CS225106B2 - The production of new tetrahyro-and hexahydro-aza-tetra cyclic compounds - Google Patents

The production of new tetrahyro-and hexahydro-aza-tetra cyclic compounds Download PDF

Info

Publication number
CS225106B2
CS225106B2 CS782988A CS298877A CS225106B2 CS 225106 B2 CS225106 B2 CS 225106B2 CS 782988 A CS782988 A CS 782988A CS 298877 A CS298877 A CS 298877A CS 225106 B2 CS225106 B2 CS 225106B2
Authority
CS
Czechoslovakia
Prior art keywords
radical
formula
group
alkyl
carbon atoms
Prior art date
Application number
CS782988A
Other languages
Czech (cs)
English (en)
Inventor
Hans Blattner
Angelo Dr Storni
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of CS225106B2 publication Critical patent/CS225106B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/32—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems containing carbocyclic rings other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D313/14—[b,f]-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/74—Naphthothiophenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02—Seven-membered rings
    • C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D337/14—[b,f]-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
    • C07C2603/26—Phenanthrenes; Hydrogenated phenanthrenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
CS782988A 1976-05-26 1977-05-26 The production of new tetrahyro-and hexahydro-aza-tetra cyclic compounds CS225106B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH665076A CH624105A5 (en) 1976-05-26 1976-05-26 Process for the preparation of novel azatetracyclic compounds

Publications (1)

Publication Number Publication Date
CS225106B2 true CS225106B2 (en) 1984-02-13

Family

ID=4312888

Family Applications (2)

Application Number Title Priority Date Filing Date
CS782988A CS225106B2 (en) 1976-05-26 1977-05-26 The production of new tetrahyro-and hexahydro-aza-tetra cyclic compounds
CS773475A CS225103B2 (en) 1976-05-26 1977-05-26 The production of new tetrahydro-and hexahydro-aza-tetracyclic compounds

Family Applications After (1)

Application Number Title Priority Date Filing Date
CS773475A CS225103B2 (en) 1976-05-26 1977-05-26 The production of new tetrahydro-and hexahydro-aza-tetracyclic compounds

Country Status (30)

Country Link
JP (1) JPS52144687A (el)
AR (2) AR227608A1 (el)
AT (1) AT356114B (el)
AU (1) AU510471B2 (el)
BE (1) BE855009A (el)
CA (1) CA1104566A (el)
CH (2) CH624105A5 (el)
CS (2) CS225106B2 (el)
CY (1) CY1211A (el)
DD (1) DD131169A5 (el)
DE (1) DE2723105A1 (el)
DK (1) DK150301C (el)
ES (1) ES459070A1 (el)
FI (1) FI64582C (el)
FR (1) FR2352816A1 (el)
GB (1) GB1578266A (el)
GR (1) GR72092B (el)
HK (1) HK8784A (el)
HU (1) HU177417B (el)
IE (1) IE45204B1 (el)
IL (1) IL52168A (el)
KE (1) KE3339A (el)
MY (1) MY8500099A (el)
NL (1) NL7705707A (el)
NO (1) NO148489C (el)
NZ (1) NZ184191A (el)
PT (1) PT66588B (el)
SE (1) SE427354B (el)
SG (1) SG63683G (el)
ZA (1) ZA773161B (el)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3069086D1 (de) * 1979-12-10 1984-10-04 Ciba Geigy Ag Azatetracyclic carbonitriles

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL178593C (nl) * 1974-01-31 1986-04-16 Akzo Nv Werkwijze ter bereiding van een farmaceutisch preparaat op basis van een tetracyclische verbinding en werkwijze voor de bereiding van de daarbij te gebruiken tetracyclische verbindingen.
CH592095A5 (el) * 1974-02-22 1977-10-14 Ciba Geigy Ag

Also Published As

Publication number Publication date
IL52168A0 (en) 1977-07-31
HU177417B (en) 1981-10-28
FR2352816A1 (fr) 1977-12-23
AU2547377A (en) 1978-11-30
JPS52144687A (en) 1977-12-02
GB1578266A (en) 1980-11-05
CY1211A (en) 1984-04-06
HK8784A (en) 1984-02-10
ES459070A1 (es) 1978-04-16
NZ184191A (en) 1979-12-11
ZA773161B (en) 1978-04-26
FI64582C (fi) 1983-12-12
CH624106A5 (en) 1981-07-15
CS225103B2 (en) 1984-02-13
CH624105A5 (en) 1981-07-15
CA1104566A (en) 1981-07-07
IE45204L (en) 1977-11-26
DK150301B (da) 1987-02-02
JPH0141627B2 (el) 1989-09-06
PT66588B (en) 1978-10-23
DK229977A (da) 1977-11-27
PT66588A (en) 1977-06-01
SE427354B (sv) 1983-03-28
DE2723105A1 (de) 1977-12-15
FI771651A (el) 1977-11-27
AU510471B2 (en) 1980-06-26
AT356114B (de) 1980-04-10
KE3339A (en) 1983-11-25
DK150301C (da) 1988-01-04
NO771830L (no) 1977-11-29
SG63683G (en) 1984-07-27
BE855009A (fr) 1977-11-25
SE7706120L (sv) 1977-11-27
FI64582B (fi) 1983-08-31
AR227608A1 (es) 1982-11-30
GR72092B (el) 1983-09-13
NL7705707A (nl) 1977-11-29
MY8500099A (en) 1985-12-31
ATA372577A (de) 1979-09-15
IE45204B1 (en) 1982-07-14
DE2723105C2 (el) 1987-03-12
NO148489B (no) 1983-07-11
DD131169A5 (de) 1978-06-07
FR2352816B1 (el) 1980-01-18
NO148489C (no) 1983-10-19
IL52168A (en) 1981-07-31
AR228124A1 (es) 1983-01-31

Similar Documents

Publication Publication Date Title
EP0210840B1 (en) Substituted imidazolylmethyltetrahydro-carbazolones
DK157868B (da) Analogifremgangsmaade til fremstilling af tetracykliske forbindelser
EP0990650A1 (en) Tricyclic pyrrole or pyrazole derivatives
NZ196446A (en) Dibenzoimidazo(az,oxaz or thiaz)epines
EP0046666A1 (en) 2(3H)-indolones, process for their preparation and compositions containing them
US4434171A (en) Dibenzazepine derivatives, pharmaceutical compositions containing them, and pharmaceutical methods using them
EP0005365B1 (en) Pyrano and thiopyrano (3,4-b) indole derivatives, processes for their preparation and pharmaceutical compositions containing them
EP0216247A2 (en) Use of alpha 2 adrenergic receptor antagonists for the production of pharmaceutical compositions for treating colonic spasm, irritable bowel syndrome and constipation and process for preparing such pharmaceutical compositions
EP0033767B1 (en) Indolobenzoxazines, processes for preparing and pharmaceutical compositions containing the same
HU189275B (en) Process for preparing azepino-indole derivatives and pharmaceutical compositions containing such compounds
US3373168A (en) Certain benzazepinoxyridoindole compounds and their preparation
KR20010022658A (ko) 3-치환된 3,4,5,7-테트라히드로-피롤로[3'4':4,5]티에노[2,3-ｄ]피리미딘 유도체, 그의 제법 및 5ｈｔ길항제로서의 용도
US4057560A (en) 1,2,2A,3,4,5 Hexahydrobenz[c,d]indol-1-yl-2-guanidines
CS225106B2 (en) The production of new tetrahyro-and hexahydro-aza-tetra cyclic compounds
US4309348A (en) Tricyclic indole derivatives
GB1599907A (en) Isoindolines
GB2030133A (en) Tetrahydrothiopyrano (2,3-b) indole derivatives
HU201759B (en) Process for producing new condensed diazepinones and pharmaceutical compositions comprising same
IE58689B1 (en) Piperazin-1-yl-ergoline derivatives, process for preparing them and pharmaceutical compositions containing them
PT97570A (pt) Processo para a preparacao de derivados de benzotienopiridina
NZ280734A (en) Thieno[2,3-d]pyrrolo[1,2-a]pyrrole, thieno[3,2-d]-pyrrolo[1,2-a]pyrrole, and pyrrolo[1,2-a]indole derivatives
US4002638A (en) Benzazepine derivatives
US4235903A (en) 1-Hydroxyalkanamine tetrahydrocarbazoles and cyclopent[b]indoles, compositions and method of use
US3957819A (en) 2-(halo alkylamino)-3-phenyl-3h-indole-3-ols
US3457271A (en) 11-lower alkyl-hexahydro-1-benzazepino (3,2,1-h,i)pyrido(4,3-b)indole