GB2051048B - Geminal dihalogen derivatives of condensed pyrimidin-4-one compounds their preparation and pharmaceutical compositions containing them - Google Patents

Geminal dihalogen derivatives of condensed pyrimidin-4-one compounds their preparation and pharmaceutical compositions containing them

Info

Publication number
GB2051048B
GB2051048B GB8015469A GB8015469A GB2051048B GB 2051048 B GB2051048 B GB 2051048B GB 8015469 A GB8015469 A GB 8015469A GB 8015469 A GB8015469 A GB 8015469A GB 2051048 B GB2051048 B GB 2051048B
Authority
GB
United Kingdom
Prior art keywords
compounds
preparation
pharmaceutical compositions
compositions containing
pyrimidin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB8015469A
Other languages
English (en)
Other versions
GB2051048A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chinoin Private Co Ltd
Original Assignee
Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt filed Critical Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Publication of GB2051048A publication Critical patent/GB2051048A/en
Application granted granted Critical
Publication of GB2051048B publication Critical patent/GB2051048B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B62/00—Reactive dyes, i.e. dyes which form covalent bonds with the substrates or which polymerise with themselves

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
GB8015469A 1979-05-11 1980-05-09 Geminal dihalogen derivatives of condensed pyrimidin-4-one compounds their preparation and pharmaceutical compositions containing them Expired GB2051048B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU79CI1932A HU179443B (en) 1979-05-11 1979-05-11 Process for producing substituted geminal dihalogeno-derivatives of pyrido-square bracket-1,2-a-square closed-pyrimidines,pyrrolo-square bracket-1,2-a-square bracket closed-pyrimidines and pyrimido-square bracket-1,2,-a-square bracket closed-asepines

Publications (2)

Publication Number Publication Date
GB2051048A GB2051048A (en) 1981-01-14
GB2051048B true GB2051048B (en) 1983-01-19

Family

ID=10994747

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8015469A Expired GB2051048B (en) 1979-05-11 1980-05-09 Geminal dihalogen derivatives of condensed pyrimidin-4-one compounds their preparation and pharmaceutical compositions containing them

Country Status (24)

Country Link
JP (1) JPS5615286A (es)
AT (1) AT377261B (es)
BE (1) BE883217A (es)
CA (1) CA1141379A (es)
CH (1) CH646971A5 (es)
CS (1) CS241025B2 (es)
DD (1) DD150605A5 (es)
DE (1) DE3017564A1 (es)
DK (1) DK204680A (es)
ES (1) ES491896A0 (es)
FI (1) FI68825C (es)
FR (1) FR2456101A1 (es)
GB (1) GB2051048B (es)
GR (1) GR68518B (es)
HU (1) HU179443B (es)
IL (1) IL59967A (es)
IT (1) IT1133085B (es)
LU (1) LU82437A1 (es)
NL (1) NL8002678A (es)
NO (1) NO152607C (es)
PL (1) PL124035B1 (es)
PT (1) PT71213A (es)
SE (1) SE441747B (es)
SU (1) SU1151210A3 (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9320707B2 (en) 1997-11-17 2016-04-26 Janssen Pharmaceutica, N.V. Aqueous suspensions of submicron 9-hydroxyrisperidone fatty acid esters

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU178453B (en) * 1979-05-11 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for producing 9-hydrazino-4-oxo-6,7,8,9-tetrahydro-4h-p-pyrido-square bracket-1,2-a-square bracket closed-pyrimidine derivatives
US4395549A (en) 1981-10-02 1983-07-26 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. 6-Hydrazono-pyrido[2,1-b] quinazoline-11 ones
ES8501397A1 (es) * 1982-08-05 1984-11-16 Erba Farmitalia "procedimiento para preparar derivados de quinazolina"
US5158952A (en) * 1988-11-07 1992-10-27 Janssen Pharmaceutica N.V. 3-[2-[4-(6-fluoro-1,2-benzisoxozol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9 tetrahydro-9-hydroxy-2-methyl-4H-pyrido [1,2-a]pyrimidin-4-one, compositions and method of use

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT286990B (de) * 1966-11-02 1971-01-11 Chinoin Gyogyszer Es Vegyeszet Verfahren zur Herstellung von neuen Homopyrimidazol-Derivaten sowie von deren Salzen
HU178496B (en) * 1977-12-29 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 6,7,8,9-tetrahydro-4h-pyrido/1,2-a/pyrimidine derivatives with antiallergic activity

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9320707B2 (en) 1997-11-17 2016-04-26 Janssen Pharmaceutica, N.V. Aqueous suspensions of submicron 9-hydroxyrisperidone fatty acid esters

Also Published As

Publication number Publication date
NO152607B (no) 1985-07-15
BE883217A (fr) 1980-09-01
DD150605A5 (de) 1981-09-09
IT8067719A0 (it) 1980-05-09
CS325880A2 (en) 1985-06-13
GR68518B (es) 1982-01-11
PL224163A1 (es) 1981-02-13
NL8002678A (nl) 1980-11-13
ATA247580A (de) 1984-07-15
CS241025B2 (en) 1986-03-13
DK204680A (da) 1980-11-12
NO801378L (no) 1980-11-12
LU82437A1 (fr) 1980-07-31
FR2456101A1 (fr) 1980-12-05
ES8102570A1 (es) 1981-02-16
FR2456101B1 (es) 1985-04-05
AT377261B (de) 1985-02-25
PL124035B1 (en) 1982-12-31
CH646971A5 (de) 1984-12-28
FI68825C (fi) 1985-11-11
CA1141379A (en) 1983-02-15
SU1151210A3 (ru) 1985-04-15
FI68825B (fi) 1985-07-31
PT71213A (en) 1980-06-01
NO152607C (no) 1985-10-23
JPS5615286A (en) 1981-02-14
SE8003479L (sv) 1980-11-12
IT1133085B (it) 1986-07-09
HU179443B (en) 1982-10-28
DE3017564A1 (de) 1980-11-13
FI801512A (fi) 1980-11-12
IL59967A0 (en) 1980-07-31
SE441747B (sv) 1985-11-04
GB2051048A (en) 1981-01-14
ES491896A0 (es) 1981-02-16
IL59967A (en) 1984-05-31

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee