GB1553429A - 4-thia-1-azabicyclo(4.2.0)oct-2-ene derivatives - Google Patents

4-thia-1-azabicyclo(4.2.0)oct-2-ene derivatives

Info

Publication number
GB1553429A
GB1553429A GB15246/76A GB1524676A GB1553429A GB 1553429 A GB1553429 A GB 1553429A GB 15246/76 A GB15246/76 A GB 15246/76A GB 1524676 A GB1524676 A GB 1524676A GB 1553429 A GB1553429 A GB 1553429A
Authority
GB
United Kingdom
Prior art keywords
formula
compounds
protective group
meaning stated
substituents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB15246/76A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline LLC
Original Assignee
SmithKline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Corp filed Critical SmithKline Corp
Publication of GB1553429A publication Critical patent/GB1553429A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/085Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/36One oxygen atom
    • C07D263/38One oxygen atom attached in position 2
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
GB15246/76A 1975-05-05 1976-05-05 4-thia-1-azabicyclo(4.2.0)oct-2-ene derivatives Expired GB1553429A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57422575A 1975-05-05 1975-05-05
US62668675A 1975-10-29 1975-10-29

Publications (1)

Publication Number Publication Date
GB1553429A true GB1553429A (en) 1979-09-26

Family

ID=27076332

Family Applications (2)

Application Number Title Priority Date Filing Date
GB15246/76A Expired GB1553429A (en) 1975-05-05 1976-05-05 4-thia-1-azabicyclo(4.2.0)oct-2-ene derivatives
GB991/79A Expired GB1553430A (en) 1975-05-05 1976-05-05 Azetidine compounds

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB991/79A Expired GB1553430A (en) 1975-05-05 1976-05-05 Azetidine compounds

Country Status (11)

Country Link
JP (1) JPS51136694A (es)
AU (1) AU500636B2 (es)
CH (3) CH623331A5 (es)
DE (1) DE2619458A1 (es)
DK (1) DK194776A (es)
ES (3) ES447577A1 (es)
FR (2) FR2324639A1 (es)
GB (2) GB1553429A (es)
IE (1) IE43845B1 (es)
LU (1) LU74873A1 (es)
NL (1) NL7604797A (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4122086A (en) * 1977-07-26 1978-10-24 Smithkline Corporation Isopenicillins
FR2505840A1 (fr) * 1981-05-13 1982-11-19 Roussel Uclaf Nouveaux produits derives de l'acide 2-amino thiazolyl 2-oxyimino acetamido bicyclo-octene carboxylique, leur procede de preparation et leur application comme medicaments
FR2552089B2 (fr) * 1981-05-13 1985-10-25 Roussel Uclaf Nouveaux produits derives de l'acide 2-amino thiazolyl 2-oxyimino acetamido bicyclo-octene carboxylique, leur procede de preparation et leur application comme medicaments
CA1262128A (en) * 1981-08-27 1989-10-03 Christian N. Hubschwerlen .beta.-lactams
FR2538389B2 (fr) * 1981-10-23 1986-05-16 Roussel Uclaf Nouveaux produits derives de l'acide 3-amino 2-oxo azetidine-1-sulfamique, nouveau procede de preparation de produits optiquement actifs, application des nouveaux produits comme medicaments et produits necessaires a leur preparation
FR2515182B1 (fr) * 1981-10-23 1986-05-09 Roussel Uclaf Nouveaux produits derives de l'acide 3-amino 2-oxo azetidine 1-sulfamique, leur procede de preparation, leur application comme medicaments et les produits intermediaires necessaires a leur preparation
FR2558467B2 (fr) * 1981-10-23 1987-03-20 Roussel Uclaf Nouveau produit derive de l'acide 3-amino 2-oxo azetidine 1-sulfamique, son procede de preparation, son application comme medicament et un produit intermediaire necessaire a sa preparation
JPS6036458A (ja) * 1983-08-08 1985-02-25 Sumitomo Chem Co Ltd β−ラクタム誘導体の製造法
FR2559486B1 (fr) * 1984-02-13 1988-02-12 Roussel Uclaf Nouveaux derives de l'acide 1-dethia 2-thia cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2586020B2 (fr) * 1985-08-09 1988-10-14 Roussel Uclaf Nouveaux derives de l'acide 1-dethia 2-thia cephalosporanique, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant
FR2588867B1 (fr) * 1985-10-23 1988-12-09 Roussel Uclaf Nouveaux produits derives de la serie de la 3-amino 2-oxo azetidine, leur procede de preparation et leur application
FR2610630B2 (fr) * 1987-02-06 1989-05-26 Roussel Uclaf Nouveaux derives de l'acide 1-dethia 2-thia cephalosporanique, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2046823A1 (de) * 1970-09-23 1972-03-30 Farbwerke Hoechst AG vormals Meister Lucius & Brüning, 6000 Frankfurt Neue Azetidinone-(2) und Verfahren zu deren Herstellung

Also Published As

Publication number Publication date
FR2313362A1 (fr) 1976-12-31
ES460722A1 (es) 1978-05-01
GB1553430A (en) 1979-09-26
CH627475A5 (en) 1982-01-15
FR2324639A1 (fr) 1977-04-15
IE43845L (en) 1976-11-05
AU500636B2 (en) 1979-05-31
ES460746A1 (es) 1978-10-01
NL7604797A (nl) 1976-11-09
JPS51136694A (en) 1976-11-26
ES447577A1 (es) 1977-12-01
AU1366976A (en) 1977-11-10
CH623331A5 (en) 1981-05-29
IE43845B1 (en) 1981-06-17
FR2313362B1 (es) 1979-03-23
LU74873A1 (es) 1977-01-12
FR2324639B1 (es) 1978-11-03
DE2619458A1 (de) 1976-11-18
DK194776A (da) 1976-11-06
CH624670A5 (en) 1981-08-14

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee