GB201613054D0 - New compound and process - Google Patents

New compound and process

Info

Publication number
GB201613054D0
GB201613054D0 GBGB1613054.4A GB201613054A GB201613054D0 GB 201613054 D0 GB201613054 D0 GB 201613054D0 GB 201613054 A GB201613054 A GB 201613054A GB 201613054 D0 GB201613054 D0 GB 201613054D0
Authority
GB
United Kingdom
Prior art keywords
new compound
compound
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1613054.4A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Verona Pharma Ltd
Original Assignee
Verona Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Verona Pharma Ltd filed Critical Verona Pharma Ltd
Priority to GBGB1613054.4A priority Critical patent/GB201613054D0/en
Publication of GB201613054D0 publication Critical patent/GB201613054D0/en
Priority to US16/309,435 priority patent/US10710998B2/en
Priority to PCT/GB2017/052190 priority patent/WO2018020249A1/en
Priority to SI201730098T priority patent/SI3490988T1/sl
Priority to SM20190582T priority patent/SMT201900582T1/it
Priority to PL17748880T priority patent/PL3490988T3/pl
Priority to CN201780046788.1A priority patent/CN109641891B/zh
Priority to RS20191474A priority patent/RS59566B1/sr
Priority to HUE17748880A priority patent/HUE046509T2/hu
Priority to PT177488806T priority patent/PT3490988T/pt
Priority to DK17748880T priority patent/DK3490988T3/da
Priority to HRP20192109TT priority patent/HRP20192109T1/hr
Priority to TW106125312A priority patent/TWI739871B/zh
Priority to EP17748880.6A priority patent/EP3490988B1/en
Priority to ES17748880T priority patent/ES2751948T3/es
Priority to JP2019503748A priority patent/JP6985367B2/ja
Priority to KR1020197004436A priority patent/KR102396059B1/ko
Priority to LTEP17748880.6T priority patent/LT3490988T/lt
Priority to CY20191101046T priority patent/CY1122138T1/el
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
GBGB1613054.4A 2016-07-28 2016-07-28 New compound and process Ceased GB201613054D0 (en)

Priority Applications (19)

Application Number Priority Date Filing Date Title
GBGB1613054.4A GB201613054D0 (en) 2016-07-28 2016-07-28 New compound and process
LTEP17748880.6T LT3490988T (lt) 2016-07-28 2017-07-27 Naujas junginys ir gavimo būdas
HUE17748880A HUE046509T2 (hu) 2016-07-28 2017-07-27 Új vegyület és eljárás
DK17748880T DK3490988T3 (da) 2016-07-28 2017-07-27 Ny forbindelse og fremgangsmåde
SI201730098T SI3490988T1 (sl) 2016-07-28 2017-07-27 Nova spojina in postopek
SM20190582T SMT201900582T1 (it) 2016-07-28 2017-07-27 Nuovo composto e procedimento
PL17748880T PL3490988T3 (pl) 2016-07-28 2017-07-27 Nowy związek i sposób
CN201780046788.1A CN109641891B (zh) 2016-07-28 2017-07-27 新化合物和方法
RS20191474A RS59566B1 (sr) 2016-07-28 2017-07-27 Novo jedinjenje i postupak
US16/309,435 US10710998B2 (en) 2016-07-28 2017-07-27 Compound and process
PT177488806T PT3490988T (pt) 2016-07-28 2017-07-27 Novo composto e processo
PCT/GB2017/052190 WO2018020249A1 (en) 2016-07-28 2017-07-27 New compound and process
HRP20192109TT HRP20192109T1 (hr) 2016-07-28 2017-07-27 Novi spoj i proces
TW106125312A TWI739871B (zh) 2016-07-28 2017-07-27 新化合物及方法
EP17748880.6A EP3490988B1 (en) 2016-07-28 2017-07-27 New compound and process
ES17748880T ES2751948T3 (es) 2016-07-28 2017-07-27 Nuevo compuesto y proceso
JP2019503748A JP6985367B2 (ja) 2016-07-28 2017-07-27 新規化合物および方法
KR1020197004436A KR102396059B1 (ko) 2016-07-28 2017-07-27 신규 화합물 및 이의 제조방법
CY20191101046T CY1122138T1 (el) 2016-07-28 2019-10-04 Νεα ενωση και διαδικασια

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1613054.4A GB201613054D0 (en) 2016-07-28 2016-07-28 New compound and process

Publications (1)

Publication Number Publication Date
GB201613054D0 true GB201613054D0 (en) 2016-09-14

Family

ID=56936838

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1613054.4A Ceased GB201613054D0 (en) 2016-07-28 2016-07-28 New compound and process

Country Status (19)

