GB2224207B - Pharmaceutical composition comprising piroxicam and lactose for use in making tablets or capsules - Google Patents

Pharmaceutical composition comprising piroxicam and lactose for use in making tablets or capsules

Info

Publication number
GB2224207B
GB2224207B GB8924286A GB8924286A GB2224207B GB 2224207 B GB2224207 B GB 2224207B GB 8924286 A GB8924286 A GB 8924286A GB 8924286 A GB8924286 A GB 8924286A GB 2224207 B GB2224207 B GB 2224207B
Authority
GB
United Kingdom
Prior art keywords
piroxicam
lactose
capsules
pharmaceutical composition
making tablets
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
GB8924286A
Other languages
English (en)
Other versions
GB8924286D0 (en
GB2224207A (en
Inventor
Pal Fekete
Denes Bezzegh
Istvan Simonyi
Biborka Maroshelyi
Katalin Zukovics
Janos Tombor
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyt Gyogyszervegyeszeti Gyar
Egis Pharmaceuticals PLC
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Egis Pharmaceuticals PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar, Egis Pharmaceuticals PLC filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of GB8924286D0 publication Critical patent/GB8924286D0/en
Publication of GB2224207A publication Critical patent/GB2224207A/en
Application granted granted Critical
Publication of GB2224207B publication Critical patent/GB2224207B/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
GB8924286A 1988-10-28 1989-10-27 Pharmaceutical composition comprising piroxicam and lactose for use in making tablets or capsules Expired - Lifetime GB2224207B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU885621A HU200926B (en) 1988-10-28 1988-10-28 Pharmaceutical composition comprising piroxicam and lactose for use in making tablets or capsules

Publications (3)

Publication Number Publication Date
GB8924286D0 GB8924286D0 (en) 1989-12-13
GB2224207A GB2224207A (en) 1990-05-02
GB2224207B true GB2224207B (en) 1992-06-10

Family

ID=10970484

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8924286A Expired - Lifetime GB2224207B (en) 1988-10-28 1989-10-27 Pharmaceutical composition comprising piroxicam and lactose for use in making tablets or capsules

Country Status (9)

Country Link
JP (1) JPH02172918A (it)
AT (1) AT399277B (it)
CA (1) CA2001673C (it)
DE (1) DE3936112C2 (it)
FR (1) FR2638357B1 (it)
GB (1) GB2224207B (it)
HU (1) HU200926B (it)
IL (1) IL92138A (it)
IT (1) IT1239542B (it)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2642486B2 (ja) * 1989-08-04 1997-08-20 田辺製薬株式会社 難溶性薬物の超微粒子化法
JP2964195B2 (ja) * 1992-04-28 1999-10-18 エスエス製薬株式会社 ピロキシカム錠及びその製造法
DE19603402A1 (de) * 1995-02-24 1996-08-29 Basf Ag Weichgelatinekapseln
AU733032C (en) * 1996-06-14 2002-01-03 Kyowa Hakko Kirin Co., Ltd. Intraorally rapidly disintegrable tablet
JP4568426B2 (ja) * 1998-04-08 2010-10-27 協和発酵キリン株式会社 錠剤の製造方法及び錠剤
JP2000095674A (ja) 1998-09-22 2000-04-04 Sato Pharmaceutical Co Ltd 口腔内崩壊時間短縮化錠剤の製造方法及び装置
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
EP1574215B1 (en) * 2002-12-16 2015-07-15 Kissei Pharmaceutical Co., Ltd. Solid drug for oral use
US8367111B2 (en) 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
US8747895B2 (en) 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
EP2417969A1 (en) 2004-10-21 2012-02-15 Aptalis Pharmatech, Inc. Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
CN101232905B (zh) * 2005-07-25 2013-01-09 大塚制药株式会社 一种用于测量嘧啶代谢能力的口服制剂
CN102958515A (zh) 2009-12-02 2013-03-06 阿普塔利斯制药有限公司 非索非那定微胶囊及含有非索非那定微胶囊的组合物
EP2887066B1 (en) 2012-08-20 2020-08-05 Otsuka Pharmaceutical Co., Ltd. Composition for use in a method for measuring carbohydrate metabolism ability
CN105051533B (zh) 2013-03-15 2019-03-26 大塚制药株式会社 基于脂肪酸燃烧的测定胰岛素抵抗性的方法及用于该方法的组合物

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3591584A (en) * 1968-08-27 1971-07-06 Pfizer Benzothiazine dioxides
GB1308533A (en) * 1969-06-02 1973-02-21 Pfizer Benzothiazine dioxides as anti-thombotic agents
GB2172487A (en) * 1985-03-20 1986-09-24 Nestle Sa Preparation of a composition based on a finely divided active principle of low water solubility

