GB1578266A - Azatetracyclic compounds - Google Patents

Azatetracyclic compounds Download PDF

Info

Publication number
GB1578266A
GB1578266A GB21304/77A GB2130477A GB1578266A GB 1578266 A GB1578266 A GB 1578266A GB 21304/77 A GB21304/77 A GB 21304/77A GB 2130477 A GB2130477 A GB 2130477A GB 1578266 A GB1578266 A GB 1578266A
Authority
GB
United Kingdom
Prior art keywords
lower alkyl
mole
dibenzo
azepine
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB21304/77A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of GB1578266A publication Critical patent/GB1578266A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/32—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems containing carbocyclic rings other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D313/14—[b,f]-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/74—Naphthothiophenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02—Seven-membered rings
    • C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D337/14—[b,f]-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
    • C07C2603/26—Phenanthrenes; Hydrogenated phenanthrenes

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
GB21304/77A 1976-05-26 1977-05-20 Azatetracyclic compounds Expired GB1578266A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH665076A CH624105A5 (en) 1976-05-26 1976-05-26 Process for the preparation of novel azatetracyclic compounds

Publications (1)

Publication Number Publication Date
GB1578266A true GB1578266A (en) 1980-11-05

Family

ID=4312888

Family Applications (1)

Application Number Title Priority Date Filing Date
GB21304/77A Expired GB1578266A (en) 1976-05-26 1977-05-20 Azatetracyclic compounds

Country Status (30)

Country Link
JP (1) JPS52144687A (el)
AR (2) AR227608A1 (el)
AT (1) AT356114B (el)
AU (1) AU510471B2 (el)
BE (1) BE855009A (el)
CA (1) CA1104566A (el)
CH (2) CH624105A5 (el)
CS (2) CS225106B2 (el)
CY (1) CY1211A (el)
DD (1) DD131169A5 (el)
DE (1) DE2723105A1 (el)
DK (1) DK150301C (el)
ES (1) ES459070A1 (el)
FI (1) FI64582C (el)
FR (1) FR2352816A1 (el)
GB (1) GB1578266A (el)
GR (1) GR72092B (el)
HK (1) HK8784A (el)
HU (1) HU177417B (el)
IE (1) IE45204B1 (el)
IL (1) IL52168A (el)
KE (1) KE3339A (el)
MY (1) MY8500099A (el)
NL (1) NL7705707A (el)
NO (1) NO148489C (el)
NZ (1) NZ184191A (el)
PT (1) PT66588B (el)
SE (1) SE427354B (el)
SG (1) SG63683G (el)
ZA (1) ZA773161B (el)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0030916B1 (de) * 1979-12-10 1984-08-29 Ciba-Geigy Ag Azatetracyclische Carbonitrile

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL178593C (nl) * 1974-01-31 1986-04-16 Akzo Nv Werkwijze ter bereiding van een farmaceutisch preparaat op basis van een tetracyclische verbinding en werkwijze voor de bereiding van de daarbij te gebruiken tetracyclische verbindingen.
CH592095A5 (el) * 1974-02-22 1977-10-14 Ciba Geigy Ag

