GB2028318B - Spiro-oxazolidindiones - Google Patents

Spiro-oxazolidindiones

Info

Publication number
GB2028318B
GB2028318B GB7926348A GB7926348A GB2028318B GB 2028318 B GB2028318 B GB 2028318B GB 7926348 A GB7926348 A GB 7926348A GB 7926348 A GB7926348 A GB 7926348A GB 2028318 B GB2028318 B GB 2028318B
Authority
GB
United Kingdom
Prior art keywords
oxazolidindiones
spiro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB7926348A
Other languages
English (en)
Other versions
GB2028318A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of GB2028318A publication Critical patent/GB2028318A/en
Application granted granted Critical
Publication of GB2028318B publication Critical patent/GB2028318B/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D335/00Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06Benzothiopyrans; Hydrogenated benzothiopyrans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/12Ophthalmic agents for cataracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Dental Preparations (AREA)
  • Photosensitive Polymer And Photoresist Processing (AREA)
  • Moulding By Coating Moulds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
GB7926348A 1978-08-21 1979-07-27 Spiro-oxazolidindiones Expired GB2028318B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/935,199 US4200642A (en) 1978-08-21 1978-08-21 Spiro-oxazolidindiones

Publications (2)

Publication Number Publication Date
GB2028318A GB2028318A (en) 1980-03-05
GB2028318B true GB2028318B (en) 1982-08-04

Family

ID=25466700

Family Applications (2)

Application Number Title Priority Date Filing Date
GB7926348A Expired GB2028318B (en) 1978-08-21 1979-07-27 Spiro-oxazolidindiones
GB8001161A Expired GB2033904B (en) 1978-08-21 1979-08-27 Dihydrobenzopyrans and thiopyrans

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB8001161A Expired GB2033904B (en) 1978-08-21 1979-08-27 Dihydrobenzopyrans and thiopyrans

Country Status (34)

Country Link
US (1) US4200642A (US20100268047A1-20101021-C00003.png)
JP (4) JPS6011914B2 (US20100268047A1-20101021-C00003.png)
AR (1) AR225614A1 (US20100268047A1-20101021-C00003.png)
AT (1) AT366689B (US20100268047A1-20101021-C00003.png)
AU (1) AU535170B2 (US20100268047A1-20101021-C00003.png)
BE (1) BE878311A (US20100268047A1-20101021-C00003.png)
CA (1) CA1121361A (US20100268047A1-20101021-C00003.png)
CH (1) CH639974A5 (US20100268047A1-20101021-C00003.png)
CS (1) CS208129B2 (US20100268047A1-20101021-C00003.png)
DD (1) DD146602A5 (US20100268047A1-20101021-C00003.png)
DE (2) DE2933441A1 (US20100268047A1-20101021-C00003.png)
DK (1) DK258479A (US20100268047A1-20101021-C00003.png)
EG (1) EG14639A (US20100268047A1-20101021-C00003.png)
ES (1) ES483511A1 (US20100268047A1-20101021-C00003.png)
FI (1) FI65255C (US20100268047A1-20101021-C00003.png)
FR (3) FR2442851A1 (US20100268047A1-20101021-C00003.png)
GB (2) GB2028318B (US20100268047A1-20101021-C00003.png)
GR (1) GR71913B (US20100268047A1-20101021-C00003.png)
HU (1) HU179746B (US20100268047A1-20101021-C00003.png)
IE (1) IE48932B1 (US20100268047A1-20101021-C00003.png)
IL (1) IL58076A (US20100268047A1-20101021-C00003.png)
IN (1) IN152416B (US20100268047A1-20101021-C00003.png)
IT (1) IT1123536B (US20100268047A1-20101021-C00003.png)
LU (1) LU81613A1 (US20100268047A1-20101021-C00003.png)
NL (1) NL7906318A (US20100268047A1-20101021-C00003.png)
NO (1) NO792699L (US20100268047A1-20101021-C00003.png)
NZ (1) NZ191350A (US20100268047A1-20101021-C00003.png)
PH (1) PH18091A (US20100268047A1-20101021-C00003.png)
PL (1) PL130686B1 (US20100268047A1-20101021-C00003.png)
PT (1) PT70086A (US20100268047A1-20101021-C00003.png)
SE (1) SE447116B (US20100268047A1-20101021-C00003.png)
SU (1) SU942597A3 (US20100268047A1-20101021-C00003.png)
YU (1) YU41488B (US20100268047A1-20101021-C00003.png)
ZA (1) ZA794379B (US20100268047A1-20101021-C00003.png)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USD775790S1 (en) * 2015-11-18 2017-01-10 Ginger Damon Motorcycle jacket

