JPS55139388A - Cephalosporin derivative - Google Patents

Cephalosporin derivative

Info

Publication number
JPS55139388A
JPS55139388A JP4429279A JP4429279A JPS55139388A JP S55139388 A JPS55139388 A JP S55139388A JP 4429279 A JP4429279 A JP 4429279A JP 4429279 A JP4429279 A JP 4429279A JP S55139388 A JPS55139388 A JP S55139388A
Authority
JP
Japan
Prior art keywords
formula
compound
acetoxyl
nitrile
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP4429279A
Other languages
Japanese (ja)
Inventor
Tetsuji Kametani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SENDAI FUKUSOKAN KAGAKU KENKYU
SENDAI FUKUSOKAN KAGAKU KENKYUSHO
Original Assignee
SENDAI FUKUSOKAN KAGAKU KENKYU
SENDAI FUKUSOKAN KAGAKU KENKYUSHO
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SENDAI FUKUSOKAN KAGAKU KENKYU, SENDAI FUKUSOKAN KAGAKU KENKYUSHO filed Critical SENDAI FUKUSOKAN KAGAKU KENKYU
Priority to JP4429279A priority Critical patent/JPS55139388A/en
Publication of JPS55139388A publication Critical patent/JPS55139388A/en
Pending legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

NEW MATERIAL:Compounds of formula I (R1 is nitrile, when R2 is acetoxyl; when R1 is group of formula IV, R2 is one of formula V; R3 is 1W4C lower alkyl).
EXAMPLE: The compound of formula I where R1 is nitrile, R2 is acetoxyl and R3 is ethyl.
USE: Antibiotics effective on gram-positive and -negative bacteria.
PREPARATION: The reaction of a compound of formula II(M+ is Li+, K+) with 4-(6-guanidino)hexonoyloxybenzoic alkyl ester methanesulfonate salt is conducted in a solvent such as water to give the compound of formula I where usually cooling or heating is preferred during the reaction.
COPYRIGHT: (C)1980,JPO&Japio
JP4429279A 1979-04-13 1979-04-13 Cephalosporin derivative Pending JPS55139388A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP4429279A JPS55139388A (en) 1979-04-13 1979-04-13 Cephalosporin derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4429279A JPS55139388A (en) 1979-04-13 1979-04-13 Cephalosporin derivative

Publications (1)

Publication Number Publication Date
JPS55139388A true JPS55139388A (en) 1980-10-31

Family

ID=12687425

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4429279A Pending JPS55139388A (en) 1979-04-13 1979-04-13 Cephalosporin derivative

Country Status (1)

Country Link
JP (1) JPS55139388A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008142397A1 (en) * 2007-05-17 2008-11-27 Serentis Limited Serine protease inhibitors for use in the treatment of bacterial infections

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008142397A1 (en) * 2007-05-17 2008-11-27 Serentis Limited Serine protease inhibitors for use in the treatment of bacterial infections

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