IT8424009A1 - Composizioni analgesiche ed anti-infiammatorie migliorate, comprendenti xantine e metodi di utilizzare le stesse - Google Patents
Composizioni analgesiche ed anti-infiammatorie migliorate, comprendenti xantine e metodi di utilizzare le stesseInfo
- Publication number
- IT8424009A1 IT8424009A1 IT1984A24009A IT2400984A IT8424009A1 IT 8424009 A1 IT8424009 A1 IT 8424009A1 IT 1984A24009 A IT1984A24009 A IT 1984A24009A IT 2400984 A IT2400984 A IT 2400984A IT 8424009 A1 IT8424009 A1 IT 8424009A1
- Authority
- IT
- Italy
- Prior art keywords
- xanthines
- methods
- inflammatory compositions
- improved analgesic
- analgesic
- Prior art date
Links
- LRFVTYWOQMYALW-UHFFFAOYSA-N 9H-xanthine Chemical class O=C1NC(=O)NC2=C1NC=N2 LRFVTYWOQMYALW-UHFFFAOYSA-N 0.000 title 1
- 230000000202 analgesic effect Effects 0.000 title 1
- 230000003110 anti-inflammatory effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 229940065721 systemic for obstructive airway disease xanthines Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/560,576 US4558051A (en) | 1983-10-11 | 1983-12-12 | Analgesic and anti-inflammatory compositions comprising xanthines and methods of using same |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| IT8424009A0 IT8424009A0 (it) | 1984-12-12 |
| IT8424009A1 true IT8424009A1 (it) | 1986-06-12 |
| IT1177389B IT1177389B (it) | 1987-08-26 |
Family
ID=24238396
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT24009/84A IT1177389B (it) | 1983-12-12 | 1984-12-12 | Composizioni analgesiche ed anti-infiammatorie migliorate, comprendente xantine e metodi di utilizzare le stesse |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4558051A (it) |
| EP (1) | EP0165308B1 (it) |
| JP (1) | JPS61500665A (it) |
| AT (1) | AT389997B (it) |
| AU (1) | AU574419B2 (it) |
| CA (1) | CA1246453A (it) |
| CH (1) | CH669730A5 (it) |
| DE (1) | DE3490583T1 (it) |
| GB (1) | GB2161076B (it) |
| IE (1) | IE58158B1 (it) |
| IT (1) | IT1177389B (it) |
| NL (1) | NL8420316A (it) |
| SE (1) | SE469874B (it) |
| WO (1) | WO1985002540A1 (it) |
| ZA (1) | ZA849675B (it) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3508097A1 (de) * | 1984-07-21 | 1986-02-06 | Hoechst Ag, 6230 Frankfurt | Kombinationspraeparat aus xanthinderivaten und o-acetylsalicylsaeure bzw. deren pharmakologisch vertraeglichen salzen und dessen verwendung |
| HU197746B (en) * | 1985-09-05 | 1989-05-29 | Sandoz Ag | Process for producing xantin derivatives and pharmaceutical compositions containing them |
| CH669523A5 (it) * | 1986-06-25 | 1989-03-31 | Mepha Ag | |
| ES2033922T3 (es) * | 1986-08-28 | 1993-04-01 | Sandoz Ag | Procedimiento para preparar nuevos derivados de xantina. |
| CH670090A5 (it) * | 1986-10-27 | 1989-05-12 | Nestle Sa | |
| GB8626098D0 (en) * | 1986-10-31 | 1986-12-03 | Euro Celtique Sa | Controlled release hydromorphone composition |
| GB8629567D0 (en) * | 1986-12-10 | 1987-01-21 | Boots Co Plc | Therapeutic agents |
| US5196430A (en) * | 1986-12-31 | 1993-03-23 | Hoechst-Roussel Pharmaceuticals Inc. | Method of inhibiting the activity of leukocyte derived cytokines |
| US5196429A (en) * | 1986-12-31 | 1993-03-23 | Hoechst-Roussel Pharmaceuticals Inc. | Method of inhibiting the activity of leukocyte derived cytokines |
| US5272153A (en) * | 1986-12-31 | 1993-12-21 | Hoechst-Roussel Pharmaceuticals, Inc. | Method of inhibiting the activity of leukocyte derived cytokines |
| US4861797A (en) * | 1987-10-15 | 1989-08-29 | Oratech Pharmaceutical Development Corporation | Liquid ibuprofen compositions and methods of making them |
