GB201604492D0 - Transfected t-cells and t-cell receptors for use in immunotherapy against cancers - Google Patents

Transfected t-cells and t-cell receptors for use in immunotherapy against cancers

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Publication number
GB201604492D0
GB201604492D0 GBGB1604492.7A GB201604492A GB201604492D0 GB 201604492 D0 GB201604492 D0 GB 201604492D0 GB 201604492 A GB201604492 A GB 201604492A GB 201604492 D0 GB201604492 D0 GB 201604492D0
Authority
GB
United Kingdom
Prior art keywords
transfected
cells
cell receptors
immunotherapy against
against cancers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1604492.7A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Immatics Biotechnologies GmbH
Original Assignee
Immatics Biotechnologies GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immatics Biotechnologies GmbH filed Critical Immatics Biotechnologies GmbH
Priority to GBGB1604492.7A priority Critical patent/GB201604492D0/en
Publication of GB201604492D0 publication Critical patent/GB201604492D0/en
Priority to PCT/EP2017/056260 priority patent/WO2017158103A1/en
Priority to JP2018548022A priority patent/JP7340127B2/ja
Priority to EP23218295.6A priority patent/EP4357454A3/en
Priority to MX2018011225A priority patent/MX2018011225A/es
Priority to EA201892021A priority patent/EA201892021A1/ru
Priority to CR20220248A priority patent/CR20220248A/es
Priority to NZ747154A priority patent/NZ747154B2/en
Priority to EP17710955.0A priority patent/EP3430030B1/en
Priority to DK17710955.0T priority patent/DK3430030T5/da
Priority to CN202310195423.2A priority patent/CN116731156A/zh
Priority to SG11201807868VA priority patent/SG11201807868VA/en
Priority to CA3017502A priority patent/CA3017502A1/en
Priority to MA043720A priority patent/MA43720A/fr
Priority to TW110149342A priority patent/TWI826891B/zh
Priority to KR1020217015786A priority patent/KR102457504B1/ko
Priority to MYPI2018703216A priority patent/MY189042A/en
Priority to MA43330A priority patent/MA43330B1/fr
Priority to CN201780017511.6A priority patent/CN108884136B/zh
Priority to KR1020187029016A priority patent/KR102259109B1/ko
Priority to TW106108700A priority patent/TWI764886B/zh
Priority to ES17710955T priority patent/ES2968802T3/es
Priority to FIEP17710955.0T priority patent/FI3430030T3/fi
Priority to US15/460,654 priority patent/US10538573B2/en
Priority to AU2017235467A priority patent/AU2017235467B2/en
Priority to CR20180492A priority patent/CR20180492A/es
Priority to PH12018501933A priority patent/PH12018501933A1/en
Priority to CL2018002648A priority patent/CL2018002648A1/es
Priority to IL261788A priority patent/IL261788A/en
Priority to CONC2018/0010811A priority patent/CO2018010811A2/es
Priority to US16/403,058 priority patent/US10626160B2/en
Priority to US16/813,248 priority patent/US10889629B2/en
Priority to US17/125,922 priority patent/US11945854B2/en
Priority to AU2021204753A priority patent/AU2021204753A1/en
Priority to JP2023039404A priority patent/JP7559120B2/ja
Priority to US18/581,947 priority patent/US20240279308A1/en
Priority to JP2024160597A priority patent/JP2025011091A/ja
Priority to AU2024266950A priority patent/AU2024266950A1/en
Ceased legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/7051T-cell receptor (TcR)-CD3 complex
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/17Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/10Cellular immunotherapy characterised by the cell type used
    • A61K40/11T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/30Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/31Chimeric antigen receptors [CAR]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/30Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/32T-cell receptors [TCR]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41Vertebrate antigens
    • A61K40/42Cancer antigens
    • A61K40/4267Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
    • A61K40/4268MAGE
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41Vertebrate antigens
    • A61K40/42Cancer antigens
    • A61K40/4267Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
    • A61K40/4269NY-ESO
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0636T lymphocytes
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • C12N5/12Fused cells, e.g. hybridomas
    • C12N5/16Animal cells
    • C12N5/163Animal cells one of the fusion partners being a B or a T lymphocyte
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/46Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
    • A61K2239/55Lung
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/46Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
    • A61K2239/57Skin; melanoma
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells

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  • General Engineering & Computer Science (AREA)
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  • Molecular Biology (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
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  • Crystallography & Structural Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
GBGB1604492.7A 2016-03-16 2016-03-16 Transfected t-cells and t-cell receptors for use in immunotherapy against cancers Ceased GB201604492D0 (en)

Priority Applications (38)

