JPS55129221A - Preparation of oral preparation containing hardly soluble medicine - Google Patents

Preparation of oral preparation containing hardly soluble medicine

Info

Publication number
JPS55129221A
JPS55129221A JP3629879A JP3629879A JPS55129221A JP S55129221 A JPS55129221 A JP S55129221A JP 3629879 A JP3629879 A JP 3629879A JP 3629879 A JP3629879 A JP 3629879A JP S55129221 A JPS55129221 A JP S55129221A
Authority
JP
Japan
Prior art keywords
preparation
soluble
hardly soluble
soluble medicine
disintegrant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP3629879A
Other languages
Japanese (ja)
Inventor
Kenji Kono
Takashi Ogino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kaken Pharmaceutical Co Ltd
Original Assignee
Kaken Pharmaceutical Co Ltd
Kaken Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kaken Pharmaceutical Co Ltd, Kaken Chemical Co Ltd filed Critical Kaken Pharmaceutical Co Ltd
Priority to JP3629879A priority Critical patent/JPS55129221A/en
Publication of JPS55129221A publication Critical patent/JPS55129221A/en
Pending legal-status Critical Current

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  • Medicinal Preparation (AREA)

Abstract

PURPOSE: To prepare the title preparation having improved solubility and absorbability through the digestive tracts, by compounding powdered hardly soluble medicine with a disintegrant and a water-soluble polymer.
CONSTITUTION: A hardly soluble medicine (e.g. indomethacin, phenacetin, diazepam, proglumide, spironolactone, etc.) is pulverized, and mixed with 2W15wt% of a disintegrant (e.g. corn starch, carboxymethyl cellulose calcium, etc.) and 5W30wt% of a water-soluble polymer (e.g. polyvinyl pyrrolidone, polyethylene glycol, etc.), to obtain the title preparatipn. The preparation thus obtained is a swellable and soluble preparation having the characteristics of soluble-type preparation and that of swelling and dispersing-type preparation.
COPYRIGHT: (C)1980,JPO&Japio
JP3629879A 1979-03-29 1979-03-29 Preparation of oral preparation containing hardly soluble medicine Pending JPS55129221A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP3629879A JPS55129221A (en) 1979-03-29 1979-03-29 Preparation of oral preparation containing hardly soluble medicine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3629879A JPS55129221A (en) 1979-03-29 1979-03-29 Preparation of oral preparation containing hardly soluble medicine

Publications (1)

Publication Number Publication Date
JPS55129221A true JPS55129221A (en) 1980-10-06

Family

ID=12465898

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3629879A Pending JPS55129221A (en) 1979-03-29 1979-03-29 Preparation of oral preparation containing hardly soluble medicine

Country Status (1)

Country Link
JP (1) JPS55129221A (en)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5750913A (en) * 1980-09-09 1982-03-25 Bayer Ag Nifedipin-containing solid medicine and manufacture
EP0169684A2 (en) * 1984-07-27 1986-01-29 Reckitt And Colman Products Limited Pharmaceutical compositions
US4880623A (en) * 1985-10-15 1989-11-14 Eurand Italia S.P.A. Process for the preparation of solid nifedipine formulations of high bioavailability and with sustained effect, and formulations thus obtained
JPH02172918A (en) * 1988-10-28 1990-07-04 Egyt Gyogyszervegyeszeti Gyar Drug containing n-(2-pyridyl)-2- methyl-4-hydroxy-2h-1,2-benzothiazin- 3-carbooxamide-1,1-dioxide and preparation thereof
WO2004110448A1 (en) * 2003-06-17 2004-12-23 Kyowa Hakko Kogyo Co., Ltd. Medicinal composition containing benidipine hydrochloride
JP2006335767A (en) * 1999-09-17 2006-12-14 Novartis Ag Method of treating metabolic disorders, especially diabetes, or a disease or condition associated with diabetes
WO2007138997A1 (en) * 2006-05-26 2007-12-06 Toyama Chemical Co., Ltd. Oral composition comprising 3-[5-[4-(cyclopentyloxy) -2-hydroxybenzoyl]-2-[(3-hydroxy-1,2-benzisoxazol-6- yl)methoxy]phenyl]propionic acid or salt thereof
WO2009069643A1 (en) * 2007-11-27 2009-06-04 Toyama Chemical Co., Ltd. Solid dispersion comprising 3-[5-[4-(cyclopentyloxy)- 2-hydroxybenzoyl]-2-[(3-hydroxy-1,2-benzisoxazol-6- yl)methoxy]phenyl]propionic acid or salt thereof, or composition comprising the solid dispersion
JP2011136922A (en) * 2009-12-28 2011-07-14 Lion Corp Ibuprofen-containing pharmaceutical preparation

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2822882A1 (en) * 1977-06-07 1978-12-21 Yamanouchi Pharma Co Ltd SOLID PREPARATION COMPOSITION CONTAINING NIFEDIPINE, METHOD FOR PRODUCING AND USING IT
JPS542316A (en) * 1977-06-07 1979-01-09 Yamanouchi Pharmaceut Co Ltd Solid pharmaceutical composition containing nifedipene

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2822882A1 (en) * 1977-06-07 1978-12-21 Yamanouchi Pharma Co Ltd SOLID PREPARATION COMPOSITION CONTAINING NIFEDIPINE, METHOD FOR PRODUCING AND USING IT
JPS542316A (en) * 1977-06-07 1979-01-09 Yamanouchi Pharmaceut Co Ltd Solid pharmaceutical composition containing nifedipene

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5914446B2 (en) * 1980-09-09 1984-04-04 バイエル・アクチエンゲゼルシヤフト Solid preparation containing nifedipine and its manufacturing method
JPS5750913A (en) * 1980-09-09 1982-03-25 Bayer Ag Nifedipin-containing solid medicine and manufacture
EP0169684A2 (en) * 1984-07-27 1986-01-29 Reckitt And Colman Products Limited Pharmaceutical compositions
EP0169684A3 (en) * 1984-07-27 1989-01-18 Reckitt And Colman Products Limited Pharmaceutical compositions
US4880623A (en) * 1985-10-15 1989-11-14 Eurand Italia S.P.A. Process for the preparation of solid nifedipine formulations of high bioavailability and with sustained effect, and formulations thus obtained
JPH02172918A (en) * 1988-10-28 1990-07-04 Egyt Gyogyszervegyeszeti Gyar Drug containing n-(2-pyridyl)-2- methyl-4-hydroxy-2h-1,2-benzothiazin- 3-carbooxamide-1,1-dioxide and preparation thereof
JP2006335767A (en) * 1999-09-17 2006-12-14 Novartis Ag Method of treating metabolic disorders, especially diabetes, or a disease or condition associated with diabetes
WO2004110448A1 (en) * 2003-06-17 2004-12-23 Kyowa Hakko Kogyo Co., Ltd. Medicinal composition containing benidipine hydrochloride
WO2007138997A1 (en) * 2006-05-26 2007-12-06 Toyama Chemical Co., Ltd. Oral composition comprising 3-[5-[4-(cyclopentyloxy) -2-hydroxybenzoyl]-2-[(3-hydroxy-1,2-benzisoxazol-6- yl)methoxy]phenyl]propionic acid or salt thereof
US8093289B2 (en) 2006-05-26 2012-01-10 Toyama Chemical Co., Ltd. Oral composition comprising 3-[5-[4-(cyclopentyloxy)-2-hydroxybenzoyl]-2-[(3-hydroxy-1,2-benzisoxazol-6-yl)methoxy]phenyl]propionic acid or salt thereof
AU2007268772B2 (en) * 2006-05-26 2012-03-15 Toyama Chemical Co., Ltd. Oral composition comprising 3-[5-[4-(cyclopentyloxy) -2-hydroxybenzoyl]-2-[(3-hydroxy-1,2-benzisoxazol-6- yl)methoxy]phenyl]propionic acid or salt thereof
JP5161077B2 (en) * 2006-05-26 2013-03-13 富山化学工業株式会社 Contains 3- {5- [4- (cyclopentyloxy) -2-hydroxybenzoyl] -2-[(3-hydroxy-1,2-benzisoxazol-6-yl) methoxy] phenyl} propionic acid or a salt thereof Oral composition
WO2009069643A1 (en) * 2007-11-27 2009-06-04 Toyama Chemical Co., Ltd. Solid dispersion comprising 3-[5-[4-(cyclopentyloxy)- 2-hydroxybenzoyl]-2-[(3-hydroxy-1,2-benzisoxazol-6- yl)methoxy]phenyl]propionic acid or salt thereof, or composition comprising the solid dispersion
JP5615554B2 (en) * 2007-11-27 2014-10-29 富山化学工業株式会社 Contains 3- {5- [4- (cyclopentyloxy) -2-hydroxybenzoyl] -2-[(3-hydroxy-1,2-benzisoxazol-6-yl) methoxy] phenyl} propionic acid or a salt thereof Composition of solid dispersion
JP2011136922A (en) * 2009-12-28 2011-07-14 Lion Corp Ibuprofen-containing pharmaceutical preparation

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