GB2140019B - Matrix composition for transdermal drug delivery systems - Google Patents

Matrix composition for transdermal drug delivery systems

Info

Publication number
GB2140019B
GB2140019B GB08407741A GB8407741A GB2140019B GB 2140019 B GB2140019 B GB 2140019B GB 08407741 A GB08407741 A GB 08407741A GB 8407741 A GB8407741 A GB 8407741A GB 2140019 B GB2140019 B GB 2140019B
Authority
GB
United Kingdom
Prior art keywords
drug delivery
delivery systems
matrix composition
transdermal drug
transdermal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08407741A
Other languages
English (en)
Other versions
GB8407741D0 (en
GB2140019A (en
Inventor
David James Enscore
Robert Martin Gale
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of GB8407741D0 publication Critical patent/GB8407741D0/en
Publication of GB2140019A publication Critical patent/GB2140019A/en
Application granted granted Critical
Publication of GB2140019B publication Critical patent/GB2140019B/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
    • A61K35/08—Mineral waters; Sea water
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GB08407741A 1983-05-04 1984-03-26 Matrix composition for transdermal drug delivery systems Expired GB2140019B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/491,490 US4559222A (en) 1983-05-04 1983-05-04 Matrix composition for transdermal therapeutic system

Publications (3)

Publication Number Publication Date
GB8407741D0 GB8407741D0 (en) 1984-05-02
GB2140019A GB2140019A (en) 1984-11-21
GB2140019B true GB2140019B (en) 1986-09-17

Family

ID=23952451

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08407741A Expired GB2140019B (en) 1983-05-04 1984-03-26 Matrix composition for transdermal drug delivery systems

Country Status (15)

Country Link
US (1) US4559222A (enExample)
JP (1) JPS59206307A (enExample)
KR (1) KR890000650B1 (enExample)
AU (1) AU558304B2 (enExample)
BE (1) BE899444A (enExample)
CA (1) CA1217139A (enExample)
CH (1) CH666190A5 (enExample)
DE (1) DE3416248C2 (enExample)
ES (1) ES8600943A1 (enExample)
FR (1) FR2545357B1 (enExample)
GB (1) GB2140019B (enExample)
IT (1) IT1179635B (enExample)
NL (1) NL190508C (enExample)
SE (1) SE463012B (enExample)
ZA (1) ZA843037B (enExample)

