GB1500105A - Substituted benzamides their preparation and compositions containing them - Google Patents
Substituted benzamides their preparation and compositions containing themInfo
- Publication number
- GB1500105A GB1500105A GB23695/76A GB2369576A GB1500105A GB 1500105 A GB1500105 A GB 1500105A GB 23695/76 A GB23695/76 A GB 23695/76A GB 2369576 A GB2369576 A GB 2369576A GB 1500105 A GB1500105 A GB 1500105A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- alkyl
- alkoxy
- hydrogen
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940054066 benzamide antipsychotics Drugs 0.000 title abstract 2
- 150000003936 benzamides Chemical class 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000006556 (C1-C5) alkylsulphonyl group Chemical group 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000003302 alkenyloxy group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 230000003474 anti-emetic effect Effects 0.000 abstract 1
- 235000010233 benzoic acid Nutrition 0.000 abstract 1
- 150000001559 benzoic acids Chemical class 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7518001A FR2313935A1 (fr) | 1975-06-10 | 1975-06-10 | Nouveaux benzamides substitues, leurs derives et leur procede de preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1500105A true GB1500105A (en) | 1978-02-08 |
Family
ID=9156239
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB23695/76A Expired GB1500105A (en) | 1975-06-10 | 1976-06-08 | Substituted benzamides their preparation and compositions containing them |
Country Status (37)
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3523076A1 (de) * | 1984-06-28 | 1986-01-09 | Bristol-Myers Co., New York, N.Y. | Substituierte benzamide, verfahren zu deren herstellung und diese verbindungen enthaltende pharmazeutische mittel |
| US4820715A (en) * | 1984-06-28 | 1989-04-11 | Bristol-Myers Company | Anti-emetic quinuclidinyl benzamides |
| US5011992A (en) * | 1984-06-28 | 1991-04-30 | Bristol-Myers Squibb Company | Pharmacologically active substituted benzamides |
| EP0499995A3 (en) * | 1991-02-20 | 1992-09-23 | Nisshin Flour Milling Co., Ltd. | Piperidine derivatives |
| RU2205009C1 (ru) * | 2002-03-27 | 2003-05-27 | Государственный научный центр - Институт биофизики | Противорвотное средство бензамид |
| US9375486B2 (en) | 2012-09-17 | 2016-06-28 | Nektar Therapeutics | Oligomer-containing benzamide-based compounds |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ186175A (en) * | 1977-01-27 | 1980-03-05 | Shionogi & Co | Meta-sulphonamidobenzamide derivatives |
| FR2415099A1 (fr) * | 1978-01-20 | 1979-08-17 | Ile De France | Nouveaux derives de 4-amino-5-alkylsulfonyl ortho-anisamides, leurs procedes de preparation et leur application comme psychotropes |
| FR2438650A1 (fr) * | 1978-10-11 | 1980-05-09 | Ile De France | N-(1-methyl 2-pyrrolidinyl methyl) 2,3-dimethoxy 5-methylsulfamoyl benzamide et ses derives, leurs methodes de preparation et leur application dans le traitement des troubles du bas appareil urinaire |
| JPS597160A (ja) * | 1982-06-28 | 1984-01-14 | ラボラトリーオス・デラグランヘ・エセ・ア | Ｎ−（１−プロピル−２−ピロリジニルメチル）−２−メトキシ−５−スルフアモイルベンズアミド、その製造方法およびこれを有効成分とする抗うつ剤 |
-
1975
- 1975-06-10 FR FR7518001A patent/FR2313935A1/fr active Granted
-
1976
- 1976-05-21 ZA ZA763042A patent/ZA763042B/xx unknown
- 1976-05-21 BE BE1007404A patent/BE842059A/xx not_active IP Right Cessation
- 1976-05-22 RO RO7686179A patent/RO70265A/ro unknown
- 1976-05-22 DE DE19762623075 patent/DE2623075A1/de not_active Withdrawn