| US4859704A (en) * | 1987-10-15 | 1989-08-22 | Oratech Pharmaceutical Development Corporation | Water soluble ibuprofen compositions and methods of making them |
| IE883400L (en) * | 1987-11-13 | 1989-05-13 | Fuisz Technologies Ltd | Phenethanolamine derivatives |
| US4883818A (en) * | 1987-11-17 | 1989-11-28 | Analgesic Associates | Onset-hastened/enhanced analgesia |
| IE882585L (en) * | 1988-08-25 | 1990-02-25 | Prendergast Patrick T | Viral treatment system |
| JP2843634B2 (ja) * | 1989-03-06 | 1999-01-06 | 協和醗酵工業株式会社 | キサンチン誘導体 |
| GB8906792D0 (en) * | 1989-03-23 | 1989-05-10 | Beecham Wuelfing Gmbh & Co Kg | Treatment and compounds |
| AU662297B2 (en) * | 1990-09-11 | 1995-08-31 | Richardson-Vicks Inc. | Method for providing improved analgesic effect |
| CA2144152A1 (en) * | 1992-09-29 | 1994-04-14 | Robert T. Sims | Ibuprofen-caffine combinations |
| US5817662A (en) * | 1992-11-09 | 1998-10-06 | Cell Therapeutics, Inc. | Substituted amino alkyl compounds |
| US5340813A (en) * | 1992-11-09 | 1994-08-23 | Cell Therapeutics, Inc. | Substituted aminoalkyl xanthine compounds |
| WO1994025462A1 (en) * | 1993-05-03 | 1994-11-10 | The United States Of America, Represented By The | 8-substituted 1,3,7-trialkyl-xanthine derivatives as a2-selective adenosine receptor antagonists |
| US5451409A (en) * | 1993-11-22 | 1995-09-19 | Rencher; William F. | Sustained release matrix system using hydroxyethyl cellulose and hydroxypropyl cellulose polymer blends |
| US6103730A (en) * | 1994-03-24 | 2000-08-15 | Cell Therapeutics, Inc. | Amine substituted compounds |
| US5807861A (en) * | 1994-03-24 | 1998-09-15 | Cell Therapeutics, Inc. | Amine substituted xanthinyl compounds |
| US5801182A (en) * | 1994-03-24 | 1998-09-01 | Cell Therapeutics, Inc. | Amine substituted compounds |
| US6348216B1 (en) * | 1996-06-10 | 2002-02-19 | Knoll Pharmaceutical Company | Ibuprofen and narcotic analgesic compositions |
| US6361794B1 (en) | 1996-06-12 | 2002-03-26 | Basf Corporation | Method of making ibuprofen and narcotic analgesic composition |
| US20090149479A1 (en) * | 1998-11-02 | 2009-06-11 | Elan Pharma International Limited | Dosing regimen |
| US6211246B1 (en) * | 1999-06-10 | 2001-04-03 | Mcneil-Ppc, Inc. | Rapidly absorbed liquid compositions |
| US6586429B2 (en) * | 2000-11-29 | 2003-07-01 | Cell Therapeutics, Inc. | Tricyclic fused xanthine compounds and their uses |
| US8329216B2 (en) | 2001-07-06 | 2012-12-11 | Endo Pharmaceuticals Inc. | Oxymorphone controlled release formulations |
| US20030129234A1 (en) | 2001-07-06 | 2003-07-10 | Penwest Pharmaceuticals Company | Methods of making sustained release formulations of oxymorphone |
| AU2002318211B2 (en) | 2001-07-06 | 2007-07-12 | Endo Pharmaceuticals, Inc. | Parenteral administration of 6-hydroxy-oxymorphone for use as an analgesic |
| US6977300B2 (en) * | 2001-11-09 | 2005-12-20 | Cv Therapeutics, Inc. | A2B adenosine receptor antagonists |
| US7317017B2 (en) * | 2002-11-08 | 2008-01-08 | Cv Therapeutics, Inc. | A2B adenosine receptor antagonists |
| US7125993B2 (en) * | 2001-11-09 | 2006-10-24 | Cv Therapeutics, Inc. | A2B adenosine receptor antagonists |
| US6825349B2 (en) | 2001-11-09 | 2004-11-30 | Cv Therapeutics Inc. | A2B adenosine receptor antagonists |
| US20080318983A1 (en) * | 2001-11-09 | 2008-12-25 | Rao Kalla | A2b adenosine receptor antagonists |
| US20050137262A1 (en) * | 2003-12-22 | 2005-06-23 | Hu Patrick C. | Highly concentrated pourable aqueous solutions of potassium ibuprofen, their preparation and their uses |
| PT1789053E (pt) * | 2004-09-01 | 2012-08-09 | Gilead Sciences Inc | Método de cicatrização de feridas utilizando antagonistas dos receptores de adenosina a2b |
| CL2007002425A1 (es) * | 2006-08-22 | 2008-06-27 | Albermarle Corp | Procedimiento de preparacion controlado de sal sodica de ibuprofeno de tamano de particula mediano; y dichas particulas de sal sodica. |
| CN107530349B (zh) | 2015-04-08 | 2021-01-08 | 路易斯和克拉克制药公司 | 作为a2b拮抗剂的黄嘌呤取代的炔基氨基甲酸酯/反式氨基甲酸酯 |
| CN109912598B (zh) * | 2019-03-27 | 2022-09-13 | 四川大学华西医院 | 防治炎症反应的核苷类衍生物及其应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3439094A (en) * | 1967-07-20 | 1969-04-15 | Warner Lambert Pharmaceutical | Analgesic compositions containing namol xenyrate,caffeine and acetyl-rho-aminophenol |
| US3936528A (en) * | 1974-02-13 | 1976-02-03 | Syntex Corporation | Analgesic formulations having enhanced therapeutic activity |
| AU532600B2 (en) * | 1977-04-02 | 1983-10-06 | Hoechst A.G. | Alkenyl xanthines and pharmaceutical compositions |
| JPS56154416A (en) * | 1980-04-30 | 1981-11-30 | Kaken Pharmaceut Co Ltd | Antipyretic analgesic composition |
| ZA835326B (en) * | 1982-07-22 | 1984-09-26 | Richardson Vicks Inc | Analgesic and anti-inflammatory compositions comprising caffeine and methods of using same |
| US4420483A (en) * | 1982-07-22 | 1983-12-13 | Richardson-Vicks, Inc. | Analgesic and anti-inflammatory compositions comprising ibuprofen and methods of using same |
| US4479956A (en) * | 1983-04-26 | 1984-10-30 | Analgeic Associates | Analgesic compositions comprising propiram and methods of using same |
-
1983
- 1983-12-12 US US06/560,576 patent/US4558051A/en not_active Expired - Lifetime
-
1984
- 1984-12-10 IE IE316684A patent/IE58158B1/en not_active IP Right Cessation
- 1984-12-11 CA CA000469837A patent/CA1246453A/en not_active Expired
- 1984-12-12 ZA ZA849675A patent/ZA849675B/xx unknown
- 1984-12-12 IT IT24009/84A patent/IT1177389B/it active
- 1984-12-12 WO PCT/US1984/002035 patent/WO1985002540A1/en active IP Right Grant
- 1984-12-12 DE DE19843490583 patent/DE3490583T1/de not_active Withdrawn
- 1984-12-12 GB GB08519256A patent/GB2161076B/en not_active Expired
- 1984-12-12 JP JP60500078A patent/JPS61500665A/ja active Pending
- 1984-12-12 AU AU37474/85A patent/AU574419B2/en not_active Expired
- 1984-12-12 NL NL8420316A patent/NL8420316A/nl unknown
- 1984-12-12 AT AT0905384A patent/AT389997B/de not_active IP Right Cessation
- 1984-12-12 EP EP85900409A patent/EP0165308B1/en not_active Expired
-
1985
- 1985-08-09 SE SE8503762A patent/SE469874B/sv not_active IP Right Cessation
- 1985-12-12 CH CH3505/85A patent/CH669730A5/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IE843166L (en) | 1985-06-12 |
| SE8503762L (sv) | 1985-08-09 |
| GB8519256D0 (en) | 1985-09-04 |
| DE3490583T1 (de) | 1986-04-03 |
| CA1246453A (en) | 1988-12-13 |
| WO1985002540A1 (en) | 1985-06-20 |
| CH669730A5 (it) | 1989-04-14 |
| ZA849675B (en) | 1985-07-31 |
| GB2161076B (en) | 1988-03-30 |
| SE469874B (sv) | 1993-10-04 |
| AU574419B2 (en) | 1988-07-07 |
| IT8424009A0 (it) | 1984-12-12 |
| AT389997B (de) | 1990-02-26 |
| EP0165308B1 (en) | 1989-03-22 |
| EP0165308A4 (en) | 1986-05-16 |
| ATA905384A (de) | 1989-08-15 |
| US4558051A (en) | 1985-12-10 |
| IT1177389B (it) | 1987-08-26 |
| EP0165308A1 (en) | 1985-12-27 |
| JPS61500665A (ja) | 1986-04-10 |
| GB2161076A (en) | 1986-01-08 |
| IE58158B1 (en) | 1993-07-28 |
| AU3747485A (en) | 1985-06-26 |
| NL8420316A (nl) | 1985-11-01 |
| SE8503762D0 (sv) | 1985-08-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19981231 |