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55129221A (en) * 1979-03-29 1980-10-06 Kaken Pharmaceut Co Ltd Preparation of oral preparation containing hardly soluble medicine
US4350689A (en) * 1980-02-15 1982-09-21 American Cyanamid Company Combinations of agents which give enhanced anti-inflammatory activity
US4434164A (en) * 1981-06-01 1984-02-28 Pfizer Inc. Crystalline benzothiazine dioxide salts
RO88420A (ro) * 1983-04-25 1986-01-30 Pfizer Inc,Us Procedeu pentru prepararea unor saruri bazice de piroxican depuse pe suporturi farmaceutice
DE3419128A1 (de) * 1984-05-23 1985-11-28 Bayer Ag, 5090 Leverkusen Dihydropyridinpraeparate und verfahren zu ihrer herstellung
ES545221A0 (es) * 1985-07-02 1986-01-01 Ferrer Int Procedimiento de obtencion de particulas de 4-hidroxi-2-me- til-n-2-piridil-2h-1,2-benzotiazina-3-carboxamida-1,1-dioxi-do(piroxicam) recubiertas

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3591584A (en) * 1968-08-27 1971-07-06 Pfizer Benzothiazine dioxides
GB1308533A (en) * 1969-06-02 1973-02-21 Pfizer Benzothiazine dioxides as anti-thombotic agents
GB2172487A (en) * 1985-03-20 1986-09-24 Nestle Sa Preparation of a composition based on a finely divided active principle of low water solubility

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
The Extra Pharmacopoeia (Martindale), 28th Ed., pp54 and 275-276. *
The Pharmaceutical Codex, 11th Ed., pub: The Pharmaceutical Press, 1979; pp483 and 726-727. *
The Theory and Practice of Industrial Pharmacy, 2nd Ed., Lachman, Lieberman and Kanig, pp101-103. *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
US8357396B2 (en) 1996-06-14 2013-01-22 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets

Also Published As

Publication number Publication date
FR2638357A1 (fr) 1990-05-04
GB8924286D0 (en) 1989-12-13
HUT51143A (en) 1990-04-28
ATA247489A (de) 1994-09-15
CA2001673A1 (en) 1990-04-28
FR2638357B1 (fr) 1993-10-22
IT1239542B (it) 1993-11-05
CA2001673C (en) 1996-08-27
IT8922164A1 (it) 1991-04-27
IL92138A0 (en) 1990-07-12
HU200926B (en) 1990-09-28
DE3936112A1 (de) 1990-05-31
JPH02172918A (ja) 1990-07-04
IL92138A (en) 1994-08-26
DE3936112C2 (de) 1999-02-18
AT399277B (de) 1995-04-25
GB2224207A (en) 1990-05-02
IT8922164A0 (it) 1989-10-27

Similar Documents

Publication Publication Date Title
GB2224207B (en) Pharmaceutical composition comprising piroxicam and lactose for use in making tablets or capsules
NZ231247A (en) Two-layer pharmaceutical tablet containing analgesic and decongestant
GB2225764B (en) Improvements in and relating to drug capsules
NZ233320A (en) 3-substituted-2-oxo-indole derivatives and pharmaceutical compositions
NZ231445A (en) Quinuclidine derivatives and pharmaceutical compositions
IL95351A0 (en) 17beta-acyl-4-aza-5alpha-androst-1-en-3-ones and pharmaceutical compositions containing them
NZ220020A (en) 1-hydroxy-2-pyridones and pharmaceutical composition
NZ231487A (en) Pyridin-2-yl piperazine derivatives and pharmaceutical compositions
EP0304802A3 (en) Pharmaceutical composition and the use thereof
NZ233790A (en) Benzocycloalkane derivatives and pharmaceutical compositions
GB9010561D0 (en) Enzymes and their use in drug detection
NZ233011A (en) Thieno-triazole-diazepine and pharmaceutical compositions
EP0347748A3 (en) Pharmaceutical granules and tablets made therefrom
NZ226450A (en) Crystalline-1-carbacephalosporin and pharmaceutical compositions
GR900300044T1 (en) Use of monosubstitute selenium compounds in the preparation of a pharmaceutical, pharmaceutical and preparation thereof
GB8808758D0 (en) Nutritional and medicinal compositions
IL90065A0 (en) 1alpha-hydroxyvitamin-d homologs and pharmaceutical compositions containing them
NZ239222A (en) Pharmaceutical capsules and tablets containing ifosfamide
IL89145A (en) 5-substituted ornithine derivatives and pharmaceutical compositions containing them
GB2221464B (en) Oxaza heterocycles and their use in pharmaceutical compositions
IL91451A0 (en) Pharmaceutical compositions comprising azapiron compounds and their use in the treatment of addiction
IL93986A0 (en) Improvements in and relating to pharmaceutical formulations
NZ228789A (en) Benzothiazepin-4-one derivatives and pharmaceutical compositions; processes for preparation
IL92650A0 (en) Polyhydroxybenzyloxypropanolamides and pharmaceutical compositions containing them
GB2223014B (en) Heterocyclic compounds and their use in pharmaceutical compositions

Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20031027