GB2411354B - Use of Scutellaria for the treatment of viral infections - Google Patents

Use of Scutellaria for the treatment of viral infections

Info

Publication number
GB2411354B
GB2411354B GB0404327A GB0404327A GB2411354B GB 2411354 B GB2411354 B GB 2411354B GB 0404327 A GB0404327 A GB 0404327A GB 0404327 A GB0404327 A GB 0404327A GB 2411354 B GB2411354 B GB 2411354B
Authority
GB
United Kingdom
Prior art keywords
scutellaria
treatment
viral infections
infections
viral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB0404327A
Other languages
English (en)
Other versions
GB0404327D0 (en
GB2411354A (en
Inventor
Shouming Zhong
Hongwen Yu
Robert Miller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Phynova Ltd
Original Assignee
Phynova Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phynova Ltd filed Critical Phynova Ltd
Priority to GB0608398A priority Critical patent/GB2425476A/en
Priority to GB0404327A priority patent/GB2411354B/en
Priority to GB0608399A priority patent/GB2425477B/en
Publication of GB0404327D0 publication Critical patent/GB0404327D0/en
Priority to EP05717795A priority patent/EP1734976A1/en
Priority to CNA2005800060853A priority patent/CN1925863A/zh
Priority to AU2005216697A priority patent/AU2005216697A1/en
Priority to JP2007500294A priority patent/JP2007524709A/ja
Priority to US10/590,287 priority patent/US20080038382A1/en
Priority to PCT/GB2005/000714 priority patent/WO2005082388A1/en
Publication of GB2411354A publication Critical patent/GB2411354A/en
Application granted granted Critical
Publication of GB2411354B publication Critical patent/GB2411354B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/35—Caprifoliaceae (Honeysuckle family)
    • A61K36/355—Lonicera (honeysuckle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539—Scutellaria (skullcap)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634—Forsythia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)
GB0404327A 2004-02-27 2004-02-27 Use of Scutellaria for the treatment of viral infections Expired - Fee Related GB2411354B (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
GB0608398A GB2425476A (en) 2004-02-27 2004-02-27 Multi-herb medicament for the treatment of SARS
GB0404327A GB2411354B (en) 2004-02-27 2004-02-27 Use of Scutellaria for the treatment of viral infections
GB0608399A GB2425477B (en) 2004-02-27 2004-02-27 Extract of Scutellaria for the treatment of RSV
JP2007500294A JP2007524709A (ja) 2004-02-27 2005-02-25 Ｓａｒｓを治療するためのスクテラリア抽出物
CNA2005800060853A CN1925863A (zh) 2004-02-27 2005-02-25 用于治疗sars的黄芩属提取物
AU2005216697A AU2005216697A1 (en) 2004-02-27 2005-02-25 Extracts of Scutellaria for the treatment of SARS
EP05717795A EP1734976A1 (en) 2004-02-27 2005-02-25 Extracts of scutellaria for the treatment of sars
US10/590,287 US20080038382A1 (en) 2004-02-27 2005-02-25 Extracts of Scutellaria for the Treatment of Sars
PCT/GB2005/000714 WO2005082388A1 (en) 2004-02-27 2005-02-25 Extracts of scutellaria for the treatment of sars

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB0404327A GB2411354B (en) 2004-02-27 2004-02-27 Use of Scutellaria for the treatment of viral infections

Publications (3)

Publication Number Publication Date
GB0404327D0 GB0404327D0 (en) 2004-03-31
GB2411354A GB2411354A (en) 2005-08-31
GB2411354B true GB2411354B (en) 2008-02-20

Family

ID=32050939

Family Applications (2)

Application Number Title Priority Date Filing Date
GB0404327A Expired - Fee Related GB2411354B (en) 2004-02-27 2004-02-27 Use of Scutellaria for the treatment of viral infections
GB0608398A Withdrawn GB2425476A (en) 2004-02-27 2004-02-27 Multi-herb medicament for the treatment of SARS

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB0608398A Withdrawn GB2425476A (en) 2004-02-27 2004-02-27 Multi-herb medicament for the treatment of SARS

Country Status (7)