Also Published As

Publication number Publication date
CH624106A5 (en) 1981-07-15
FI64582B (fi) 1983-08-31
PT66588A (en) 1977-06-01
DK150301B (da) 1987-02-02
IL52168A0 (en) 1977-07-31
FI771651A (el) 1977-11-27
IL52168A (en) 1981-07-31
DE2723105A1 (de) 1977-12-15
FI64582C (fi) 1983-12-12
CS225103B2 (en) 1984-02-13
NO771830L (no) 1977-11-29
NZ184191A (en) 1979-12-11
DD131169A5 (de) 1978-06-07
SG63683G (en) 1984-07-27
GR72092B (el) 1983-09-13
FR2352816A1 (fr) 1977-12-23
JPH0141627B2 (el) 1989-09-06
NO148489B (no) 1983-07-11
IE45204B1 (en) 1982-07-14
ATA372577A (de) 1979-09-15
SE427354B (sv) 1983-03-28
IE45204L (en) 1977-11-26
AU2547377A (en) 1978-11-30
PT66588B (en) 1978-10-23
NL7705707A (nl) 1977-11-29
KE3339A (en) 1983-11-25
ES459070A1 (es) 1978-04-16
HK8784A (en) 1984-02-10
AR227608A1 (es) 1982-11-30
SE7706120L (sv) 1977-11-27
FR2352816B1 (el) 1980-01-18
AT356114B (de) 1980-04-10
CY1211A (en) 1984-04-06
AR228124A1 (es) 1983-01-31
JPS52144687A (en) 1977-12-02
DK150301C (da) 1988-01-04
DE2723105C2 (el) 1987-03-12
HU177417B (en) 1981-10-28
AU510471B2 (en) 1980-06-26
DK229977A (da) 1977-11-27
ZA773161B (en) 1978-04-26
CS225106B2 (en) 1984-02-13
MY8500099A (en) 1985-12-31
BE855009A (fr) 1977-11-25
NO148489C (no) 1983-10-19
CA1104566A (en) 1981-07-07
CH624105A5 (en) 1981-07-15

Similar Documents

Publication Publication Date Title
WO2002074746A1 (fr) Derives de benzazepine
EP0503844B1 (en) Thienopyridine derivatives and pharmaceutical compositions containing them
CS9101168A2 (en) Pharmaceutical mixtures and method of their active substance production
EP0990650A1 (en) Tricyclic pyrrole or pyrazole derivatives
WO2007140213A1 (en) Pyridoazepine derivatives
EP0216247A2 (en) Use of alpha 2 adrenergic receptor antagonists for the production of pharmaceutical compositions for treating colonic spasm, irritable bowel syndrome and constipation and process for preparing such pharmaceutical compositions
EP0005365B1 (en) Pyrano and thiopyrano (3,4-b) indole derivatives, processes for their preparation and pharmaceutical compositions containing them
US3962248A (en) Process for making 11-piperazino-diazepines, oxazepines, thiazepines and azepines
US4132709A (en) [2]Benzopyrano[4,3-c]pyridine derivatives and process therefor
US3636045A (en) Thiepino and oxepino(4 5-c)pyrrol derivatives
US3636046A (en) Derivatives of dibenzo(b f)pyrrolo(3 4-d)azepine
GB1578266A (en) Azatetracyclic compounds
US4707476A (en) Treating states of agitation with azatetracyclic compounds
KR20010022658A (ko) 3-치환된 3,4,5,7-테트라히드로-피롤로[3'4':4,5]티에노[2,3-ｄ]피리미딘 유도체, 그의 제법 및 5ｈｔ길항제로서의 용도
WO2002015934A1 (fr) Agents prophylactiques et remedes contre des maladies du systeme nerveux central
NZ220955A (en) Substituted hexahydroheteroarylquinolizines and pharmaceutical compositions containing such
WO2002002530A1 (fr) Antagoniste de gpr14
US3980797A (en) Hexahydro-diazepino-indole derivatives
IE43727B1 (en) Dibenzo/b,e//1,4/diazepines
US4263315A (en) Azatetracyclic carbonitriles
AT356119B (de) Verfahren zur herstellung von neuen azepin- derivaten und deren saeureadditionssalzen und isomeren
AU612495B2 (en) Condensed diazepinones
US3772348A (en) Derivatives of dibenzo(b,f)pyrrolo(3,4-d)azepine as cns-depressants
US3682959A (en) BENZOTHIEPINO{8 4,5-c{9 {0 PYRROLES
US4492691A (en) Azatetracyclic carbonitriles

Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
704A Declaration that licence is not available as of right for an excepted use (par. 4a/1977)
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19940520