GB1308533A - Benzothiazine dioxides as anti-thombotic agents - Google Patents

Benzothiazine dioxides as anti-thombotic agents

Info

Publication number
GB1308533A
GB1308533A GB2608570A GB2608570A GB1308533A GB 1308533 A GB1308533 A GB 1308533A GB 2608570 A GB2608570 A GB 2608570A GB 2608570 A GB2608570 A GB 2608570A GB 1308533 A GB1308533 A GB 1308533A
Authority
GB
United Kingdom
Prior art keywords
alkyl
phenyl
alkoxy
nitro
alkenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2608570A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of GB1308533A publication Critical patent/GB1308533A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1308533 Antithrombitic medicines PFIZER INC 29 May 1970 [2 June 1969] 26085/70 Heading A5B Compositions for the treatment of thrombosis comprise a carrier and a compound (or a salt thereof) of the formulae: wherein X and Y are H, F, Cl, Br, NO, or C 1-5 alkyl or alkoxy; R is -OR 1 , or -NHR 2 where R 1 is C 1-12 alkyl, phenyl-C 1-3 alkyl and R 2 is H, C 1-8 alkyl, C 2-6 alkenyl, cycloalkyl of up to 8 C atoms, phenyl, phenylalkyl, halogen-, hydroxy-, alkoxy-, thioalkoxy-, alkyl-, trifluoromethyl-, acetyl-, methyl sulphinyl-, methylsulphonyl- or nitro-substituted phenyl, naphthyl, pyridyl or one of a number of specified mono- and di-cyclic nitrogen-containing heterocyclic radicals which may be substituted by halogen, alkyl, alkoxy, nitro or phenyl, R 3 is H, C 1-5 alkyl, C 2-4 alkenyl or phenyl-C 1-3 alkyl, and Z is 0 or S except when R is -OR, when it is oxygen. Tablets and capsules are exemplified and other conventional oral and parenteral forms are referred to.
GB2608570A 1969-06-02 1970-05-29 Benzothiazine dioxides as anti-thombotic agents Expired GB1308533A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82971369A 1969-06-02 1969-06-02

Publications (1)

Publication Number Publication Date
GB1308533A true GB1308533A (en) 1973-02-21

Family

ID=25255342

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2608570A Expired GB1308533A (en) 1969-06-02 1970-05-29 Benzothiazine dioxides as anti-thombotic agents

Country Status (4)

Country Link
BE (1) BE751300A (en)
FR (1) FR2052924B1 (en)
GB (1) GB1308533A (en)
PH (1) PH11031A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4180662A (en) 1977-09-06 1979-12-25 Hoffmann-La Roche Inc. Thiazine derivatives
US4187303A (en) 1977-08-22 1980-02-05 Hoffmann-La Roche Inc. Thiazine derivatives
GB2224207A (en) * 1988-10-28 1990-05-02 Egyt Gyogyszervegyeszeti Gyar Pharmaceutical compositions containing piroxicam

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2539112C2 (en) * 1975-09-03 1983-12-15 Dr. Karl Thomae Gmbh, 7950 Biberach 4-Hydroxy-2H-naphtho [2,1-e] -1,2-thiazine-3-carboxamide-1,1-dioxides, processes for their preparation and pharmaceuticals containing them
GB2078738B (en) * 1980-06-27 1983-11-30 Mitsui Toatsu Chemicals Benzothiazine derivatives
US4761424A (en) * 1985-10-01 1988-08-02 Warner-Lambert Company Enolamides, pharmaceutical compositions and methods for treating inflammation

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4187303A (en) 1977-08-22 1980-02-05 Hoffmann-La Roche Inc. Thiazine derivatives
US4180662A (en) 1977-09-06 1979-12-25 Hoffmann-La Roche Inc. Thiazine derivatives
GB2224207A (en) * 1988-10-28 1990-05-02 Egyt Gyogyszervegyeszeti Gyar Pharmaceutical compositions containing piroxicam
GB2224207B (en) * 1988-10-28 1992-06-10 Egyt Gyogyszervegyeszeti Gyar Pharmaceutical composition comprising piroxicam and lactose for use in making tablets or capsules

Also Published As

Publication number Publication date
PH11031A (en) 1977-10-25
FR2052924B1 (en) 1974-08-09
BE751300A (en) 1970-12-02
FR2052924A1 (en) 1971-04-16

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Legal Events

Date Code Title Description
PS Patent sealed
PE20 Patent expired after termination of 20 years