GB1511390A - Imidazolylalkyl sulphide antifungal agents - Google Patents
Imidazolylalkyl sulphide antifungal agentsInfo
- Publication number
- GB1511390A GB1511390A GB49797/75A GB4979775A GB1511390A GB 1511390 A GB1511390 A GB 1511390A GB 49797/75 A GB49797/75 A GB 49797/75A GB 4979775 A GB4979775 A GB 4979775A GB 1511390 A GB1511390 A GB 1511390A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- atom
- alkyl
- imidazolylalkyl
- sulphide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- UCKMPCXJQFINFW-UHFFFAOYSA-N Sulphide Chemical compound [S-2] UCKMPCXJQFINFW-UHFFFAOYSA-N 0.000 title 1
- 229940121375 antifungal agent Drugs 0.000 title 1
- 239000003429 antifungal agent Substances 0.000 title 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000010561 standard procedure Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Priority Applications (34)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB49797/75A GB1511390A (en) | 1975-12-04 | 1975-12-04 | Imidazolylalkyl sulphide antifungal agents |
| AR265558A AR223634A1 (es) | 1975-12-04 | 1976-01-22 | Un procedimiento para preparar sulfuros de 1-aril-2-(1-imidazolil)-alquilo que poseen actividad antifungica |
| ZA766280A ZA766280B (en) | 1975-12-04 | 1976-10-21 | Antifungal agents |
| NZ182565A NZ182565A (en) | 1975-12-04 | 1976-11-08 | 1-aryl-2-(1-imidazolyl)-alkyl sulphides and fungicidal compositions |
| IL50869A IL50869A (en) | 1975-12-04 | 1976-11-09 | Heterocyclylthio-ethylimidazole derivatives,their preparation and pharmaceutical compositions containing them |
| PH19125A PH14175A (en) | 1975-12-04 | 1976-11-15 | Imidazole derivative and pharmaceutical composition thereof |
| AU19688/76A AU504085B2 (en) | 1975-12-04 | 1976-11-16 | Imidazole derivatves |
| YU2816/76A YU40157B (en) | 1975-12-04 | 1976-11-18 | Process for obtaining new imidazole derivatives |
| EG722/76A EG12483A (en) | 1975-12-04 | 1976-11-21 | Process for preparing of novel imidazole derivatives used as fungicides |
| JP51140604A JPS5277062A (en) | 1975-12-04 | 1976-11-22 | Novel imidazole derivatives and composition thereof |
| CA266,272A CA1056380A (en) | 1975-12-04 | 1976-11-22 | Process for preparation of novel imidazole derivatives |
| US05/745,305 US4107314A (en) | 1975-12-04 | 1976-11-26 | Antifungal thio-alkyl-imidazole derivatives |
| RO7688592A RO72349A (ro) | 1975-12-04 | 1976-11-30 | Procedeu de preparare a unor derivati de imidazol cu actiune farmacologica |
| PT65904A PT65904B (fr) | 1975-12-04 | 1976-11-30 | Procede analogique pour preparer agents anti-fungo |
| CS767763A CS195744B2 (en) | 1975-12-04 | 1976-11-30 | Method of producing new derivatives of imidazole |
| AT889476A AT354435B (de) | 1975-12-04 | 1976-12-01 | Verfahren zur herstellung von neuen 1-aryl-2-(1 -imidazolyl)-alkylsulfiden, von deren saeure- additionssalzen und optisch aktiven ver- bindungen |
| ES453867A ES453867A1 (es) | 1975-12-04 | 1976-12-02 | Procedimiento para preparar derivados de imidazol. |
| HU76PI554A HU177882B (en) | 1975-12-04 | 1976-12-02 | Process for preparing new imidazolyl-alkyl-sulphides |
| NL7613425.A NL165463C (nl) | 1975-12-04 | 1976-12-02 | Werkwijze voor de bereiding van fungicide imidazolyl- -derivaten en voor de bereiding van preparaten die ze bevatten. |
| GR52301A GR61774B (en) | 1975-12-04 | 1976-12-02 | Preparation process of antifungal agents |
| FI763471A FI62300C (fi) | 1975-12-04 | 1976-12-02 | Foerfarande foer framstaellning av terapeutiskt anvaendbara 1-ryl-2-(1-imidazolyl)-etylsulfidderivat |
| BE172928A BE849012A (fr) | 1975-12-04 | 1976-12-02 | Nouveaux derives imidazoliques, leur procede de preparation et composition pharmaceutique les contenant |
