GB2203149B - New ribofuranuronic acid derivatives - Google Patents

New ribofuranuronic acid derivatives

Info

Publication number
GB2203149B
GB2203149B GB8807750A GB8807750A GB2203149B GB 2203149 B GB2203149 B GB 2203149B GB 8807750 A GB8807750 A GB 8807750A GB 8807750 A GB8807750 A GB 8807750A GB 2203149 B GB2203149 B GB 2203149B
Authority
GB
United Kingdom
Prior art keywords
new
acid derivatives
ribofuranuronic acid
ribofuranuronic
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
GB8807750A
Other languages
English (en)
Other versions
GB8807750D0 (en
GB2203149A (en
Inventor
Fulvio Gadient
Arnold Vogel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of GB8807750D0 publication Critical patent/GB8807750D0/en
Publication of GB2203149A publication Critical patent/GB2203149A/en
Application granted granted Critical
Publication of GB2203149B publication Critical patent/GB2203149B/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GB8807750A 1987-04-06 1988-03-31 New ribofuranuronic acid derivatives Expired - Lifetime GB2203149B (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE3711562 1987-04-06
DE3711563 1987-04-06
DE3711561 1987-04-06
DE3711564 1987-04-06

Publications (3)

Publication Number Publication Date
GB8807750D0 GB8807750D0 (en) 1988-05-05
GB2203149A GB2203149A (en) 1988-10-12
GB2203149B true GB2203149B (en) 1991-02-13

Family

ID=27433888

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8807750A Expired - Lifetime GB2203149B (en) 1987-04-06 1988-03-31 New ribofuranuronic acid derivatives

Country Status (22)

Country Link
JP (1) JPS63258892A (enrdf_load_html_response)
KR (1) KR880012629A (enrdf_load_html_response)
AT (1) AT393507B (enrdf_load_html_response)
AU (1) AU609109B2 (enrdf_load_html_response)
BE (1) BE1002151A5 (enrdf_load_html_response)
CA (1) CA1326017C (enrdf_load_html_response)
CH (1) CH676121A5 (enrdf_load_html_response)
DK (1) DK183488A (enrdf_load_html_response)
ES (1) ES2007177A6 (enrdf_load_html_response)
FI (1) FI87463C (enrdf_load_html_response)
FR (1) FR2613367A1 (enrdf_load_html_response)
GB (1) GB2203149B (enrdf_load_html_response)
HU (1) HU201955B (enrdf_load_html_response)
IL (1) IL85969A (enrdf_load_html_response)
IT (1) IT1219892B (enrdf_load_html_response)
LU (1) LU87181A1 (enrdf_load_html_response)
MY (1) MY102323A (enrdf_load_html_response)
NL (1) NL8800862A (enrdf_load_html_response)
NZ (1) NZ224131A (enrdf_load_html_response)
PH (1) PH25424A (enrdf_load_html_response)
PT (1) PT87153B (enrdf_load_html_response)
SE (1) SE8801236A0 (enrdf_load_html_response)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4755594A (en) * 1986-01-31 1988-07-05 Warner-Lambert Company N6 -substituted adenosines
US5063233A (en) * 1986-11-14 1991-11-05 Ciba-Geigy Corporation N9 -cyclopentyl-substituted adenine derivatives useful as adenosine receptor agonists
US4954504A (en) * 1986-11-14 1990-09-04 Ciba-Geigy Corporation N9 -cyclopentyl-substituted adenine derivatives having adenosine-2 receptor stimulating activity
NL8702926A (nl) * 1986-12-15 1988-07-01 Sandoz Ag Nieuwe furanuronzuurderivaten en werkwijzen voor het bereiden en toepassen van deze derivaten.
US4968697A (en) * 1987-02-04 1990-11-06 Ciba-Geigy Corporation 2-substituted adenosine 5'-carboxamides as antihypertensive agents
EP0277917A3 (en) * 1987-02-04 1990-03-28 Ciba-Geigy Ag Certain adenosine 5'-carboxamide derivatives
US5140015A (en) * 1990-02-20 1992-08-18 Whitby Research, Inc. 2-aralkoxy and 2-alkoxy adenosine derivatives as coronary vasodilators and antihypertensive agents
USRE36494E (en) * 1990-02-20 2000-01-11 Discovery Therapeutics, Inc. 2-aralkoxy and 2-alkoxy adenosine derivatives as coronary vasodilators and antihypertensive agents
IT1254915B (it) * 1992-04-24 1995-10-11 Gloria Cristalli Derivati di adenosina ad attivita' a2 agonista
GB9301000D0 (en) * 1993-01-20 1993-03-10 Glaxo Group Ltd Chemical compounds
TW528755B (en) 1996-12-24 2003-04-21 Glaxo Group Ltd 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
YU44900A (sh) 1998-01-31 2003-01-31 Glaxo Group Limited Derivati 2-(purin-9-il)tetrahidrofuran-3,4-diola
KR20010071591A (ko) 1998-06-23 2001-07-28 그레이엄 브레레톤, 레슬리 에드워즈 2-(퓨린-9-일)-테트라히드로푸란-3,4-디올 유도체
AR023463A1 (es) 1999-04-16 2002-09-04 Schering Corp Uso de compuestos de azetidinona
US20050033044A1 (en) 2003-05-19 2005-02-10 Bristol-Myers Squibb Pharma Company Methods for preparing 2-alkynyladenosine derivatives
AR049384A1 (es) 2004-05-24 2006-07-26 Glaxo Group Ltd Derivados de purina
JP5011112B2 (ja) * 2004-09-20 2012-08-29 イノテック ファーマシューティカルズ コーポレイション プリン誘導体を含有する炎症性疾患の治療用医薬
GB0514809D0 (en) 2005-07-19 2005-08-24 Glaxo Group Ltd Compounds