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4329459A (en) * 1980-05-05 1982-05-11 The Upjohn Company Tetrahydrobenzopyran derivatives
US4367234A (en) * 1980-07-28 1983-01-04 Pfizer Inc. Hypoglycemic 5-substituted oxazolidine-2,4-diones
SG56656G (en) * 1980-07-28 1987-03-27 Pfizer Hypoglycemic 5-substituted oxazolidine-2, 4-diones
ES515751A0 (es) * 1981-10-13 1983-10-16 Pfizer "un procedimiento por analogia para la preparacion de derivados de espiro-oxindol-oxazolidindiona".
US4436745A (en) 1982-04-15 1984-03-13 Alcon Laboratories, Inc. Method of inhibiting aldose reductase activity
US4438272A (en) 1982-04-15 1984-03-20 Alcon Laboratories, Inc. Spiro-(fluoren-9,4'-imidazolidine)-2',5'-diones
US4540700A (en) * 1982-04-15 1985-09-10 Alcon Laboratories, Inc. Treatment of diabetic complications with certain spiro-imidazolidine-diones
US4464385A (en) * 1982-04-15 1984-08-07 Alcon Laboratories, Inc. Treatment of diabetic complications with hydantoins
ZA832679B (en) * 1982-05-07 1983-12-28 Ici Plc Indoline derivatives
US4430337A (en) * 1982-06-23 1984-02-07 Pfizer Inc. Alicyclic substituted oxazolidine-2,4-diones having hypoglycemic activity
US4556670A (en) * 1982-12-06 1985-12-03 Pfizer Inc. Spiro-3-hetero-azolones for treatment of diabetic complications
US4533667A (en) * 1983-05-25 1985-08-06 Pfizer Inc. Imidazolidinedione derivatives
US4464380A (en) * 1983-05-25 1984-08-07 Pfizer Inc. Imidazolidinedione derivatives
DK277484A (da) * 1983-06-23 1984-12-24 Hoffmann La Roche Thiazolidinderivater
JPS61200991A (ja) * 1985-03-04 1986-09-05 Sanwa Kagaku Kenkyusho:Kk スピロ―3―ヘテロアゾリジン化合物、その製法及びそれを有効成分とする糖尿病合併症の予防及び治療剤
DE3522791C1 (en) * 1985-06-26 1987-01-02 Ferroplast Gmbh Positioning wall for lagging a cavity to be filled with a hardenable material in mining or tunnelling
US4853410A (en) * 1986-01-17 1989-08-01 Pfizer Inc. Hydroxyacetic acid derivatives for the treatment of diabetic complications
US5039672A (en) * 1990-04-05 1991-08-13 Pfizer Inc. Heterocyclic compounds as aldose reductase inhibitors
US5068332A (en) * 1990-10-12 1991-11-26 American Home Products Corporation Alkylidene analogs of 1'-aminospiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrones useful as aldose reductase inhibitors
US5102886A (en) * 1990-10-12 1992-04-07 American Home Products Corporation 1'-aminospiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrones and analogs thereof useful as aldose reductase inhibitors
FR2707981B1 (fr) * 1993-07-20 1995-09-01 Adir Nouveaux dérivés de benzospiroalcène, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
CA2376919C (en) 1999-06-18 2008-11-04 Merck & Co., Inc. Arylthiazolidinedione and aryloxazolidinedione derivatives
AU770870B2 (en) 1999-06-18 2004-03-04 Merck & Co., Inc. Arylthiazolidinedione and aryloxazolidinedione derivatives
ITPI20060083A1 (it) * 2006-07-11 2008-01-12 Univ Pisa Derivati 2,2-dimetilcromanici 4-spiro-eterocicilici azotati (a 5 e 6 termini) n-sostituiti quali cardio-protettori nei confronti dell'insulto ischemico
WO2019125264A1 (en) 2017-12-21 2019-06-27 Essity Hygiene And Health Aktiebolag Absorbent article comprising strong channel sealing bonds
EP3727260B1 (en) 2017-12-21 2022-11-02 Essity Hygiene and Health Aktiebolag Absorbent article with channel sealings and method for manufacturing the absorbent article