| SU762426153A SU635871A3 (ru) | 1975-12-04 | 1976-12-02 | Способ получени производных имидазола или их солей |
| DE2654665A DE2654665C3 (de) | 1975-12-04 | 1976-12-02 | 1-Aryl-2-(1-imidazolyl)-alkylsulfide, Verfahren zu ihrer Herstellung und diese enthaltende Antimycotica |
| IE2655/76A IE44105B1 (en) | 1975-12-04 | 1976-12-03 | Imidazolyl-alkyl sulphide antifungal agents |
| LU76326A LU76326A1 (enExample) | 1975-12-04 | 1976-12-03 | |
| CH1526776A CH599163A5 (enExample) | 1975-12-04 | 1976-12-03 | |
| SE7613615A SE423544C (sv) | 1975-12-04 | 1976-12-03 | Analogiförfarande för framställning av imidazolderivat med antifungisk aktivitet |
| DK545076A DK545076A (da) | 1975-12-04 | 1976-12-03 | Fremgangsmade til fremstilling af imidazolderivater |
| BG034825A BG28261A3 (en) | 1975-12-04 | 1976-12-03 | Method of obtaining of imidazol derivatives |
| DD196105A DD127186A5 (enExample) | 1975-12-04 | 1976-12-03 | |
| FR7636611A FR2333506A1 (fr) | 1975-12-04 | 1976-12-03 | Nouveaux derives imidazoliques, leur procede de preparation et composition pharmaceutique les contenant |
| NO764134A NO145791C (no) | 1975-12-04 | 1976-12-03 | Analogifremgangsmaate ved fremstilling av nye terapeutisk aktive imidazolderivater |
| PL1976194143A PL104366B1 (pl) | 1975-12-04 | 1976-12-03 | Sposob wytwarzania nowych pochodnych imidazolu |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB49797/75A GB1511390A (en) | 1975-12-04 | 1975-12-04 | Imidazolylalkyl sulphide antifungal agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1511390A true GB1511390A (en) | 1978-05-17 |
Family
ID=10453567
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB49797/75A Expired GB1511390A (en) | 1975-12-04 | 1975-12-04 | Imidazolylalkyl sulphide antifungal agents |
Country Status (34)
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4307105A (en) | 1979-07-05 | 1981-12-22 | E. R. Squibb & Sons, Inc. | Imidazolylethoxymethyl derivatives of thiazole |
| EP0066993A1 (en) * | 1981-06-09 | 1982-12-15 | Imperial Chemical Industries Plc | Quinoline derivatives |
| EP0124208A1 (en) * | 1983-03-29 | 1984-11-07 | Imperial Chemical Industries Plc | Quinoline derivatives |
| GB2161160B (en) * | 1984-07-06 | 1989-05-24 | Fisons Plc | Heterocyclic sulphinyl compounds |
| DE3816201A1 (de) * | 1988-04-29 | 1989-11-23 | Lentia Gmbh | Neue 2-aryl-2-(2-pyridylthio)-1-(1h-1,2,4-triazolyl)-ethane, verfahren zu ihrer herstellung und verwendung als fungizide |
| WO2003001913A1 (de) * | 2001-06-26 | 2003-01-09 | Bayer Chemicals Ag | Thiazine und thiazole als materialschutzmittel |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0001654B1 (de) * | 1977-10-13 | 1981-07-22 | Siegfried Aktiengesellschaft | Imidazolyläthyl-oxyalkoxy-Derivate und ihre Thio-Analoge, pharmazeutische Zubereitungen mit diesen Stoffen und Verfahren zu ihrer Herstellung |
| DE2756269A1 (de) * | 1977-12-16 | 1979-06-21 | Bayer Ag | Azolylalkyl-pyridinyl-aether, verfahren zu ihrer herstellung sowie ihre verwendung als fungizide |
| US4343805A (en) * | 1978-12-16 | 1982-08-10 | John Wyeth & Brother Limited | Heterocyclic compounds |
| US4272545A (en) * | 1979-02-02 | 1981-06-09 | Syntex (U.S.A.) Inc. | Derivatives of thienyl- and furyl-substituted N-butyl and N-phenyl imidazoles |
| US4248881A (en) * | 1979-12-20 | 1981-02-03 | E. R. Squibb & Sons, Inc. | Imidazolylethoxymethyl derivatives of pyrazole |
| CA1155853A (en) * | 1980-06-06 | 1983-10-25 | Joseph A. Martin | Imidazole derivatives and preparation thereof |
| US4458079A (en) * | 1980-08-08 | 1984-07-03 | Bristol-Myers Company | Sulfur-containing imidazoles |
| US4661602A (en) * | 1985-03-29 | 1987-04-28 | G. D. Searle & Co. | Substituted alkyl imidazole derivatives |
| US4628104A (en) * | 1985-04-08 | 1986-12-09 | G. D. Searle & Co. | Imidazole ketone derivatives |