- 1976-05-24 AR AR263374A patent/AR210888A1/es active
- 1976-05-27 IN IN926/CAL/1976A patent/IN142899B/en unknown
- 1976-05-27 AU AU14360/76A patent/AU506001B2/en not_active Expired
- 1976-05-28 YU YU1318/76A patent/YU39352B/xx unknown
- 1976-06-01 AT AT400176A patent/AT358571B/de not_active IP Right Cessation
- 1976-06-01 IE IE1166/76A patent/IE43375B1/en unknown
- 1976-06-01 PT PT65164A patent/PT65164B/pt unknown
- 1976-06-02 EG EG326/76A patent/EG12285A/xx active
- 1976-06-03 ZM ZM65/76A patent/ZM6576A1/xx unknown
- 1976-06-04 NZ NZ181072A patent/NZ181072A/xx unknown
- 1976-06-04 CS CS763724A patent/CS189007B2/cs unknown
- 1976-06-04 BG BG033362A patent/BG27360A3/xx unknown
- 1976-06-07 SU SU762362660A patent/SU607551A3/ru active
- 1976-06-07 PH PH18542A patent/PH13912A/en unknown
- 1976-06-08 LU LU75104A patent/LU75104A1/xx unknown
- 1976-06-08 GB GB23695/76A patent/GB1500105A/en not_active Expired
- 1976-06-08 ES ES448643A patent/ES448643A1/es not_active Expired
- 1976-06-08 DD DD193235A patent/DD124380A5/xx not_active IP Right Cessation
- 1976-06-08 JP JP51067553A patent/JPS6055503B2/ja not_active Expired
- 1976-06-08 SE SE7606424A patent/SE415971B/xx not_active IP Right Cessation
- 1976-06-09 MX MX76291U patent/MX3580E/es unknown
- 1976-06-09 DK DK255276A patent/DK255276A/da unknown
- 1976-06-09 PL PL1976190247A patent/PL103075B1/pl not_active IP Right Cessation
- 1976-06-09 HU HU76SO00001171A patent/HU172195B/hu unknown
- 1976-06-09 SU SU762366253A patent/SU645557A3/ru active
- 1976-06-09 NO NO761977A patent/NO146058C/no unknown
- 1976-06-09 CA CA254,480A patent/CA1064930A/en not_active Expired
- 1976-06-09 OA OA55847A patent/OA05350A/xx unknown
- 1976-06-10 PL PL1976190304A patent/PL102929B1/pl unknown
- 1976-06-10 MW MW16/76A patent/MW1676A1/xx unknown
- 1976-06-10 FI FI761669A patent/FI761669A7/fi not_active Application Discontinuation
- 1976-06-10 NL NLAANVRAGE7606284,A patent/NL186382C/xx not_active IP Right Cessation
- 1976-06-10 CH CH736076A patent/CH596175A5/xx not_active IP Right Cessation
-
1979
- 1979-07-12 HK HK469/79A patent/HK46979A/xx unknown
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3523076A1 (de) * | 1984-06-28 | 1986-01-09 | Bristol-Myers Co., New York, N.Y. | Substituierte benzamide, verfahren zu deren herstellung und diese verbindungen enthaltende pharmazeutische mittel |
| US4820715A (en) * | 1984-06-28 | 1989-04-11 | Bristol-Myers Company | Anti-emetic quinuclidinyl benzamides |
| US5011992A (en) * | 1984-06-28 | 1991-04-30 | Bristol-Myers Squibb Company | Pharmacologically active substituted benzamides |
| AT399338B (de) * | 1987-05-18 | 1995-04-25 | Bristol Myers Squibb Co | Neue substituierte benzamide, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen, die diese benzamide enthalten |
| EP0499995A3 (en) * | 1991-02-20 | 1992-09-23 | Nisshin Flour Milling Co., Ltd. | Piperidine derivatives |
| US5246945A (en) * | 1991-02-20 | 1993-09-21 | Nisshin Flour Milling Co., Ltd. | Piperidine derivatives |
| RU2205009C1 (ru) * | 2002-03-27 | 2003-05-27 | Государственный научный центр - Институт биофизики | Противорвотное средство бензамид |
| US9375486B2 (en) | 2012-09-17 | 2016-06-28 | Nektar Therapeutics | Oligomer-containing benzamide-based compounds |
| US9937266B2 (en) | 2012-09-17 | 2018-04-10 | Nektar Therapeutics | Oligomer-containing benzamide-based compounds |
| US10434181B2 (en) | 2012-09-17 | 2019-10-08 | Nektar Therapeutics | Oligomer-containing benzamide-based compounds |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 19920608 |