GB2161076B - Analgesic and anti-inflammatory compositions comprising xanthines and methods of using same - Google Patents

Analgesic and anti-inflammatory compositions comprising xanthines and methods of using same

Info

Publication number
GB2161076B
GB2161076B GB08519256A GB8519256A GB2161076B GB 2161076 B GB2161076 B GB 2161076B GB 08519256 A GB08519256 A GB 08519256A GB 8519256 A GB8519256 A GB 8519256A GB 2161076 B GB2161076 B GB 2161076B
Authority
GB
United Kingdom
Prior art keywords
xanthines
analgesic
methods
same
inflammatory compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08519256A
Other languages
English (en)
Other versions
GB8519256D0 (en
GB2161076A (en
Inventor
Abraham Sunshine
Eugene M Laska
Carole E Siegel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richardson Vicks Inc
Original Assignee
Richardson Vicks Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richardson Vicks Inc filed Critical Richardson Vicks Inc
Publication of GB8519256D0 publication Critical patent/GB8519256D0/en
Publication of GB2161076A publication Critical patent/GB2161076A/en
Application granted granted Critical
Publication of GB2161076B publication Critical patent/GB2161076B/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GB08519256A 1983-12-12 1984-12-12 Analgesic and anti-inflammatory compositions comprising xanthines and methods of using same Expired GB2161076B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/560,576 US4558051A (en) 1983-10-11 1983-12-12 Analgesic and anti-inflammatory compositions comprising xanthines and methods of using same
PCT/US1984/002035 WO1985002540A1 (en) 1983-12-12 1984-12-12 Analgesic and anti-inflammatory compositions comprising xanthines and methods of using same

Publications (3)

Publication Number Publication Date
GB8519256D0 GB8519256D0 (en) 1985-09-04
GB2161076A GB2161076A (en) 1986-01-08
GB2161076B true GB2161076B (en) 1988-03-30

Family

ID=24238396

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08519256A Expired GB2161076B (en) 1983-12-12 1984-12-12 Analgesic and anti-inflammatory compositions comprising xanthines and methods of using same

Country Status (15)