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4167565A (en) * 1976-11-08 1979-09-11 Abbott Laboratories Adenosine-5'-carboxamides and method of use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH606084A5 (en) * 1975-02-18 1978-10-13 Hoffmann La Roche (Di) nitrates of adenosine -5'-carboxylic acid derivs
DE3406533A1 (de) * 1984-02-23 1985-08-29 Boehringer Mannheim Gmbh, 6800 Mannheim Verwendung von adenosin-derivaten als antiallergica und arzneimittel, die diese enthalten
NL8702926A (nl) * 1986-12-15 1988-07-01 Sandoz Ag Nieuwe furanuronzuurderivaten en werkwijzen voor het bereiden en toepassen van deze derivaten.
EP0277917A3 (en) * 1987-02-04 1990-03-28 Ciba-Geigy Ag Certain adenosine 5'-carboxamide derivatives

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4167565A (en) * 1976-11-08 1979-09-11 Abbott Laboratories Adenosine-5'-carboxamides and method of use

Also Published As

Publication number Publication date
PT87153B (pt) 1992-07-31
GB8807750D0 (en) 1988-05-05
ES2007177A6 (es) 1989-06-01
SE8801236L (sv) 1988-10-17
LU87181A1 (fr) 1988-11-17
CH676121A5 (enrdf_load_html_response) 1990-12-14
FR2613367A1 (fr) 1988-10-07
KR880012629A (ko) 1988-11-28
ATA87388A (de) 1991-04-15
DK183488A (da) 1988-10-07
MY102323A (en) 1992-05-28
FI87463B (fi) 1992-09-30
NL8800862A (nl) 1988-11-01
DK183488D0 (da) 1988-04-05
IL85969A (en) 1992-03-29
AU1415188A (en) 1988-10-06
FI881571L (fi) 1988-10-07
CA1326017C (en) 1994-01-11
SE8801236A0 (sv) 1988-10-17
JPS63258892A (ja) 1988-10-26
IT1219892B (it) 1990-05-24
IL85969A0 (en) 1988-09-30
AU609109B2 (en) 1991-04-26
AT393507B (de) 1991-11-11
FI881571A0 (fi) 1988-04-05
GB2203149A (en) 1988-10-12
BE1002151A5 (fr) 1990-08-07
NZ224131A (en) 1991-12-23
FI87463C (fi) 1993-01-11
HUT48902A (en) 1989-07-28
IT8847794A0 (it) 1988-03-30
SE8801236D0 (sv) 1988-04-05
PT87153A (pt) 1988-05-01
HU201955B (en) 1991-01-28
PH25424A (enrdf_load_html_response) 1991-07-01

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19950331