Country Link
US (1) US20080038382A1 (enExample)
EP (1) EP1734976A1 (enExample)
JP (1) JP2007524709A (enExample)
CN (1) CN1925863A (enExample)
AU (1) AU2005216697A1 (enExample)
GB (2) GB2411354B (enExample)
WO (1) WO2005082388A1 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2006100710A1 (ja) * 2005-03-18 2008-08-28 太陽化学株式会社 重症急性呼吸器症候群の予防および治療用組成物
CN101701245B (zh) * 2009-10-21 2013-06-19 中国科学院生物物理研究所 从中药中筛选sars冠状病毒主蛋白酶抑制剂的方法
CN103720650A (zh) * 2014-01-17 2014-04-16 中国药科大学 一种具有抗流感病毒作用的黄芩苷注射剂
CN104800318A (zh) * 2014-01-26 2015-07-29 天津嘉创生物科技有限公司 治疗畜禽上呼吸道感染的中药组合物及其制备方法
CN105372377B (zh) * 2014-08-07 2017-09-29 富力 一种原料药连翘苷的质量检测方法
CN104356185B (zh) * 2014-09-26 2017-05-17 山西大学 一种提取黄芩苷的方法
CN105168807B (zh) * 2015-10-16 2019-04-19 大连民族大学 治疗猪蓝耳病的中药组合物及其制备方法
CN113209164B (zh) * 2020-02-06 2023-01-20 中国科学院上海药物研究所 黄芩、连翘、金银花主要成分及其组合物在抗冠状病毒中的应用
CN113244211B (zh) * 2020-02-07 2023-04-07 中国科学院上海药物研究所 黄芩素、黄芩苷用于制备冠状病毒SARS-CoV-2的3CL蛋白酶的抑制剂的用途
CN113244212B (zh) * 2020-02-10 2023-05-05 中国医学科学院药物研究所 黄芩素在制备预防和/或治疗新型冠状病毒感染疾病的药物中的应用
CN113368121A (zh) * 2020-03-09 2021-09-10 吉林亚泰制药股份有限公司 抗冠状病毒的连翘苷和连翘脂素组合物
WO2021188614A1 (en) * 2020-03-18 2021-09-23 Dejia Harmony Llc Composition, methods of making and using for treating a viral infection, including coronavirus infection
AU2021281159B2 (en) * 2020-05-29 2024-09-19 Vedicinals India Private Limited A composition for management of COVID-19 and associated disorders
RU2741714C1 (ru) * 2020-08-13 2021-01-28 Федеральное бюджетное учреждение науки "Государственный научный центр вирусологии и биотехнологии "Вектор" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека (ФБУН ГНЦ ВБ "Вектор" Роспотребнадзора) Ингибитор репликации коронавируса SARS-CoV-2 на основе водного экстракта гриба Inonotus obliquus
US20220054575A1 (en) * 2020-08-19 2022-02-24 Natreon, Inc. Protection against coronavirus infection by extracts and extract components
RU2747018C1 (ru) * 2020-10-14 2021-04-23 Федеральное бюджетное учреждение науки "Государственный научный центр вирусологии и биотехнологии "Вектор" Федеральной службы по надзору в сфере зашиты прав потребителей и благополучия человека (ФБУН ГНЦ ВБ "Вектор" Роспотребнадзора) Ингибитор репликации коронавируса SARS-CoV-2 на основе меланина из гриба Inonotus obliquus
RU2752872C1 (ru) * 2020-11-03 2021-08-11 Федеральное бюджетное учреждение науки "Государственный научный центр вирусологии и биотехнологии "Вектор" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека (ФБУН ГНЦ ВБ "Вектор" Роспотребнадзора) Ингибитор репликации коронавируса SARS-CoV-2 на основе гуминовых веществ
CN113813271B (zh) * 2020-11-09 2023-12-12 首都医科大学 连翘酯苷f在制备抗冠状病毒产品中的应用
CN118477064B (zh) * 2024-05-14 2024-12-20 南阳师范学院 黄芩素在抗大口黑鲈弹状病毒方面的应用

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5411733A (en) * 1992-04-27 1995-05-02 Hozumi; Toyoharu Antiviral agent containing crude drug
US6083921A (en) * 1998-01-12 2000-07-04 Xu; Kai Jian Pharmaceutical compositions and method of using same
WO2002060379A2 (en) * 2000-10-25 2002-08-08 National Engineering Research Center For Traditional Chinese Medicine Composition comprising extracts of flos lonicerae, fructus forsythiae and radix scutellariae, uses and preparation thereof
CN1448179A (zh) * 2003-05-06 2003-10-15 哈药集团中药二厂 注射用双黄连在制备用于治疗严重急性呼吸道综合症的药物中的应用
CN1476886A (zh) * 2003-07-01 2004-02-25 陈淀炜 抗癌抗sars保健茶

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1470262A (zh) * 2002-07-23 2004-01-28 北京大学安康药物研究院 一种双黄连制剂及其制备方法
CN1449813A (zh) * 2003-04-29 2003-10-22 兰金初 治疗非典型肺炎的药物
CN1454665A (zh) * 2003-06-02 2003-11-12 丁润泉 一种防治sars病毒的中药
CN1164267C (zh) * 2003-06-02 2004-09-01 中国科学院上海药物研究所 绿原酸的医学用途及它的制剂
CN1238037C (zh) * 2003-06-09 2006-01-25 方文理 治疗肺炎和非典型肺炎的药物
CN1135111C (zh) * 2003-06-13 2004-01-21 胡馨元 抗非典型性肺炎汤

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5411733A (en) * 1992-04-27 1995-05-02 Hozumi; Toyoharu Antiviral agent containing crude drug
US6083921A (en) * 1998-01-12 2000-07-04 Xu; Kai Jian Pharmaceutical compositions and method of using same
WO2002060379A2 (en) * 2000-10-25 2002-08-08 National Engineering Research Center For Traditional Chinese Medicine Composition comprising extracts of flos lonicerae, fructus forsythiae and radix scutellariae, uses and preparation thereof
CN1448179A (zh) * 2003-05-06 2003-10-15 哈药集团中药二厂 注射用双黄连在制备用于治疗严重急性呼吸道综合症的药物中的应用
CN1476886A (zh) * 2003-07-01 2004-02-25 陈淀炜 抗癌抗sars保健茶

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
http://www.itmonline.org/arts/shuang.htm, published September 2003, (Subhuti Dharmanada), pages 1-5, retrieved from the internet August 2006 *
Journal of Ethnopharmacology, Vol. 79, No. 2, 2002, (SHUANG-CHENG MA et al), pages 205-211 *
WPI Abstract Acc. No.2004-063149 [07] & CN 1449818 A (HUXX-I) *
WPI Abstract No. 2004-063145 [07] & CN 1449813 A (LAN JINCHU) *

Also Published As

Publication number Publication date
WO2005082388A1 (en) 2005-09-09
AU2005216697A1 (en) 2005-09-09
US20080038382A1 (en) 2008-02-14
CN1925863A (zh) 2007-03-07
GB0404327D0 (en) 2004-03-31
EP1734976A1 (en) 2006-12-27
GB2411354A (en) 2005-08-31
JP2007524709A (ja) 2007-08-30
GB2425476A (en) 2006-11-01
GB0608398D0 (en) 2006-06-07

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20100227