Families Citing this family (132)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH666406A5 (de) * 1984-02-29 1988-07-29 Sandoz Ag Verfahren zur herstellung von mikrokapseln, welche bromokriptinmesylat als pharmakologischen wirkstoff enthalten.
EP0156080B2 (en) * 1984-03-05 1993-10-20 Nitto Denko Corporation Percutaneous absorption type adhesive pharmaceutical preparation
DE3409079A1 (de) * 1984-03-13 1985-09-19 Bayer Ag, 5090 Leverkusen Medizinische pflaster
US5008111A (en) * 1984-10-11 1991-04-16 Schering Corporation Physiological means of enhancing transdermal delivery of drugs
US4824676A (en) * 1984-10-11 1989-04-25 Schering Corporation Physiological means of enhancing transdermal delivery of drugs
US4752478A (en) * 1984-12-17 1988-06-21 Merck & Co., Inc. Transdermal system for timolol
US4883669A (en) * 1985-02-25 1989-11-28 Rutgers, The State University Of New Jersey Transdermal absorption dosage unit for estradiol and other estrogenic steroids and process for administration
DE3518707A1 (de) * 1985-05-24 1986-11-27 Beiersdorf Ag, 2000 Hamburg Nitro-pflaster
AU610839B2 (en) * 1986-11-07 1991-05-30 Purepac, Inc Transdermal administration of amines
US5171576A (en) * 1987-03-09 1992-12-15 Alza Corporation Prevention of contact allergy by coadministration of a corticosteroid with a sensitizing drug
US5118509A (en) * 1987-03-09 1992-06-02 Alza Corporation Inducing skin tolerance to a sensitizing drug
US5049387A (en) * 1987-03-09 1991-09-17 Alza Corporation Inducing skin tolerance to a sensitizing drug
US5000956A (en) * 1987-03-09 1991-03-19 Alza Corporation Prevention of contact allergy by coadministration of a corticosteroid with a sensitizing drug
US5077054A (en) * 1987-03-09 1991-12-31 Alza Corporation Prevention of contact allergy by coadministration of a corticosteroid with a sensitizing drug
US4906475A (en) * 1988-02-16 1990-03-06 Paco Pharmaceutical Services Estradiol transdermal delivery system
US4885154A (en) * 1988-03-01 1989-12-05 Alza Corporation Method for reducing sensitization or irritation in transdermal drug delivery and means therefor
IL92496A0 (en) * 1988-12-01 1990-08-31 Schering Corp Compositions for transdermal delivery of estradiol
US4973468A (en) * 1989-03-22 1990-11-27 Cygnus Research Corporation Skin permeation enhancer compositions
US5053227A (en) * 1989-03-22 1991-10-01 Cygnus Therapeutic Systems Skin permeation enhancer compositions, and methods and transdermal systems associated therewith
US5059426A (en) * 1989-03-22 1991-10-22 Cygnus Therapeutic Systems Skin permeation enhancer compositions, and methods and transdermal systems associated therewith
US5091186A (en) * 1989-08-15 1992-02-25 Cygnus Therapeutic Systems Biphasic transdermal drug delivery device
US5160741A (en) * 1990-07-06 1992-11-03 Alza Corporation Reduction or prevention of skin irritation by drugs
US5130139A (en) * 1990-07-06 1992-07-14 Alza Corporation Reduction or prevention of skin irritation by drugs
US5149539A (en) * 1990-08-03 1992-09-22 Alza Corporation Reduction or prevention of sensitization to drugs
US5120545A (en) * 1990-08-03 1992-06-09 Alza Corporation Reduction or prevention of sensitization to drugs
US5512292A (en) * 1990-10-29 1996-04-30 Alza Corporation Transdermal contraceptive formulations methods and devices
US5202125A (en) * 1990-12-10 1993-04-13 Theratech, Inc. Method and systems for administering nitroglycerin transdermally at enhanced transdermal fluxes
IT1251469B (it) * 1991-07-15 1995-05-15 Zambon Spa Sistema terapeutico transdermale per la somministrazione di farmaci ad attivita' broncodilatante.
US5234690A (en) * 1991-08-23 1993-08-10 Cygnus Therapeutic Systems Transdermal drug delivery device using an unfilled microporous membrane to achieve delayed onset
US5273756A (en) * 1991-08-23 1993-12-28 Cygnus Therapeutic Systems Transdermal drug delivery device using a membrane-protected microporous membrane to achieve delayed onset
US5273755A (en) * 1991-08-23 1993-12-28 Cygnus Therapeutic Systems Transdermal drug delivery device using a polymer-filled microporous membrane to achieve delayed onset