Country Link
US (1) US4558051A (cg-RX-API-DMAC10.html)
EP (1) EP0165308B1 (cg-RX-API-DMAC10.html)
JP (1) JPS61500665A (cg-RX-API-DMAC10.html)
AT (1) AT389997B (cg-RX-API-DMAC10.html)
AU (1) AU574419B2 (cg-RX-API-DMAC10.html)
CA (1) CA1246453A (cg-RX-API-DMAC10.html)
CH (1) CH669730A5 (cg-RX-API-DMAC10.html)
DE (1) DE3490583T1 (cg-RX-API-DMAC10.html)
GB (1) GB2161076B (cg-RX-API-DMAC10.html)
IE (1) IE58158B1 (cg-RX-API-DMAC10.html)
IT (1) IT1177389B (cg-RX-API-DMAC10.html)
NL (1) NL8420316A (cg-RX-API-DMAC10.html)
SE (1) SE469874B (cg-RX-API-DMAC10.html)
WO (1) WO1985002540A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA849675B (cg-RX-API-DMAC10.html)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3508097A1 (de) * 1984-07-21 1986-02-06 Hoechst Ag, 6230 Frankfurt Kombinationspraeparat aus xanthinderivaten und o-acetylsalicylsaeure bzw. deren pharmakologisch vertraeglichen salzen und dessen verwendung
HU197746B (en) * 1985-09-05 1989-05-29 Sandoz Ag Process for producing xantin derivatives and pharmaceutical compositions containing them
CH669523A5 (cg-RX-API-DMAC10.html) * 1986-06-25 1989-03-31 Mepha Ag
EP0258191B1 (en) * 1986-08-28 1992-05-27 Sandoz Ag Xanthine derivatives
CH670090A5 (cg-RX-API-DMAC10.html) * 1986-10-27 1989-05-12 Nestle Sa
GB8626098D0 (en) * 1986-10-31 1986-12-03 Euro Celtique Sa Controlled release hydromorphone composition
GB8629567D0 (en) * 1986-12-10 1987-01-21 Boots Co Plc Therapeutic agents
US5272153A (en) * 1986-12-31 1993-12-21 Hoechst-Roussel Pharmaceuticals, Inc. Method of inhibiting the activity of leukocyte derived cytokines
US5196430A (en) * 1986-12-31 1993-03-23 Hoechst-Roussel Pharmaceuticals Inc. Method of inhibiting the activity of leukocyte derived cytokines
US5196429A (en) * 1986-12-31 1993-03-23 Hoechst-Roussel Pharmaceuticals Inc. Method of inhibiting the activity of leukocyte derived cytokines
US4859704A (en) * 1987-10-15 1989-08-22 Oratech Pharmaceutical Development Corporation Water soluble ibuprofen compositions and methods of making them
US4861797A (en) * 1987-10-15 1989-08-29 Oratech Pharmaceutical Development Corporation Liquid ibuprofen compositions and methods of making them
JPH0228141A (ja) * 1987-11-13 1990-01-30 Glaxo Group Ltd フェネタノールアミン誘導体
US4883818A (en) * 1987-11-17 1989-11-28 Analgesic Associates Onset-hastened/enhanced analgesia
IE882585L (en) * 1988-08-25 1990-02-25 Prendergast Patrick T Viral treatment system
JP2843634B2 (ja) * 1989-03-06 1999-01-06 協和醗酵工業株式会社 キサンチン誘導体
GB8906792D0 (en) * 1989-03-23 1989-05-10 Beecham Wuelfing Gmbh & Co Kg Treatment and compounds
AU662297B2 (en) * 1990-09-11 1995-08-31 Richardson-Vicks Inc. Method for providing improved analgesic effect
JPH08501796A (ja) * 1992-09-29 1996-02-27 メルク エンド カンパニー インコーポレーテッド イブプロフェン−カフェイン配合物
US5340813A (en) * 1992-11-09 1994-08-23 Cell Therapeutics, Inc. Substituted aminoalkyl xanthine compounds
US5817662A (en) * 1992-11-09 1998-10-06 Cell Therapeutics, Inc. Substituted amino alkyl compounds
WO1994025462A1 (en) * 1993-05-03 1994-11-10 The United States Of America, Represented By The 8-substituted 1,3,7-trialkyl-xanthine derivatives as a2-selective adenosine receptor antagonists
US5451409A (en) * 1993-11-22 1995-09-19 Rencher; William F. Sustained release matrix system using hydroxyethyl cellulose and hydroxypropyl cellulose polymer blends
US6103730A (en) * 1994-03-24 2000-08-15 Cell Therapeutics, Inc. Amine substituted compounds
US5801182A (en) * 1994-03-24 1998-09-01 Cell Therapeutics, Inc. Amine substituted compounds
US5807861A (en) * 1994-03-24 1998-09-15 Cell Therapeutics, Inc. Amine substituted xanthinyl compounds
US6348216B1 (en) * 1996-06-10 2002-02-19 Knoll Pharmaceutical Company Ibuprofen and narcotic analgesic compositions
US6361794B1 (en) 1996-06-12 2002-03-26 Basf Corporation Method of making ibuprofen and narcotic analgesic composition
US20090149479A1 (en) * 1998-11-02 2009-06-11 Elan Pharma International Limited Dosing regimen
US6211246B1 (en) * 1999-06-10 2001-04-03 Mcneil-Ppc, Inc. Rapidly absorbed liquid compositions
US6586429B2 (en) * 2000-11-29 2003-07-01 Cell Therapeutics, Inc. Tricyclic fused xanthine compounds and their uses
US8329216B2 (en) 2001-07-06 2012-12-11 Endo Pharmaceuticals Inc. Oxymorphone controlled release formulations
ATE376832T1 (de) 2001-07-06 2007-11-15 Penwest Pharmaceuticals Co Verzögert freisetzende formulierungen von oxymorphon
CA2452871C (en) 2001-07-06 2011-10-04 Endo Pharmaceuticals, Inc. Oxymorphone controlled release formulations
US7317017B2 (en) * 2002-11-08 2008-01-08 Cv Therapeutics, Inc. A2B adenosine receptor antagonists
US20080318983A1 (en) * 2001-11-09 2008-12-25 Rao Kalla A2b adenosine receptor antagonists
US6977300B2 (en) * 2001-11-09 2005-12-20 Cv Therapeutics, Inc. A2B adenosine receptor antagonists
MXPA04004388A (es) 2001-11-09 2005-05-16 Cv Therapeutics Inc Antagonistas del receptor a2b de adenosina.
US7125993B2 (en) * 2001-11-09 2006-10-24 Cv Therapeutics, Inc. A2B adenosine receptor antagonists
US20050137262A1 (en) * 2003-12-22 2005-06-23 Hu Patrick C. Highly concentrated pourable aqueous solutions of potassium ibuprofen, their preparation and their uses
US20060058322A1 (en) * 2004-09-01 2006-03-16 Dewan Zeng Method of wound healing using A2B adenosine receptor antagonists
CL2007002425A1 (es) * 2006-08-22 2008-06-27 Albermarle Corp Procedimiento de preparacion controlado de sal sodica de ibuprofeno de tamano de particula mediano; y dichas particulas de sal sodica.
CN107530349B (zh) 2015-04-08 2021-01-08 路易斯和克拉克制药公司 作为a2b拮抗剂的黄嘌呤取代的炔基氨基甲酸酯/反式氨基甲酸酯
CN109912598B (zh) * 2019-03-27 2022-09-13 四川大学华西医院 防治炎症反应的核苷类衍生物及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3439094A (en) * 1967-07-20 1969-04-15 Warner Lambert Pharmaceutical Analgesic compositions containing namol xenyrate,caffeine and acetyl-rho-aminophenol
US3936528A (en) * 1974-02-13 1976-02-03 Syntex Corporation Analgesic formulations having enhanced therapeutic activity
AU532600B2 (en) * 1977-04-02 1983-10-06 Hoechst A.G. Alkenyl xanthines and pharmaceutical compositions
JPS56154416A (en) * 1980-04-30 1981-11-30 Kaken Pharmaceut Co Ltd Antipyretic analgesic composition
US4420483A (en) * 1982-07-22 1983-12-13 Richardson-Vicks, Inc. Analgesic and anti-inflammatory compositions comprising ibuprofen and methods of using same
CH659391A5 (de) * 1982-07-22 1987-01-30 Richardson Vicks Inc Koffein enthaltende, analgetische und antiinflammatorische pharmazeutische zubereitung.
US4479956A (en) * 1983-04-26 1984-10-30 Analgeic Associates Analgesic compositions comprising propiram and methods of using same