Application Number Priority Date Filing Date Title
GBGB1604492.7A GB201604492D0 (en) 2016-03-16 2016-03-16 Transfected t-cells and t-cell receptors for use in immunotherapy against cancers
CR20180492A CR20180492A (es) 2016-03-16 2017-03-16 Células t transfectadas y receptores de células t de utilidad en inmunoterapias contra el cáncer
CN201780017511.6A CN108884136B (zh) 2016-03-16 2017-03-16 用于癌症免疫治疗的转染t细胞和t细胞受体
KR1020187029016A KR102259109B1 (ko) 2016-03-16 2017-03-16 암에 대한 면역요법에서의 사용을 위하여 형질주입된 t 세포 및 t 세포 수용체
EP23218295.6A EP4357454A3 (en) 2016-03-16 2017-03-16 Transfected t-cells and t-cell receptors for use in immunotherapy against cancers
MX2018011225A MX2018011225A (es) 2016-03-16 2017-03-16 Celulas t transfectadas y receptores de celulas t de utilidad en inmunoterapias contra el cancer.
EA201892021A EA201892021A1 (ru) 2016-03-16 2017-03-16 Трансфицированные t-клетки и t-клеточные рецепторы для применения в иммунотерапии раковых заболеваний
CR20220248A CR20220248A (es) 2016-03-16 2017-03-16 Células t transfectadas y receptores de células t de utilidad en inmunoterapias contra el cáncer
NZ747154A NZ747154B2 (en) 2016-03-16 2017-03-16 Transfected t-cells and t-cell receptors for use in immunotherapy against cancers
EP17710955.0A EP3430030B1 (en) 2016-03-16 2017-03-16 Transfected t-cells and t-cell receptors for use in immunotherapy against cancers
DK17710955.0T DK3430030T5 (da) 2016-03-16 2017-03-16 Transficerede t-celler og t-cellereceptorer til anvendelse i immunoterapi mod cancer
ES17710955T ES2968802T3 (es) 2016-03-16 2017-03-16 Células T transfectadas y receptores de células T para su uso en inmunoterapia contra el cáncer
SG11201807868VA SG11201807868VA (en) 2016-03-16 2017-03-16 Transfected t-cells and t-cell receptors for use in immunotherapy against cancers
CA3017502A CA3017502A1 (en) 2016-03-16 2017-03-16 Transfected t-cells and t-cell receptors for use in immunotherapy against cancers
MA043720A MA43720A (fr) 2016-03-16 2017-03-16 Lymphocytes t transfectés et récepteurs de lymphocytes t destinés à être utilisés en immunothérapie contre des cancers
TW110149342A TWI826891B (zh) 2016-03-16 2017-03-16 轉染 t 細胞和 t 細胞受體用於癌症免疫治療
KR1020217015786A KR102457504B1 (ko) 2016-03-16 2017-03-16 암에 대한 면역요법에서의 사용을 위하여 형질주입된 t 세포 및 t 세포 수용체
MYPI2018703216A MY189042A (en) 2016-03-16 2017-03-16 Transfected t-cells and t-cell receptors for use in immunotherapy against cancers
MA43330A MA43330B1 (fr) 2016-03-16 2017-03-16 Lymphocytes t transfectés et récepteurs de lymphocytes t destinés à être utilisés en immunothérapie contre des cancers
PCT/EP2017/056260 WO2017158103A1 (en) 2016-03-16 2017-03-16 Transfected t-cells and t-cell receptors for use in immunotherapy against cancers
TW106108700A TWI764886B (zh) 2016-03-16 2017-03-16 轉染 t 細胞和 t 細胞受體用於癌症免疫治療
JP2018548022A JP7340127B2 (ja) 2016-03-16 2017-03-16 がんに対する免疫療法で使用するための形質移入t細胞およびt細胞受容体
CN202310195423.2A CN116731156A (zh) 2016-03-16 2017-03-16 用于癌症免疫治疗的转染t细胞和t细胞受体
FIEP17710955.0T FI3430030T3 (fi) 2016-03-16 2017-03-16 Transfektoituja t-soluja ja t-solureseptoreita käytettäviksi syöpien immunoterapiassa
US15/460,654 US10538573B2 (en) 2016-03-16 2017-03-16 Transfected T-cells and T-cell receptors for use in immunotherapy against cancers
AU2017235467A AU2017235467B2 (en) 2016-03-16 2017-03-16 Transfected T-cells and T-cell receptors for use in immunotherapy against cancers
PH12018501933A PH12018501933A1 (en) 2016-03-16 2018-09-10 Transfected t-cells and t-cell receptors for use in immunotherapy against cancers
CL2018002648A CL2018002648A1 (es) 2016-03-16 2018-09-14 Células t transfectadas y receptores de células t de utilidad en inmunoterapias contra el cáncer
IL261788A IL261788A (en) 2016-03-16 2018-09-15 Nucleic acid-treated t-cells and receptor t-cells for use in immunotherapy against types of cancer
CONC2018/0010811A CO2018010811A2 (es) 2016-03-16 2018-10-09 Células t transfectadas y receptores de células t de utilidad en inmunoterapias contra el cáncer
US16/403,058 US10626160B2 (en) 2016-03-16 2019-05-03 Transfected T-cells and T-cell receptors for use in immunotherapy against cancers
US16/813,248 US10889629B2 (en) 2016-03-16 2020-03-09 Transfected T-cells and T-cell receptors for use in immunotherapy against cancers
US17/125,922 US11945854B2 (en) 2016-03-16 2020-12-17 Transfected T-cells and T-cell receptors for use in immunotherapy against cancers
AU2021204753A AU2021204753A1 (en) 2016-03-16 2021-07-07 Transfected t-cells and t-cell receptors for use in immunotherapy against cancers
JP2023039404A JP7559120B2 (ja) 2016-03-16 2023-03-14 がんに対する免疫療法で使用するための形質移入t細胞およびt細胞受容体
US18/581,947 US20240279308A1 (en) 2016-03-16 2024-02-20 Transfected t-cells and t-cell receptors for use in immunotherapy against cancers
JP2024160597A JP2025011091A (ja) 2016-03-16 2024-09-18 がんに対する免疫療法で使用するための形質移入t細胞およびt細胞受容体
AU2024266950A AU2024266950A1 (en) 2016-03-16 2024-11-28 Transfected t-cells and t-cell receptors for use in immunotherapy against cancers

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1604492.7A GB201604492D0 (en) 2016-03-16 2016-03-16 Transfected t-cells and t-cell receptors for use in immunotherapy against cancers

Publications (1)

Publication Number Publication Date
GB201604492D0 true GB201604492D0 (en) 2016-04-27

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1604492.7A Ceased GB201604492D0 (en) 2016-03-16 2016-03-16 Transfected t-cells and t-cell receptors for use in immunotherapy against cancers

Country Status (16)

Country Link
US (1) US10538573B2 (enExample)
EP (1) EP3430030B1 (enExample)
JP (1) JP7340127B2 (enExample)
KR (2) KR102259109B1 (enExample)
CN (1) CN108884136B (enExample)
AU (2) AU2017235467B2 (enExample)
CA (1) CA3017502A1 (enExample)
CR (1) CR20180492A (enExample)
EA (1) EA201892021A1 (enExample)
GB (1) GB201604492D0 (enExample)
MA (2) MA43330B1 (enExample)
MX (1) MX2018011225A (enExample)
MY (1) MY189042A (enExample)
SG (1) SG11201807868VA (enExample)
TW (1) TWI764886B (enExample)
WO (1) WO2017158103A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111533798A (zh) * 2017-04-10 2020-08-14 伊玛提克斯生物技术有限公司 用于癌症免疫治疗的肽及其肽组合物

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WO2016126882A1 (en) 2015-02-04 2016-08-11 Twist Bioscience Corporation Methods and devices for de novo oligonucleic acid assembly
US9981239B2 (en) 2015-04-21 2018-05-29 Twist Bioscience Corporation Devices and methods for oligonucleic acid library synthesis
IL258164B (en) 2015-09-18 2022-09-01 Twist Bioscience Corp Methods for modulating protein and cellular activity and method for nucleic acid synthesis
CN108698012A (zh) 2015-09-22 2018-10-23 特韦斯特生物科学公司 用于核酸合成的柔性基底
CN115920796A (zh) 2015-12-01 2023-04-07 特韦斯特生物科学公司 功能化表面及其制备
CN116731156A (zh) * 2016-03-16 2023-09-12 伊玛提克斯生物技术有限公司 用于癌症免疫治疗的转染t细胞和t细胞受体
GB201604458D0 (en) 2016-03-16 2016-04-27 Immatics Biotechnologies Gmbh Peptides and combination of peptides for use in immunotherapy against cancers
SG11201901563UA (en) 2016-08-22 2019-03-28 Twist Bioscience Corp De novo synthesized nucleic acid libraries
JP6871364B2 (ja) 2016-09-21 2021-05-12 ツイスト バイオサイエンス コーポレーション 核酸に基づくデータ保存
PT3551221T (pt) 2016-12-08 2022-01-18 Immatics Biotechnologies Gmbh Novos recetores de células t e imunoterapia empregando os mesmos
DE102016123847B3 (de) * 2016-12-08 2018-04-05 Immatics Biotechnologies Gmbh Neue T-Zellrezeptoren und deren Verwendung in Immuntherapie
AU2017378492B2 (en) * 2016-12-16 2022-06-16 Twist Bioscience Corporation Variant libraries of the immunological synapse and synthesis thereof
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