JPS55139388A - Cephalosporin derivative - Google Patents
Cephalosporin derivativeInfo
- Publication number
- JPS55139388A JPS55139388A JP4429279A JP4429279A JPS55139388A JP S55139388 A JPS55139388 A JP S55139388A JP 4429279 A JP4429279 A JP 4429279A JP 4429279 A JP4429279 A JP 4429279A JP S55139388 A JPS55139388 A JP S55139388A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- acetoxyl
- nitrile
- reaction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
Abstract
NEW MATERIAL:Compounds of formula I (R1 is nitrile, when R2 is acetoxyl; when R1 is group of formula IV, R2 is one of formula V; R3 is 1W4C lower alkyl).
EXAMPLE: The compound of formula I where R1 is nitrile, R2 is acetoxyl and R3 is ethyl.
USE: Antibiotics effective on gram-positive and -negative bacteria.
PREPARATION: The reaction of a compound of formula II(M+ is Li+, K+) with 4-(6-guanidino)hexonoyloxybenzoic alkyl ester methanesulfonate salt is conducted in a solvent such as water to give the compound of formula I where usually cooling or heating is preferred during the reaction.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4429279A JPS55139388A (en) | 1979-04-13 | 1979-04-13 | Cephalosporin derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4429279A JPS55139388A (en) | 1979-04-13 | 1979-04-13 | Cephalosporin derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS55139388A true JPS55139388A (en) | 1980-10-31 |
Family
ID=12687425
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP4429279A Pending JPS55139388A (en) | 1979-04-13 | 1979-04-13 | Cephalosporin derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS55139388A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008142397A1 (en) * | 2007-05-17 | 2008-11-27 | Serentis Limited | Serine protease inhibitors for use in the treatment of bacterial infections |
-
1979
- 1979-04-13 JP JP4429279A patent/JPS55139388A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008142397A1 (en) * | 2007-05-17 | 2008-11-27 | Serentis Limited | Serine protease inhibitors for use in the treatment of bacterial infections |
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