JPH07503232A (ja) * 1991-10-18 1995-04-06 アルザ・コーポレーション メラトニンの制御経皮投与
JP3786684B2 (ja) * 1992-05-13 2006-06-14 アルザ・コーポレーション オキシブチニンの経皮投与
US5900250A (en) * 1992-05-13 1999-05-04 Alza Corporation Monoglyceride/lactate ester permeation enhancer for oxybutnin
US5989586A (en) * 1992-10-05 1999-11-23 Cygnus, Inc. Two-phase matrix for sustained release drug delivery device
US5613958A (en) * 1993-05-12 1997-03-25 Pp Holdings Inc. Transdermal delivery systems for the modulated administration of drugs
US5451407A (en) * 1993-06-21 1995-09-19 Alza Corporation Reduction or prevention of skin irritation or sensitization during transdermal administration of a irritating or sensitizing drug
ATE149349T1 (de) * 1993-06-25 1997-03-15 Alza Corp Einarbeitung eines poly-n-vinylamids in ein transdermales system
GB2281036A (en) * 1993-08-02 1995-02-22 Agri Tech Topical compositions containing polybutenes
ATE183926T1 (de) * 1993-09-29 1999-09-15 Alza Corp Hautpermeabilitaetserhöher bestehend aus monoglycerid/laktat estern
WO1996022083A1 (en) * 1995-01-19 1996-07-25 Cygnus, Inc. POLYISOBUTYLENE ADHESIVES CONTAINING HIGH Tg TACKIFIER FOR TRANSDERMAL DEVICES
US5785991A (en) * 1995-06-07 1998-07-28 Alza Corporation Skin permeation enhancer compositions comprising glycerol monolaurate and lauryl acetate
US6572879B1 (en) * 1995-06-07 2003-06-03 Alza Corporation Formulations for transdermal delivery of pergolide
US5840327A (en) * 1995-08-21 1998-11-24 Alza Corporation Transdermal drug delivery device having enhanced adhesion
US6512010B1 (en) * 1996-07-15 2003-01-28 Alza Corporation Formulations for the administration of fluoxetine
ATE229817T1 (de) * 1996-10-24 2003-01-15 Alza Corp Penetrationsfördernde substanzen für die transdermale verabreichung von wirkstoffen, vorrichtungen und verfahren zur herstellung
DE19654468C1 (de) * 1996-12-27 1998-01-22 Lohmann Therapie Syst Lts Extrem flexibles, dermal oder transdermal wirkendes Pflaster und Verfahren zu seiner Herstellung
US6203817B1 (en) 1997-02-19 2001-03-20 Alza Corporation Reduction of skin reactions caused by transdermal drug delivery
GB9711032D0 (en) * 1997-05-30 1997-07-23 Johnson Matthey Plc Compound as a stimulant for the central nervous system
AU756136B2 (en) 1997-06-23 2003-01-02 Queen's University At Kingston Microdose therapy
US5948433A (en) * 1997-08-21 1999-09-07 Bertek, Inc. Transdermal patch
US6660295B2 (en) 1997-09-30 2003-12-09 Alza Corporation Transdermal drug delivery device package with improved drug stability
AU1728099A (en) 1997-12-22 1999-07-12 Alza Corporation Monoglyceride and ethyl palmitate permeation enhancer compositions
DE19827732A1 (de) * 1998-06-22 1999-12-23 Rottapharm Bv Transdermales System vom Matrix-Typ zur Abgabe von Wirkstoffen mit einer hohen Abgaberate von Steroid-Hormonen und die Verwendung eines derartigen Systems zur Hormonersatztherapie
US6699497B1 (en) 1998-07-24 2004-03-02 Alza Corporation Formulations for the transdermal administration of fenoldopam
US6348210B1 (en) 1998-11-13 2002-02-19 Alza Corporation Methods for transdermal drug administration
DE69941629D1 (de) 1998-12-18 2009-12-17 Alza Corp Durchsichtige transdermale nicotinabgabevorrichtungen
DK1163019T3 (da) 1999-03-25 2008-03-03 Metabolix Inc Medicinske indretninger og anvendelser af polyhydroxyalkanoatpolymere
US6616942B1 (en) * 1999-03-29 2003-09-09 Soft Gel Technologies, Inc. Coenzyme Q10 formulation and process methodology for soft gel capsules manufacturing
ATE302598T1 (de) * 1999-04-01 2005-09-15 Alza Corp Transdermale vorrichtung zur arzneistoffverabreichung mit einem polyurethanwirkstoffreservoir
EP1212046A2 (en) 1999-08-30 2002-06-12 Tepha, Inc. Flushable disposable polymeric products
DE50009346D1 (de) * 1999-11-29 2005-03-03 Novosis Ag Transdermalsystem zur Abgabe von Clonidin
US6602912B2 (en) * 2000-06-30 2003-08-05 Dermatrends, Inc. Transdermal administration of phenylpropanolamine
DE10003767A1 (de) 2000-01-28 2001-10-04 Beiersdorf Ag Hautfreundliches Wirkstoffpflaster zur transdermalen Verabreichung nichtsteroidaler Antirheumatika
AT414205B (de) * 2000-06-20 2006-10-15 Vis Vitalis Lizenz & Handels Verfahren zur herstellung von ungesättigtem fettsäure-trockenkonzentrat
DE10033853A1 (de) * 2000-07-12 2002-01-31 Hexal Ag Transdermales therapeutisches System mit hochdispersem Siliziumdioxid
JP3962684B2 (ja) * 2000-11-06 2007-08-22 サムヤン コーポレイション 改善された水分吸収能および接着性を有する経皮投与剤
WO2002069906A2 (en) 2001-03-06 2002-09-12 Cellegy Pharmaceuticals, Inc. Compounds and methods for the treatment of urogenital disorders
AU2002343555A1 (en) 2001-11-14 2003-05-26 Texas Tech University Eutectic-based self-nanoemulsified drug delivery system
AT410633B (de) * 2002-04-25 2003-06-25 Oekopharm Forschungs Und Entwi Verwendung eines auf einer biologisch inerten, hochdispersen matrix getrockneten stutenmilchkonzentrats
IL152575A (en) * 2002-10-31 2008-12-29 Transpharma Medical Ltd A skin-to-skin transmission system of water-insoluble drugs
IL152573A (en) * 2002-10-31 2009-11-18 Transpharma Medical Ltd A system for the transmission through the skin of a medical preparation against vomiting and nausea
US20040258742A1 (en) * 2003-04-11 2004-12-23 Van Osdol William Woodson Transdermal administration of N-(2,5-disubstituted phenyl)-N'-(3-substituted phenyl)-N'-methyl guanidines
US20040208917A1 (en) * 2003-04-16 2004-10-21 Wilfried Fischer Transdermal systems for the release of clonidine
EP2860292B1 (en) 2003-05-08 2020-07-22 Tepha, Inc. Polyhydroxyalkanoate medical textiles and fibers
US20040237400A1 (en) * 2003-05-27 2004-12-02 Weder Donald E. Plant package with floral wrapper with decorative portion
WO2005025549A2 (en) * 2003-09-10 2005-03-24 Noven Pharmaceuticals, Inc. Multi-layer transdermal drug delivery device
AU2004277951B2 (en) 2003-09-29 2010-11-11 Soft Gel Technologies, Inc. Solubilized CoQ-10
US8124072B2 (en) 2003-09-29 2012-02-28 Soft Gel Technologies, Inc. Solubilized CoQ-10
NZ546992A (en) * 2003-10-28 2009-07-31 Noven Pharma Transdermal drug delivery device
DE10357321A1 (de) * 2003-12-05 2005-07-21 Tesa Ag Hochtackige Klebmasse, Verfahren zu deren Herstellung und deren Verwendung
US7105263B2 (en) * 2003-12-30 2006-09-12 Samsung Electronics Company Dry toner comprising encapsulated pigment, methods and uses
TWI239252B (en) * 2003-12-31 2005-09-11 Ind Tech Res Inst A patch and the manufacturing method of the same
US20060008432A1 (en) * 2004-07-07 2006-01-12 Sebastiano Scarampi Gilsonite derived pharmaceutical delivery compositions and methods: nail applications
ATE473021T1 (de) 2004-08-03 2010-07-15 Tepha Inc Nichtkräuselnde polyhydroxyalkanoatnähte
US8246976B2 (en) * 2004-10-08 2012-08-21 Noven Pharmaceuticals, Inc. Transdermal delivery of drugs based on crystal size
WO2006041911A2 (en) 2004-10-08 2006-04-20 Noven Pharmaceuticals, Inc. Device transdermal administration of drugs including acrylic polymers
MX2007004315A (es) * 2004-10-08 2008-03-11 Noven Pharma Dispositivo para suministro transdermico de farmaco que incluye un respaldo oclusivo.
WO2006041907A2 (en) 2004-10-08 2006-04-20 Noven Pharmaceuticals, Inc. Transdermal delivery of estradiol
US8252320B2 (en) 2004-10-21 2012-08-28 Durect Corporation Transdermal delivery system for sufentanil
US8246977B2 (en) 2004-10-21 2012-08-21 Durect Corporation Transdermal delivery systems
US7888422B2 (en) * 2005-11-09 2011-02-15 Mylan Technologies Inc. Long-wearing removable pressure sensitive adhesive
US8518926B2 (en) 2006-04-10 2013-08-27 Knopp Neurosciences, Inc. Compositions and methods of using (R)-pramipexole
US20070259930A1 (en) * 2006-04-10 2007-11-08 Knopp Neurosciences, Inc. Compositions and methods of using r(+) pramipexole
ES2379117T3 (es) 2006-05-16 2012-04-20 Knopp Neurosciences, Inc. Composiciones de R(+) y S(-) pramipexol y métodos de utilización de las mismas
CA2657332A1 (en) * 2006-07-14 2008-01-17 Wine, Harvey Transdermal formulations of synthetic cannabinoids and nano colloidal silica
EP2117521B1 (en) 2006-11-03 2012-06-27 Durect Corporation Transdermal delivery systems comprising bupivacaine
CN101190183B (zh) * 2006-11-29 2010-05-12 上海医药工业研究院 一种盐酸可乐定多泡脂质体及其制备方法
US7943683B2 (en) 2006-12-01 2011-05-17 Tepha, Inc. Medical devices containing oriented films of poly-4-hydroxybutyrate and copolymers
US8524695B2 (en) 2006-12-14 2013-09-03 Knopp Neurosciences, Inc. Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same
WO2008113056A2 (en) 2007-03-14 2008-09-18 Knopp Neurosciences, Inc. Synthesis of chirally purified substituted benzothiazole diamines
US8343541B2 (en) 2007-03-15 2013-01-01 Soft Gel Technologies, Inc. Ubiquinol and alpha lipoic acid compositions
US9017301B2 (en) * 2007-09-04 2015-04-28 Mylan Technologies, Inc. Transdermal drug delivery systems comprising a coated release liner
EP2111857A1 (de) * 2008-04-25 2009-10-28 Acino AG Transdermales therapeutisches System zur Verabreichung von Fentanyl oder einem Analogstoff hiervon
US8231906B2 (en) 2008-07-10 2012-07-31 Noven Pharmaceuticals, Inc. Transdermal estrogen device and delivery
CN102186350A (zh) 2008-08-19 2011-09-14 诺普神经科学股份有限公司 使用(r)-普拉克索的组合物与方法
US20110009460A1 (en) * 2009-06-19 2011-01-13 Valentin Gribkoff Compositions and methods for treating amyotrophic lateral sclerosis
CA2768646C (en) * 2009-07-21 2014-07-08 Mylan Inc. Process for the continuous manufacture of a polyisobutylene based transdermal patch
EP2295046B1 (de) * 2009-09-14 2012-12-19 Acino AG Transdermales therapeutisches System zur Verabreichung von Fentanyl oder einem Analogstoff davon
WO2012060431A1 (ja) 2010-11-02 2012-05-10 積水メディカル株式会社 貼付剤
US9114258B2 (en) 2011-01-04 2015-08-25 Kato Medical Systems Llc Electrokinetic nerve stimulator
EP3513787A1 (en) 2011-01-10 2019-07-24 Invion, Inc Use of beta-adrenergic inverse agonists for smoking cessation
WO2013096816A1 (en) 2011-12-22 2013-06-27 Biogen Idec Ma Inc. Improved synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds
CN103893155B (zh) * 2012-12-26 2018-11-06 江苏康倍得药业股份有限公司 一种药物透皮贴剂
US9072682B2 (en) * 2012-12-31 2015-07-07 Mylan Inc. Transdermal dosage form for low-melting point active agent
US9662313B2 (en) 2013-02-28 2017-05-30 Knopp Biosciences Llc Compositions and methods for treating amyotrophic lateral sclerosis in responders
EP2999444A4 (en) 2013-05-20 2016-10-12 Mylan Inc ADVANCED TRANSDERMAL DOSAGE OF PRAMIPEXOL FOR THE TREATMENT OF NEUROLOGICAL DISEASES
SMT202100119T1 (it) 2013-07-12 2021-05-07 Knopp Biosciences Llc Trattamento dei livelli elevati di eosinofili e/o basofili
US9468630B2 (en) 2013-07-12 2016-10-18 Knopp Biosciences Llc Compositions and methods for treating conditions related to increased eosinophils
AU2014306597B2 (en) 2013-08-13 2018-05-17 Knopp Biosciences Llc Compositions and methods for treating chronic urticaria
EP3038467B1 (en) 2013-08-13 2020-07-29 Knopp Biosciences LLC Compositions and methods for treating plasma cell disorders and b-cell prolymphocytic disorders
US20180271800A1 (en) 2017-03-24 2018-09-27 E Ink California, Llc Microcell systems for delivering active molecules
EP3180040B1 (en) 2014-08-15 2020-05-13 Tepha, Inc. Self-retaining sutures of poly-4-hydroxybutyrate and copolymers thereof
EP3197275B1 (en) 2014-09-24 2021-11-24 Pain Therapeutics, Inc. 4:3 naltrexone: 5-methyl-2-furaldehyde cocrystal
US9555155B2 (en) 2014-12-11 2017-01-31 Tepha, Inc. Methods of orienting multifilament yarn and monofilaments of poly-4-hydroxybutyrate and copolymers thereof
US10626521B2 (en) 2014-12-11 2020-04-21 Tepha, Inc. Methods of manufacturing mesh sutures from poly-4-hydroxybutyrate and copolymers thereof
EP3352822B1 (en) 2015-09-24 2022-07-27 Pain Therapeutics, Inc. Cocrystals of naloxone and naltrexone
TWI670089B (zh) 2017-03-24 2019-09-01 美商伊英克加利福尼亞有限責任公司 用於調節活性物投送速率之包含帶電或磁性粒子的微胞遞送系統
TWI714347B (zh) 2017-11-14 2020-12-21 美商伊英克加利福尼亞有限責任公司 包含多孔導電電極層之電泳主動遞送系統
EP4065209B1 (en) 2019-11-27 2025-06-11 E Ink Corporation Benefit agent delivery system comprising microcells having an electrically eroding sealing layer
CN116322881A (zh) 2020-10-29 2023-06-23 伊英克加利福尼亚有限责任公司 用于递送有益剂的微单元系统
CN116507322A (zh) 2020-10-29 2023-07-28 伊英克加利福尼亚有限责任公司 用于递送亲水活性分子的微单元系统

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2627938A (en) * 1948-08-10 1953-02-10 Res Prod Corp Method of making high viscosity products having petroleum oil base and product of such method
US2628205A (en) * 1950-10-21 1953-02-10 Res Prod Corp Viscous hydrophilic composition and method of making the same
US2775561A (en) * 1952-07-02 1956-12-25 Res Prod Corp Viscous composition and method of making the same
US3029188A (en) * 1958-02-20 1962-04-10 Olin Mathieson Gelatin adhesive pharmaceutical preparations
US3079299A (en) * 1959-11-16 1963-02-26 Gen Aerosol Corp Self-propelling medicinal ointment composition containing polyethylene and method ofapplication
CA758049A (en) * 1960-07-19 1967-05-02 The Gillette Company Heat-generating cosmetic composition
GB1050858A (enExample) * 1963-06-07
US3215599A (en) * 1963-07-02 1965-11-02 Warner Lambert Pharmaceutical Process for preparing polymer waxmodified petroleum oil unctuous base
US3400197A (en) * 1965-01-26 1968-09-03 Robins Co Inc A H Compressible sustained release pharmaceutical tablet lipid-colloidal silica gel matrix fragment granules
US3574827A (en) * 1966-12-29 1971-04-13 Exxon Research Engineering Co Ointment base composition
US3733403A (en) * 1970-01-26 1973-05-15 Squibb & Sons Inc Gelled mineral oil
US4262003A (en) * 1975-12-08 1981-04-14 Alza Corporation Method and therapeutic system for administering scopolamine transdermally
FR2435950A1 (fr) * 1978-06-05 1980-04-11 Riker Laboratories Inc Pansement medical comprenant une composition a base de nitroglycerine, sa fabrication et son application
US4291015A (en) * 1979-08-14 1981-09-22 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing a vasodilator
US4314557A (en) * 1980-05-19 1982-02-09 Alza Corporation Dissolution controlled active agent dispenser
US4725272A (en) * 1981-06-29 1988-02-16 Alza Corporation Novel bandage for administering beneficial drug

