JPS5484592A - Isoxazolone carboxylic acid derivatine - Google Patents
Isoxazolone carboxylic acid derivatineInfo
- Publication number
- JPS5484592A JPS5484592A JP15256577A JP15256577A JPS5484592A JP S5484592 A JPS5484592 A JP S5484592A JP 15256577 A JP15256577 A JP 15256577A JP 15256577 A JP15256577 A JP 15256577A JP S5484592 A JPS5484592 A JP S5484592A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- isoxazolone
- derivatine
- carboxylic acid
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A compound of formula I: (R1, R2 and R3 are H, alkyl, or aralkyl groups) and its salt.
EXAMPLE: D-α-(2,3-Dimethyl-5-isoxazolone-4-carboxylamide) benzylpenicillin.
USE: Antibacterials effective against Gram-positive and Gram-negative bacteria, panticularly bacillus pyocyaneus, having a wide antibacterial spectrum.
PROCESS: An α-aminopenicillin of formula II is condensed with a reactive derivative, e.g. an acid halide, a mixed acid anhydride, active amide, etc., in a proper solvent under cooling or room temperature to give the compound of formula I.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15256577A JPS5484592A (en) | 1977-12-19 | 1977-12-19 | Isoxazolone carboxylic acid derivatine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15256577A JPS5484592A (en) | 1977-12-19 | 1977-12-19 | Isoxazolone carboxylic acid derivatine |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5484592A true JPS5484592A (en) | 1979-07-05 |
Family
ID=15543253
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP15256577A Pending JPS5484592A (en) | 1977-12-19 | 1977-12-19 | Isoxazolone carboxylic acid derivatine |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5484592A (en) |
-
1977
- 1977-12-19 JP JP15256577A patent/JPS5484592A/en active Pending
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