Also Published As

Publication number Publication date
WO1985002540A1 (en) 1985-06-20
GB8519256D0 (en) 1985-09-04
EP0165308A1 (en) 1985-12-27
NL8420316A (nl) 1985-11-01
SE469874B (sv) 1993-10-04
IT1177389B (it) 1987-08-26
IE58158B1 (en) 1993-07-28
SE8503762D0 (sv) 1985-08-09
CA1246453A (en) 1988-12-13
DE3490583T1 (de) 1986-04-03
EP0165308B1 (en) 1989-03-22
EP0165308A4 (en) 1986-05-16
ZA849675B (en) 1985-07-31
AT389997B (de) 1990-02-26
IE843166L (en) 1985-06-12
US4558051A (en) 1985-12-10
GB2161076A (en) 1986-01-08
IT8424009A0 (it) 1984-12-12
IT8424009A1 (it) 1986-06-12
AU3747485A (en) 1985-06-26
ATA905384A (de) 1989-08-15
CH669730A5 (cg-RX-API-DMAC10.html) 1989-04-14
JPS61500665A (ja) 1986-04-10
SE8503762L (sv) 1985-08-09
AU574419B2 (en) 1988-07-07

Similar Documents

Publication Publication Date Title
GB2161076B (en) Analgesic and anti-inflammatory compositions comprising xanthines and methods of using same
ZA849680B (en) Analgesic and anti-inflammatory compositions comprising xanthine and methods of using same
GB2162747B (en) Analgesic and anti-inflammatory compositions comprising diphenhydramine and methods of using same
PH23495A (en) Phenoxyalkylaminopyrimidine derivatives and the composition and method of use thereof
ZW20383A1 (en) Compounds compositions and methods of use therefor
NZ210633A (en) Glycerol derivatives and pharmaceutical compositions thereof
GB2182323B (en) Settable compositions and methods of use thereof
ZA835324B (en) Analgesic and anti-inflammatory compositions comprising caffeine and methods of using same
GB2132891B (en) Improved analgesic and anti-inflammatory compositions comprising ibuprofen and method of using same
AU8258282A (en) Analgesic compositions and methods of use
ZW7488A1 (en) New method and compositions of matter
PH17898A (en) Analgesic mixture of nalsuphine and isuprofen
PH19352A (en) Fluoromethylthiooxacephalosporins derivatives compositions containing same and method of use thereof
PT79858B (en) Process for the preparation of azolyl-aryl-alcanol and pharmaceutical compositions therewith
AU576717B2 (en) N6 - bicycloadenosines and methods of use
DE3462792D1 (en) Enhanced 2-hydroxy-4-methylthiobutanoic acid composition and method of preparation
GB2160893B (en) Soldering compositions and methods of use
PH17091A (en) Cycloheptene derivatives and method of use
DE3261724D1 (en) Analgesic and anti-inflammatory composition
GB8323796D0 (en) Preparation of haloacetals and halodioxolanes
PH17913A (en) Analgesic mixture of nalbuphine and flurbiprofen
PT79990A (en) Process for the preparation of diazepine-indoles and of pharmaceutical compositions therewith
PH17118A (en) Antihypertensive pharmaceutical compositions and its method of use
PH21826A (en) N-aryl-n(-piperidinyl)-alkoxyalkylamides and pharmaceutical compositions and methods of use employing such compounds
DE3276871D1 (en) Preparation of 6-deoxy-d-fructose and 6-deoxy-l-sorbose

Legal Events

Date Code Title Description
PE20 Patent expired after termination of 20 years

Effective date: 20041211