| US4761483A (en) * | 1985-06-26 | 1988-08-02 | G. D. Searle & Co. | Chloro-substituted ketone imidazole derivatives |
| US6545163B1 (en) * | 1995-10-02 | 2003-04-08 | Napp Technologies | Process to prepare 1-aryl-2-(1-imidazolyl) alkyl ethers and thioethers |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU557755A3 (ru) * | 1968-08-19 | 1977-05-05 | Янссен Фармасьютика Н.В. (Фирма) | Способ получени производных имидазола |
| GB1475271A (en) * | 1975-04-30 | 1977-06-01 | Pfizer Ltd | 1-aryl-2-1-imidazolyl-alkyl ethers and thioethers and their use as antifungal agents |
-
1975
- 1975-12-04 GB GB49797/75A patent/GB1511390A/en not_active Expired
-
1976
- 1976-01-22 AR AR265558A patent/AR223634A1/es active
- 1976-10-21 ZA ZA766280A patent/ZA766280B/xx unknown
- 1976-11-08 NZ NZ182565A patent/NZ182565A/xx unknown
- 1976-11-09 IL IL50869A patent/IL50869A/xx unknown
- 1976-11-15 PH PH19125A patent/PH14175A/en unknown
- 1976-11-16 AU AU19688/76A patent/AU504085B2/en not_active Expired
- 1976-11-18 YU YU2816/76A patent/YU40157B/xx unknown
- 1976-11-21 EG EG722/76A patent/EG12483A/xx active
- 1976-11-22 CA CA266,272A patent/CA1056380A/en not_active Expired
- 1976-11-22 JP JP51140604A patent/JPS5277062A/ja active Granted
- 1976-11-26 US US05/745,305 patent/US4107314A/en not_active Expired - Lifetime
- 1976-11-30 RO RO7688592A patent/RO72349A/ro unknown
- 1976-11-30 CS CS767763A patent/CS195744B2/cs unknown
- 1976-11-30 PT PT65904A patent/PT65904B/pt unknown
- 1976-12-01 AT AT889476A patent/AT354435B/de not_active IP Right Cessation
- 1976-12-02 SU SU762426153A patent/SU635871A3/ru active
- 1976-12-02 HU HU76PI554A patent/HU177882B/hu unknown
- 1976-12-02 DE DE2654665A patent/DE2654665C3/de not_active Expired
- 1976-12-02 NL NL7613425.A patent/NL165463C/xx not_active IP Right Cessation
- 1976-12-02 GR GR52301A patent/GR61774B/el unknown
- 1976-12-02 ES ES453867A patent/ES453867A1/es not_active Expired
- 1976-12-02 BE BE172928A patent/BE849012A/xx not_active IP Right Cessation
- 1976-12-02 FI FI763471A patent/FI62300C/fi not_active IP Right Cessation
- 1976-12-03 LU LU76326A patent/LU76326A1/xx unknown
- 1976-12-03 PL PL1976194143A patent/PL104366B1/pl unknown
- 1976-12-03 IE IE2655/76A patent/IE44105B1/en unknown
- 1976-12-03 DK DK545076A patent/DK545076A/da not_active Application Discontinuation
- 1976-12-03 DD DD196105A patent/DD127186A5/xx unknown
- 1976-12-03 FR FR7636611A patent/FR2333506A1/fr active Granted
- 1976-12-03 SE SE7613615A patent/SE423544C/xx unknown
- 1976-12-03 NO NO764134A patent/NO145791C/no unknown
- 1976-12-03 CH CH1526776A patent/CH599163A5/xx not_active IP Right Cessation
- 1976-12-03 BG BG034825A patent/BG28261A3/xx unknown
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4307105A (en) | 1979-07-05 | 1981-12-22 | E. R. Squibb & Sons, Inc. | Imidazolylethoxymethyl derivatives of thiazole |
| EP0066993A1 (en) * | 1981-06-09 | 1982-12-15 | Imperial Chemical Industries Plc | Quinoline derivatives |
| EP0124208A1 (en) * | 1983-03-29 | 1984-11-07 | Imperial Chemical Industries Plc | Quinoline derivatives |
| GB2161160B (en) * | 1984-07-06 | 1989-05-24 | Fisons Plc | Heterocyclic sulphinyl compounds |
| DE3816201A1 (de) * | 1988-04-29 | 1989-11-23 | Lentia Gmbh | Neue 2-aryl-2-(2-pyridylthio)-1-(1h-1,2,4-triazolyl)-ethane, verfahren zu ihrer herstellung und verwendung als fungizide |
| WO2003001913A1 (de) * | 2001-06-26 | 2003-01-09 | Bayer Chemicals Ag | Thiazine und thiazole als materialschutzmittel |
| US7084137B2 (en) | 2001-06-26 | 2006-08-01 | Bayer Aktiengesellschaft | Thiazines and thiazoles as agents for protecting materials |
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |