FR2324639A1 - Composes analogues aux cephalosporines, leurs intermediaires et procedes pour les preparer - Google Patents

Composes analogues aux cephalosporines, leurs intermediaires et procedes pour les preparer

Info

Publication number
FR2324639A1
FR2324639A1 FR7613251A FR7613251A FR2324639A1 FR 2324639 A1 FR2324639 A1 FR 2324639A1 FR 7613251 A FR7613251 A FR 7613251A FR 7613251 A FR7613251 A FR 7613251A FR 2324639 A1 FR2324639 A1 FR 2324639A1
Authority
FR
France
Prior art keywords
intermediaries
cephalosporins
preparing
methods
analogue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7613251A
Other languages
English (en)
Other versions
FR2324639B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline LLC
Original Assignee
SmithKline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Corp filed Critical SmithKline Corp
Publication of FR2324639A1 publication Critical patent/FR2324639A1/fr
Application granted granted Critical
Publication of FR2324639B1 publication Critical patent/FR2324639B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/36—One oxygen atom
    • C07D263/38—One oxygen atom attached in position 2
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FR7613251A 1975-05-05 1976-05-04 Composes analogues aux cephalosporines, leurs intermediaires et procedes pour les preparer Granted FR2324639A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57422575A 1975-05-05 1975-05-05
US62668675A 1975-10-29 1975-10-29

Publications (2)

Publication Number Publication Date
FR2324639A1 true FR2324639A1 (fr) 1977-04-15
FR2324639B1 FR2324639B1 (fr) 1978-11-03

Family

ID=27076332

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7613251A Granted FR2324639A1 (fr) 1975-05-05 1976-05-04 Composes analogues aux cephalosporines, leurs intermediaires et procedes pour les preparer
FR7628304A Granted FR2313362A1 (fr) 1975-05-05 1976-09-21 Nouvelles 4-oxoazetidines

Family Applications After (1)

Application Number Title Priority Date Filing Date
FR7628304A Granted FR2313362A1 (fr) 1975-05-05 1976-09-21 Nouvelles 4-oxoazetidines

Country Status (11)

Country Link
JP (1) JPS51136694A (fr)
AU (1) AU500636B2 (fr)
CH (3) CH623331A5 (fr)
DE (1) DE2619458A1 (fr)
DK (1) DK194776A (fr)
ES (3) ES447577A1 (fr)
FR (2) FR2324639A1 (fr)
GB (2) GB1553430A (fr)
IE (1) IE43845B1 (fr)
LU (1) LU74873A1 (fr)
NL (1) NL7604797A (fr)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0000645A1 (fr) * 1977-07-26 1979-02-07 Smithkline Beckman Corporation Isopénicillines, procédés pour leur préparation et compositions qui les contiennent
FR2505840A1 (fr) * 1981-05-13 1982-11-19 Roussel Uclaf Nouveaux produits derives de l'acide 2-amino thiazolyl 2-oxyimino acetamido bicyclo-octene carboxylique, leur procede de preparation et leur application comme medicaments
FR2552089A2 (fr) * 1981-05-13 1985-03-22 Roussel Uclaf Nouveaux produits derives de l'acide 2-amino thiazolyl 2-oxyimino acetamido bicyclo-octene carboxylique, leur procede de preparation et leur application comme medicaments
FR2559486A1 (fr) * 1984-02-13 1985-08-16 Roussel Uclaf Nouveaux derives de l'acide 1-dethia 2-thia cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2586020A2 (fr) * 1985-08-09 1987-02-13 Roussel Uclaf Nouveaux derives de l'acide 1-dethia 2-thia cephalosporanique, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant
FR2610630A2 (fr) * 1987-02-06 1988-08-12 Roussel Uclaf Nouveaux derives de l'acide 1-dethia 2-thia cephalosporanique, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1262128A (fr) * 1981-08-27 1989-10-03 Christian N. Hubschwerlen .beta.-lactams
FR2538389B2 (fr) * 1981-10-23 1986-05-16 Roussel Uclaf Nouveaux produits derives de l'acide 3-amino 2-oxo azetidine-1-sulfamique, nouveau procede de preparation de produits optiquement actifs, application des nouveaux produits comme medicaments et produits necessaires a leur preparation
FR2515182B1 (fr) * 1981-10-23 1986-05-09 Roussel Uclaf Nouveaux produits derives de l'acide 3-amino 2-oxo azetidine 1-sulfamique, leur procede de preparation, leur application comme medicaments et les produits intermediaires necessaires a leur preparation
FR2558467B2 (fr) * 1981-10-23 1987-03-20 Roussel Uclaf Nouveau produit derive de l'acide 3-amino 2-oxo azetidine 1-sulfamique, son procede de preparation, son application comme medicament et un produit intermediaire necessaire a sa preparation
JPS6036458A (ja) * 1983-08-08 1985-02-25 Sumitomo Chem Co Ltd β−ラクタム誘導体の製造法
FR2588867B1 (fr) * 1985-10-23 1988-12-09 Roussel Uclaf Nouveaux produits derives de la serie de la 3-amino 2-oxo azetidine, leur procede de preparation et leur application