Country Link
US (1) US10710998B2 (https=)
EP (1) EP3490988B1 (https=)
JP (1) JP6985367B2 (https=)
KR (1) KR102396059B1 (https=)
CN (1) CN109641891B (https=)
CY (1) CY1122138T1 (https=)
DK (1) DK3490988T3 (https=)
ES (1) ES2751948T3 (https=)
GB (1) GB201613054D0 (https=)
HR (1) HRP20192109T1 (https=)
HU (1) HUE046509T2 (https=)
LT (1) LT3490988T (https=)
PL (1) PL3490988T3 (https=)
PT (1) PT3490988T (https=)
RS (1) RS59566B1 (https=)
SI (1) SI3490988T1 (https=)
SM (1) SMT201900582T1 (https=)
TW (1) TWI739871B (https=)
WO (1) WO2018020249A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3231444T3 (pl) 2014-05-12 2020-05-18 Verona Pharma Plc Nowe leczenie
GB201502260D0 (en) 2015-02-11 2015-04-01 Verona Pharma Plc Salt of Pyrimido[6,1-A]Isoquinolin-4-one compound
HRP20251132T1 (hr) * 2020-01-17 2025-11-21 Lupin Limited Postupci, procesi i međuproizvodi za pripremu spojeva kromana
CN116917287A (zh) 2021-04-29 2023-10-20 苏州盛迪亚生物医药有限公司 异喹啉酮类化合物及其用途
TW202325301A (zh) * 2021-12-14 2023-07-01 大陸商海思科醫藥集團股份有限公司 三環稠雜環類pde3/4雙重抑制及其用途
GB202202297D0 (en) 2022-02-21 2022-04-06 Verona Pharma Plc Formulation production process
EP4378942A1 (en) 2022-12-02 2024-06-05 Sandoz AG Crystal form of a pde3/4 inhibitor
WO2025003643A1 (en) 2023-06-26 2025-01-02 Verona Pharma Plc Particulate composition comprising ensifetrine
AU2024309346C1 (en) 2023-06-26 2026-03-12 Verona Pharma Plc Particulate composition comprising ensifentrine
WO2025052119A1 (en) 2023-09-06 2025-03-13 Verona Pharma Plc Ensifentrine for use in treating chronic obstructive pulmonary disease (copd)
US20250249008A1 (en) 2024-02-07 2025-08-07 Verona Pharma Plc Pharmaceutical compositions of ensifentrine for chronic obstructive pulmonary disease
US20250249007A1 (en) 2024-02-07 2025-08-07 Verona Pharma Plc Pharmaceutical compositions of ensifentrine for chronic obstructive pulmonary disease
WO2025176871A1 (en) 2024-02-23 2025-08-28 Inke, S.A. Process for preparing pyrimido[6,1-a]isoquinoline-4-ones

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ185900A (en) 1976-12-10 1981-04-24 Hoechst Ag Pyrimido (6,1-a) isoquinolin-4-ones medicaments intermediate isoquinolines
FI64370C (fi) 1977-05-05 1983-11-10 Hoechst Ag Foerfarande foer framstaellning av terapeutiskt anvaendbara pyimido-(6,1-a)isokinolin-2-imino-4-onderivat
DE2847693A1 (de) 1978-11-03 1980-05-22 Hoechst Ag Verfahren zur herstellung von pyrimido-(6,1-a)-isochinolin-2-onen
DE3135831A1 (de) 1981-09-10 1983-04-28 Hoechst Ag, 6230 Frankfurt 9,10-substituierte 2-mesitylimino-3-alkyl-3,4,6,7-tetrahydro-2h-pyrimido(6,1-a)isochinolin-4-one, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
ZW6284A1 (en) 1983-05-05 1985-10-30 Hoffmann La Roche Novel pyrimidone derivatives
DE60005493T2 (de) 1999-03-31 2004-07-01 Vernalis Ltd., Wokingham Pyrimido[6,1-a]isochinolinonderivate
PH12013500261A1 (en) 2010-08-09 2013-03-04 Verona Pharma Plc Crystalline form of pyrimidio[6,1-a]isoquinolin-4-one compound
EP2968312B1 (en) 2013-03-15 2018-01-31 Verona Pharma PLC Drug combination
PL3231444T3 (pl) 2014-05-12 2020-05-18 Verona Pharma Plc Nowe leczenie
MY196072A (en) 2014-09-15 2023-03-13 Verona Pharma Plc Liquid Inhalation Formulation Comprising RPL554
GB201502260D0 (en) 2015-02-11 2015-04-01 Verona Pharma Plc Salt of Pyrimido[6,1-A]Isoquinolin-4-one compound

Also Published As

Publication number Publication date
JP2019527228A (ja) 2019-09-26
RS59566B1 (sr) 2019-12-31
SI3490988T1 (sl) 2019-11-29
ES2751948T3 (es) 2020-04-02
US20190330206A1 (en) 2019-10-31
CN109641891A (zh) 2019-04-16
EP3490988B1 (en) 2019-08-28
KR20190034231A (ko) 2019-04-01
EP3490988A1 (en) 2019-06-05
SMT201900582T1 (it) 2019-11-13
DK3490988T3 (da) 2019-10-28
TWI739871B (zh) 2021-09-21
US10710998B2 (en) 2020-07-14
JP6985367B2 (ja) 2021-12-22
LT3490988T (lt) 2019-10-10
HRP20192109T1 (hr) 2020-02-21
WO2018020249A1 (en) 2018-02-01
HUE046509T2 (hu) 2020-03-30
TW201806951A (zh) 2018-03-01
CN109641891B (zh) 2021-05-04
KR102396059B1 (ko) 2022-05-10
PL3490988T3 (pl) 2020-02-28
PT3490988T (pt) 2019-10-28
CY1122138T1 (el) 2020-11-25

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)