GB1476993A - 27-non-cholesterol derivatives - Google Patents

27-non-cholesterol derivatives

Info

Publication number
GB1476993A
GB1476993A GB4746676A GB4746676A GB1476993A GB 1476993 A GB1476993 A GB 1476993A GB 4746676 A GB4746676 A GB 4746676A GB 4746676 A GB4746676 A GB 4746676A GB 1476993 A GB1476993 A GB 1476993A
Authority
GB
United Kingdom
Prior art keywords
compounds
alkyl
alkoxy
acetoacetoxy
alkanoyloxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4746676A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of GB1476993A publication Critical patent/GB1476993A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J15/00—Stereochemically pure steroids containing carbon, hydrogen, halogen or oxygen having a partially or totally inverted skeleton, e.g. retrosteroids, L-isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB4746676A 1973-06-18 1974-06-17 27-non-cholesterol derivatives Expired GB1476993A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37109173A 1973-06-18 1973-06-18
US00408788A US3856780A (en) 1973-06-18 1973-10-23 Synthesis of 25-hydroxycholesterol and derivatives thereof

Publications (1)

Publication Number Publication Date
GB1476993A true GB1476993A (en) 1977-06-16

Family

ID=27005234

Family Applications (2)

Application Number Title Priority Date Filing Date
GB4746676A Expired GB1476993A (en) 1973-06-18 1974-06-17 27-non-cholesterol derivatives
GB2671874A Expired GB1476992A (en) 1973-06-18 1974-06-17 25-hydroxychlorestrol and derivatives thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB2671874A Expired GB1476992A (en) 1973-06-18 1974-06-17 25-hydroxychlorestrol and derivatives thereof

Country Status (8)

Country Link
US (1) US3856780A (cg-RX-API-DMAC10.html)
JP (1) JPS5614680B2 (cg-RX-API-DMAC10.html)
AT (1) AT340612B (cg-RX-API-DMAC10.html)
CH (1) CH620227A5 (cg-RX-API-DMAC10.html)
DE (1) DE2426528C3 (cg-RX-API-DMAC10.html)
FR (1) FR2233335B1 (cg-RX-API-DMAC10.html)
GB (2) GB1476993A (cg-RX-API-DMAC10.html)
NL (1) NL172066C (cg-RX-API-DMAC10.html)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5371056A (en) * 1976-12-08 1978-06-24 Chugai Pharmaceut Co Ltd Steroid derivs.
US4230625A (en) * 1979-04-12 1980-10-28 Hoffmann-La Roche Inc. Process for chenodeoxycholic acid and intermediates therefore
EP0019059B1 (de) * 1979-05-18 1982-12-29 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Verfahren zur Herstellung von Cholestenderivaten und neue Zwischenprodukte in deren Herstellung
IL60270A0 (en) * 1979-06-14 1980-09-16 Diamond Shamrock Corp Preparation of 25-ydroxycholesterol
JPS61227592A (ja) * 1985-04-01 1986-10-09 Chugai Pharmaceut Co Ltd ２７−ノル−２５−オキソコレステロ−ル類
US5225569A (en) * 1991-08-09 1993-07-06 Hoffmann-La Roche Inc. Process for precursors to calcitriol and related compounds
US5182393A (en) * 1991-08-09 1993-01-26 Hoffmann-La Roche Inc. Process for precursors to calcitriol and related compounds
US5547868A (en) * 1993-06-09 1996-08-20 Regents Of The University Of California Cholesterol disposal fusion enzymes
CA2586679A1 (en) 2004-11-12 2006-05-18 Bioxell Spa Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer
CN115010781B (zh) * 2022-07-15 2022-10-25 中节能万润股份有限公司 一种高纯度胆固醇的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1052283B (it) * 1968-07-01 1981-06-20 Wisconsin Alumni Res Found Processo per preparare composti del calciferolo e relativi composti

Also Published As

Publication number Publication date
NL172066B (nl) 1983-02-01
FR2233335B1 (cg-RX-API-DMAC10.html) 1977-10-07
JPS5614680B2 (cg-RX-API-DMAC10.html) 1981-04-06
NL172066C (nl) 1983-07-01
US3856780A (en) 1974-12-24
JPS5035152A (cg-RX-API-DMAC10.html) 1975-04-03
DE2426528C3 (de) 1981-04-09
DE2426528A1 (de) 1975-01-09
ATA497374A (de) 1977-04-15
FR2233335A1 (cg-RX-API-DMAC10.html) 1975-01-10
NL7408128A (cg-RX-API-DMAC10.html) 1974-12-20
CH620227A5 (cg-RX-API-DMAC10.html) 1980-11-14
AT340612B (de) 1977-12-27
GB1476992A (en) 1977-06-16
DE2426528B2 (de) 1980-06-26

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee