelle Memorial Institute | Methods and systems for integrating ion manipulation devices |
| GB201810826D0 (en) * | 2018-06-01 | 2018-08-15 | Micromass Ltd | Ion guide |
| CN109192648B (zh) * | 2018-08-09 | 2023-09-15 | 金华职业技术学院 | 一种自由基光产物测试方法 |
| US11791149B2 (en) | 2019-07-31 | 2023-10-17 | Agilent Technologies, Inc. | Axially progressive lens for transporting charged particles |
| CN110957198B (zh) * | 2019-12-12 | 2021-03-05 | 中国科学院化学研究所 | 一种逆压梯度传输的离子透镜系统 |
| DE102020111820A1 (de) | 2020-04-30 | 2021-11-04 | Friedrich-Alexander-Universität Erlangen - Nürnberg | Elektrodenstruktur zum Führen eines Strahls geladener Teilchen |
Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6107628A (en) * | 1998-06-03 | 2000-08-22 | Battelle Memorial Institute | Method and apparatus for directing ions and other charged particles generated at near atmospheric pressures into a region under vacuum |
| US6483109B1 (en) * | 1999-08-26 | 2002-11-19 | University Of New Hampshire | Multiple stage mass spectrometer |
| US6504150B1 (en) * | 1999-06-11 | 2003-01-07 | Perseptive Biosystems, Inc. | Method and apparatus for determining molecular weight of labile molecules |
| US20030136905A1 (en) * | 2001-12-06 | 2003-07-24 | Bruker Daltonik Gmbh | Ion-guide systems |
| US6781117B1 (en) * | 2002-05-30 | 2004-08-24 | Ross C Willoughby | Efficient direct current collision and reaction cell |
| US6906322B2 (en) * | 2001-03-29 | 2005-06-14 | Wisconsin Alumni Research Foundation | Charged particle source with droplet control for mass spectrometry |
| WO2005067000A2 (en) * | 2004-01-09 | 2005-07-21 | Ms Horizons Limited | Ion extraction devices and methods of selectively extracting ions |
| US6943347B1 (en) * | 2002-10-18 | 2005-09-13 | Ross Clark Willoughby | Laminated tube for the transport of charged particles contained in a gaseous medium |
| US20060097156A1 (en) * | 2002-09-25 | 2006-05-11 | Roger Guevremont | Faims apparatus and method for separting ions |
| GB2437829A (en) * | 2006-04-28 | 2007-11-07 | Micromass Ltd | A mass analyzer utilising a plurality of axial pseudo-potential barriers |
Family Cites Families (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2883568A (en) * | 1957-06-25 | 1959-04-21 | Rca Corp | Apparatus for producing thermallycool charged particles |
| NL278803A (cg-RX-API-DMAC7.html) * | 1961-05-25 | |||
| US4542293A (en) * | 1983-04-20 | 1985-09-17 | Yale University | Process and apparatus for changing the energy of charged particles contained in a gaseous medium |
| US4556794A (en) * | 1985-01-30 | 1985-12-03 | Hughes Aircraft Company | Secondary ion collection and transport system for ion microprobe |
| US4935624A (en) * | 1987-09-30 | 1990-06-19 | Cornell Research Foundation, Inc. | Thermal-assisted electrospray interface (TAESI) for LC/MS |
| US5095208A (en) * | 1988-06-24 | 1992-03-10 | Hitachi, Ltd. | Charged particle generating device and focusing lens therefor |
| US4977320A (en) * | 1990-01-22 | 1990-12-11 | The Rockefeller University | Electrospray ionization mass spectrometer with new features |
| US5095206A (en) * | 1990-06-01 | 1992-03-10 | Environmental Technologies Group, Inc. | Method and apparatus for improving the specificity of an ion mobility spectrometer utillizing sulfur dioxide dopant chemistry |
| US5157260A (en) * | 1991-05-17 | 1992-10-20 | Finnian Corporation | Method and apparatus for focusing ions in viscous flow jet expansion region of an electrospray apparatus |
| US5245186A (en) * | 1991-11-18 | 1993-09-14 | The Rockefeller University | Electrospray ion source for mass spectrometry |
| US5331159A (en) * | 1993-01-22 | 1994-07-19 | Hewlett Packard Company | Combined electrospray/particle beam liquid chromatography/mass spectrometer |
| JPH07130325A (ja) | 1993-10-29 | 1995-05-19 | Hitachi Ltd | 質量分析装置 |
| US5689111A (en) * | 1995-08-10 | 1997-11-18 | Analytica Of Branford, Inc. | Ion storage time-of-flight mass spectrometer |
| DE19515271C2 (de) * | 1995-04-26 | 1999-09-02 | Bruker Daltonik Gmbh | Vorrichtung für den gasgeführten Transport von Ionen durch ein Kapillarrohr |
| JP2953344B2 (ja) * | 1995-04-28 | 1999-09-27 | 株式会社島津製作所 | 液体クロマトグラフ質量分析装置 |
| DE19520276C2 (de) * | 1995-06-02 | 1999-08-26 | Bruker Daltonik Gmbh | Vorrichtung für die Einführung von Ionen in ein Massenspektrometer |
| JPH0943201A (ja) * | 1995-07-27 | 1997-02-14 | Shimadzu Corp | 液体クロマトグラフ質量分析装置 |
| GB9525507D0 (en) * | 1995-12-14 | 1996-02-14 | Fisons Plc | Electrospray and atmospheric pressure chemical ionization mass spectrometer and ion source |
| JPH10112280A (ja) * | 1996-10-08 | 1998-04-28 | Jeol Ltd | イオン源 |
| US5879461A (en) * | 1997-04-21 | 1999-03-09 | Brooks Automation, Inc. | Metered gas control in a substrate processing apparatus |
| US5756995A (en) * | 1997-07-09 | 1998-05-26 | The United States Of America As Represented By The Secretary Of The Army | Ion interface for mass spectrometer |
| US6271529B1 (en) * | 1997-12-01 | 2001-08-07 | Ebara Corporation | Ion implantation with charge neutralization |
| JPH11307040A (ja) * | 1998-04-23 | 1999-11-05 | Jeol Ltd | イオンガイド |
| JP3571546B2 (ja) * | 1998-10-07 | 2004-09-29 | 日本電子株式会社 | 大気圧イオン化質量分析装置 |
| US6486469B1 (en) * | 1999-10-29 | 2002-11-26 | Agilent Technologies, Inc. | Dielectric capillary high pass ion filter |
| JP3743240B2 (ja) * | 1999-12-24 | 2006-02-08 | 株式会社日立製作所 | 液体クロマトグラフ質量分析装置 |
| JP2001343364A (ja) * | 2000-06-05 | 2001-12-14 | Sumitomo Heavy Ind Ltd | 固体中の特定原子の検出装置 |
| JP2001349871A (ja) * | 2000-06-09 | 2001-12-21 | Sumitomo Heavy Ind Ltd | 固体中の特定原子の検出装置 |
| US6417511B1 (en) * | 2000-07-17 | 2002-07-09 | Agilent Technologies, Inc. | Ring pole ion guide apparatus, systems and method |
| GB2375653B (en) * | 2001-02-22 | 2004-11-10 | Bruker Daltonik Gmbh | Travelling field for packaging ion beams |
| GB2404784B (en) * | 2001-03-23 | 2005-06-22 | Thermo Finnigan Llc | Mass spectrometry method and apparatus |
| US6583408B2 (en) | 2001-05-18 | 2003-06-24 | Battelle Memorial Institute | Ionization source utilizing a jet disturber in combination with an ion funnel and method of operation |
| US6723986B2 (en) * | 2002-03-15 | 2004-04-20 | Agilent Technologies, Inc. | Apparatus for manipulation of ions and methods of making apparatus |
| JP3791479B2 (ja) | 2002-09-17 | 2006-06-28 | 株式会社島津製作所 | イオンガイド |
| US7084394B2 (en) | 2002-09-25 | 2006-08-01 | Ionalytics Corporation | FAIMS apparatus and method for separating ions |
| CA2470452C (en) * | 2003-06-09 | 2017-10-03 | Ionics Mass Spectrometry Group, Inc. | Mass spectrometer interface |
| JP2005085538A (ja) * | 2003-09-05 | 2005-03-31 | Doshisha | 質量分離装置および質量分離方法 |
| JP2005259477A (ja) * | 2004-03-11 | 2005-09-22 | Hitachi High-Technologies Corp | エレクトロスプレイイオン化質量分析装置 |
| JP4285283B2 (ja) | 2004-03-11 | 2009-06-24 | 株式会社島津製作所 | 質量分析装置 |
| JP4193734B2 (ja) | 2004-03-11 | 2008-12-10 | 株式会社島津製作所 | 質量分析装置 |
| DE102004048496B4 (de) * | 2004-10-05 | 2008-04-30 | Bruker Daltonik Gmbh | Ionenführung mit HF-Blendenstapeln |
| US7259369B2 (en) * | 2005-08-22 | 2007-08-21 | Battelle Energy Alliance, Llc | Dual mode ion mobility spectrometer and method for ion mobility spectrometry |
| US7700913B2 (en) * | 2006-03-03 | 2010-04-20 | Ionsense, Inc. | Sampling system for use with surface ionization spectroscopy |
| US20090283674A1 (en) * | 2006-11-07 | 2009-11-19 | Reinhold Pesch | Efficient Atmospheric Pressure Interface for Mass Spectrometers and Method |
| US7982183B2 (en) * | 2006-11-07 | 2011-07-19 | Thermo Fisher Scientific (Bremen) Gmbh | Ion transfer tube with spatially alternating DC fields |
-
2007
- 2007-08-02 US US11/833,209 patent/US20090283674A1/en not_active Abandoned
- 2007-11-07 CA CA2668829A patent/CA2668829C/en not_active Expired - Fee Related
- 2007-11-07 CA CA2668762A patent/CA2668762C/en not_active Expired - Fee Related
- 2007-11-07 DE DE112007002686.3T patent/DE112007002686B4/de not_active Expired - Fee Related
- 2007-11-07 GB GB0909034.1A patent/GB2456284B/en not_active Expired - Fee Related
- 2007-11-07 US US12/513,944 patent/US8148679B2/en active Active
- 2007-11-07 US US12/513,954 patent/US8148680B2/en active Active
- 2007-11-07 WO PCT/EP2007/009641 patent/WO2008055668A2/en not_active Ceased
- 2007-11-07 GB GB0909035.8A patent/GB2456720B/en not_active Expired - Fee Related
- 2007-11-07 JP JP2009535621A patent/JP5011393B2/ja not_active Expired - Fee Related
- 2007-11-07 WO PCT/EP2007/009640 patent/WO2008055667A2/en not_active Ceased
- 2007-11-07 JP JP2009535623A patent/JP2010508643A/ja active Pending
- 2007-11-07 DE DE112007002661.8T patent/DE112007002661B4/de not_active Expired - Fee Related
- 2007-11-07 JP JP2009535622A patent/JP5197618B2/ja not_active Expired - Fee Related
- 2007-11-07 CN CN201210111145XA patent/CN102768936A/zh active Pending
- 2007-11-07 WO PCT/EP2007/009642 patent/WO2008061628A2/en not_active Ceased
- 2007-11-07 GB GB0909032A patent/GB2456283B/en not_active Expired - Fee Related
- 2007-11-07 CA CA2668763A patent/CA2668763C/en not_active Expired - Fee Related
- 2007-11-07 DE DE112007002694T patent/DE112007002694T5/de not_active Ceased
-
2012
- 2012-02-29 JP JP2012043734A patent/JP5575165B2/ja not_active Expired - Fee Related
- 2012-03-06 US US13/413,568 patent/US8642949B2/en active Active
Patent Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6107628A (en) * | 1998-06-03 | 2000-08-22 | Battelle Memorial Institute | Method and apparatus for directing ions and other charged particles generated at near atmospheric pressures into a region under vacuum |
| US6504150B1 (en) * | 1999-06-11 | 2003-01-07 | Perseptive Biosystems, Inc. | Method and apparatus for determining molecular weight of labile molecules |
| US6483109B1 (en) * | 1999-08-26 | 2002-11-19 | University Of New Hampshire | Multiple stage mass spectrometer |
| US6906322B2 (en) * | 2001-03-29 | 2005-06-14 | Wisconsin Alumni Research Foundation | Charged particle source with droplet control for mass spectrometry |
| US20030136905A1 (en) * | 2001-12-06 | 2003-07-24 | Bruker Daltonik Gmbh | Ion-guide systems |
| US6781117B1 (en) * | 2002-05-30 | 2004-08-24 | Ross C Willoughby | Efficient direct current collision and reaction cell |
| US20060097156A1 (en) * | 2002-09-25 | 2006-05-11 | Roger Guevremont | Faims apparatus and method for separting ions |
| US6943347B1 (en) * | 2002-10-18 | 2005-09-13 | Ross Clark Willoughby | Laminated tube for the transport of charged particles contained in a gaseous medium |
| WO2005067000A2 (en) * | 2004-01-09 | 2005-07-21 | Ms Horizons Limited | Ion extraction devices and methods of selectively extracting ions |
| GB2437829A (en) * | 2006-04-28 | 2007-11-07 | Micromass Ltd | A mass analyzer utilising a plurality of axial pseudo-potential barriers |
Non-Patent Citations (1)
| Title |
|---|
| Journal of the American Society for Mass Spectrometry, Vol. 7, No. 1, 1 January 1996, pages 101-106 * |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 20201107 |