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1204232B (de) * 1959-07-16 1965-11-04 Ncr Co Verfahren zur Herstellung von Derivaten von 3-Alkyl-3'-methyl-spiro[benzoxazolin-2, 2'-(2'H-1'-benzopyran)]
US3532744A (en) * 1967-07-28 1970-10-06 American Home Prod 1- and 2-amino substituted indane and tetralene carboxylic acids
US3821383A (en) * 1972-07-10 1974-06-28 Ayerst Mckenna & Harrison Compositions for and a method of treating diabetic complications
CA1088945A (en) * 1976-10-18 1980-11-04 Pfizer Limited Hydantoin derivatives as therapeutic agents

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USD775790S1 (en) * 2015-11-18 2017-01-10 Ginger Damon Motorcycle jacket

Also Published As

Publication number Publication date
DK258479A (da) 1980-02-22
CS208129B2 (en) 1981-08-31
IE791592L (en) 1980-02-21
DE2933441C2 (US20100268047A1-20101021-C00003.png) 1987-04-23
JPS55129279A (en) 1980-10-06
FI792567A (fi) 1980-02-22
CA1121361A (en) 1982-04-06
LU81613A1 (fr) 1980-04-21
DD146602A5 (de) 1981-02-18
NO792699L (no) 1980-02-22
JPS5943954B2 (ja) 1984-10-25
US4200642A (en) 1980-04-29
ZA794379B (en) 1980-08-27
PH18091A (en) 1985-03-20
DE2933441A1 (de) 1980-02-28
FR2440950B1 (US20100268047A1-20101021-C00003.png) 1981-06-12
ATA560579A (de) 1981-09-15
JPS6011915B2 (ja) 1985-03-28
FI65255B (fi) 1983-12-30
FR2442851A1 (fr) 1980-06-27
SE447116B (sv) 1986-10-27
SE7906949L (sv) 1980-02-22
IT1123536B (it) 1986-04-30
GB2033904A (en) 1980-05-29
GB2028318A (en) 1980-03-05
YU41488B (en) 1987-08-31
PL217881A1 (US20100268047A1-20101021-C00003.png) 1981-01-02
GB2033904B (en) 1982-08-04
IT7925182A0 (it) 1979-08-20
JPS55129280A (en) 1980-10-06
PT70086A (en) 1979-09-01
NZ191350A (en) 1984-04-27
BE878311A (fr) 1980-02-20
JPS5528996A (en) 1980-02-29
ES483511A1 (es) 1980-09-01
FR2440950A1 (fr) 1980-06-06
AU5009279A (en) 1980-02-28
FR2440949B1 (US20100268047A1-20101021-C00003.png) 1981-06-12
DE2953954A1 (US20100268047A1-20101021-C00003.png) 1982-09-02
JPS6011914B2 (ja) 1985-03-28
IN152416B (US20100268047A1-20101021-C00003.png) 1984-01-07
CH639974A5 (fr) 1983-12-15
NL7906318A (nl) 1980-02-25
GR71913B (US20100268047A1-20101021-C00003.png) 1983-08-16
JPS5946517B2 (ja) 1984-11-13
IL58076A (en) 1982-07-30
FI65255C (fi) 1984-04-10
PL130686B1 (en) 1984-08-31
DE2953954C2 (US20100268047A1-20101021-C00003.png) 1987-12-03
JPS55129288A (en) 1980-10-06
FR2442851B1 (US20100268047A1-20101021-C00003.png) 1983-06-17
IL58076A0 (en) 1979-12-30
FR2440949A1 (fr) 1980-06-06
AU535170B2 (en) 1984-03-08
AR225614A1 (es) 1982-04-15
EG14639A (en) 1985-03-31
YU199979A (en) 1983-06-30
AT366689B (de) 1982-04-26
HU179746B (en) 1982-12-28
SU942597A3 (ru) 1982-07-07
IE48932B1 (en) 1985-06-26

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19920727