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2046823A1 (de) * 1970-09-23 1972-03-30 Farbwerke Hoechst AG vormals Meister Lucius & Brüning, 6000 Frankfurt Neue Azetidinone-(2) und Verfahren zu deren Herstellung

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NEANT *

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0000645A1 (fr) * 1977-07-26 1979-02-07 Smithkline Beckman Corporation Isopénicillines, procédés pour leur préparation et compositions qui les contiennent
FR2505840A1 (fr) * 1981-05-13 1982-11-19 Roussel Uclaf Nouveaux produits derives de l'acide 2-amino thiazolyl 2-oxyimino acetamido bicyclo-octene carboxylique, leur procede de preparation et leur application comme medicaments
US4476124A (en) * 1981-05-13 1984-10-09 Roussel Uclaf 2-Amino-4-thiazolyl-2-oxyimino-acetamido-bicyclooctene-carboxylic acids
FR2552089A2 (fr) * 1981-05-13 1985-03-22 Roussel Uclaf Nouveaux produits derives de l'acide 2-amino thiazolyl 2-oxyimino acetamido bicyclo-octene carboxylique, leur procede de preparation et leur application comme medicaments
EP0153229A3 (en) * 1984-02-13 1985-10-09 Roussel-Uclaf 1-dethia 2-thia-cephalosporanic acid derivatives, process and intermediates for their preparation, their use as therapeutic agents and the compositions containing them
EP0153229A2 (fr) * 1984-02-13 1985-08-28 Roussel-Uclaf Nouveaux dérivés de l'acide 1-déthia 2-thia céphalosporanique, leur procédé et leurs intermédiaires de préparation, leur application comme médicaments et les compositions les renfermant
FR2559486A1 (fr) * 1984-02-13 1985-08-16 Roussel Uclaf Nouveaux derives de l'acide 1-dethia 2-thia cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2586019A2 (fr) * 1984-02-13 1987-02-13 Roussel Uclaf Nouveaux derives de l'acide 1-dethia 2-thia cephalosporanique, leur application comme medicaments et les compositions pharmaceutiques les renfermant
FR2610628A2 (fr) * 1984-02-13 1988-08-12 Roussel Uclaf Nouveaux derives de l'acide 1-dethia 2-thia cephalosporanique, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant
FR2610629A2 (fr) * 1984-02-13 1988-08-12 Roussel Uclaf Nouveaux derives de l'acide 1-dethia 2-thia cephalosporanique, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant
FR2586020A2 (fr) * 1985-08-09 1987-02-13 Roussel Uclaf Nouveaux derives de l'acide 1-dethia 2-thia cephalosporanique, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant
EP0214029A1 (fr) * 1985-08-09 1987-03-11 Roussel-Uclaf Dérivés de l'acide l-déthia 2-thia céphalosporanique, leur procédé de préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant
FR2610630A2 (fr) * 1987-02-06 1988-08-12 Roussel Uclaf Nouveaux derives de l'acide 1-dethia 2-thia cephalosporanique, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant
EP0282365A1 (fr) * 1987-02-06 1988-09-14 Roussel-Uclaf Dérivés de l'acide l-déthia 2-thia céphalosporanique, leur procédé de préparation, leur application comme médicaments et les compositions pharmaceutiques les contenant

Also Published As

Publication number Publication date
CH624670A5 (en) 1981-08-14
FR2313362B1 (fr) 1979-03-23
AU500636B2 (en) 1979-05-31
DE2619458A1 (de) 1976-11-18
CH623331A5 (en) 1981-05-29
JPS51136694A (en) 1976-11-26
GB1553429A (en) 1979-09-26
ES460722A1 (es) 1978-05-01
AU1366976A (en) 1977-11-10
CH627475A5 (en) 1982-01-15
IE43845B1 (en) 1981-06-17
DK194776A (da) 1976-11-06
IE43845L (en) 1976-11-05
NL7604797A (nl) 1976-11-09
ES460746A1 (es) 1978-10-01
GB1553430A (en) 1979-09-26
FR2324639B1 (fr) 1978-11-03
FR2313362A1 (fr) 1976-12-31
LU74873A1 (fr) 1977-01-12
ES447577A1 (es) 1977-12-01

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Legal Events

Date Code Title Description
ST Notification of lapse