Also Published As

Publication number Publication date
ES532228A0 (es) 1985-10-16
IT1179635B (it) 1987-09-16
IT8467445A1 (it) 1985-11-03
AU558304B2 (en) 1987-01-22
SE8402389L (sv) 1984-11-05
FR2545357A1 (fr) 1984-11-09
NL190508C (nl) 1994-04-05
NL190508B (nl) 1993-11-01
KR840009035A (ko) 1984-12-24
SE463012B (sv) 1990-10-01
BE899444A (fr) 1984-08-16
JPS59206307A (ja) 1984-11-22
US4559222A (en) 1985-12-17
FR2545357B1 (fr) 1987-10-23
DE3416248A1 (de) 1984-11-08
NL8401262A (nl) 1984-12-03
GB8407741D0 (en) 1984-05-02
ES8600943A1 (es) 1985-10-16
ZA843037B (en) 1984-11-28
CH666190A5 (de) 1988-07-15
CA1217139A (en) 1987-01-27
IT8467445A0 (it) 1984-05-03
DE3416248C2 (de) 1993-10-28
KR890000650B1 (ko) 1989-03-22
JPH0460091B2 (enExample) 1992-09-25
GB2140019A (en) 1984-11-21
AU2717184A (en) 1984-11-08
SE8402389D0 (sv) 1984-05-03

Similar Documents

Publication Publication Date Title
GB2140019B (en) Matrix composition for transdermal drug delivery systems
GB2163347B (en) Transdermal drug delivery system
ZA857355B (en) Novel drug delivery system
GB8322007D0 (en) Pharmaceutical delivery system
AU576630B2 (en) Drug delivery system
IL71967A (en) Drug administration composition
EP0184910A3 (en) Device for controlled release drug delivery
DE3570594D1 (en) Closed drug delivery system
GB2140687B (en) Osmotic drug delivery system
GB2122487B (en) Elastomeric drug dermal delivery system
GB2243778B (en) Adhesive drug delivery composition
EP0237263A3 (en) Transdermal drug delivery system
IL87135A0 (en) Estradiol transdermal delivery system
GB8502156D0 (en) Drug delivery
PT80525B (en) Sustained release drug delivery device
DE3369468D1 (en) Osmotic drug delivery system
EP0177329A3 (en) Device for transdermal drug administration
AU564661B2 (en) Transdermal delivery system for administration of nitroglycerin
DE3565468D1 (en) Drug administering apparatus
EP0182502A3 (en) Drug delivery system
GB2146525B (en) Drug delivery system
IL79510A0 (en) Nitroglycerin transdermal delivery system
EP0182520A3 (en) Apparatus for iontophoretic drug delivery
EP0204831A4 (en) ADMINISTRATION SYSTEM FOR MEDICINAL PRODUCTS.
IL93143A0 (en) Transdermal drug delivery composition

Legal Events

Date Code Title Description
PE20 Patent expired after termination of 20 years

Effective date: 20040325