GB1465781A - Pharmaceutical preparations - Google Patents
Pharmaceutical preparationsInfo
- Publication number
- GB1465781A GB1465781A GB692974A GB692974A GB1465781A GB 1465781 A GB1465781 A GB 1465781A GB 692974 A GB692974 A GB 692974A GB 692974 A GB692974 A GB 692974A GB 1465781 A GB1465781 A GB 1465781A
- Authority
- GB
- United Kingdom
- Prior art keywords
- cellulose
- hydrophilising
- particles
- feb
- free
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000825 pharmaceutical preparation Substances 0.000 title abstract 2
- 239000002245 particle Substances 0.000 abstract 3
- 239000013543 active substance Substances 0.000 abstract 2
- 239000000463 material Substances 0.000 abstract 2
- CPJSUEIXXCENMM-UHFFFAOYSA-N phenacetin Chemical compound CCOC1=CC=C(NC(C)=O)C=C1 CPJSUEIXXCENMM-UHFFFAOYSA-N 0.000 abstract 2
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 abstract 1
- 101000653791 Bos taurus Protein S100-A12 Proteins 0.000 abstract 1
- 239000001856 Ethyl cellulose Substances 0.000 abstract 1
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 abstract 1
- 244000165918 Eucalyptus papuana Species 0.000 abstract 1
- 229920000084 Gum arabic Polymers 0.000 abstract 1
- 229920001479 Hydroxyethyl methyl cellulose Polymers 0.000 abstract 1
- 229920002472 Starch Polymers 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 1
- 239000000205 acacia gum Substances 0.000 abstract 1
- 235000010489 acacia gum Nutrition 0.000 abstract 1
- 229960001138 acetylsalicylic acid Drugs 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 229940049706 benzodiazepine Drugs 0.000 abstract 1
- 150000001557 benzodiazepines Chemical class 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 239000001913 cellulose Substances 0.000 abstract 1
- 229920002678 cellulose Polymers 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 229920001249 ethyl cellulose Polymers 0.000 abstract 1
- 235000019325 ethyl cellulose Nutrition 0.000 abstract 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 abstract 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 abstract 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 abstract 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 abstract 1
- 229920000609 methyl cellulose Polymers 0.000 abstract 1
- 239000001923 methylcellulose Substances 0.000 abstract 1
- 235000010981 methylcellulose Nutrition 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 229960003893 phenacetin Drugs 0.000 abstract 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 abstract 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 abstract 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 abstract 1
- 239000007921 spray Substances 0.000 abstract 1
- 238000005507 spraying Methods 0.000 abstract 1
- 239000008107 starch Substances 0.000 abstract 1
- 235000019698 starch Nutrition 0.000 abstract 1
- 229960005404 sulfamethoxazole Drugs 0.000 abstract 1
- JLKIGFTWXXRPMT-UHFFFAOYSA-N sulphamethoxazole Chemical compound O1C(C)=CC(NS(=O)(=O)C=2C=CC(N)=CC=2)=N1 JLKIGFTWXXRPMT-UHFFFAOYSA-N 0.000 abstract 1
- 229910021653 sulphate ion Inorganic materials 0.000 abstract 1
- IEDVJHCEMCRBQM-UHFFFAOYSA-N trimethoprim Chemical compound COC1=C(OC)C(OC)=CC(CC=2C(=NC(N)=NC=2)N)=C1 IEDVJHCEMCRBQM-UHFFFAOYSA-N 0.000 abstract 1
- 229960001082 trimethoprim Drugs 0.000 abstract 1
- 239000000080 wetting agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH233173 | 1973-02-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1465781A true GB1465781A (en) | 1977-03-02 |
Family
ID=4231310
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB692974A Expired GB1465781A (en) | 1973-02-16 | 1974-02-15 | Pharmaceutical preparations |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US3907983A (enExample) |
| JP (1) | JPS49110820A (enExample) |
| AU (1) | AU6401073A (enExample) |
| BE (1) | BE811062A (enExample) |
| DE (1) | DE2404609B2 (enExample) |
| FR (1) | FR2218085B1 (enExample) |
| GB (1) | GB1465781A (enExample) |
| IL (1) | IL43853A0 (enExample) |
| NL (1) | NL7400298A (enExample) |
| ZA (1) | ZA739543B (enExample) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2155330A (en) * | 1984-03-08 | 1985-09-25 | Squibb & Sons Inc | Solvent granulation technique for forming solid formulation of nystatin |
| WO1993013783A1 (en) * | 1992-01-20 | 1993-07-22 | Holm Christensen Boerge | An iron-containing composition for the prevention of anaemia and a method for producing the composition |
| US5662922A (en) * | 1992-01-20 | 1997-09-02 | Christensen; Borge Holm | Iron-containing composition for the prevention of anaemia and a method for producing the composition |
| EP0580428B2 (en) † | 1992-07-24 | 2002-05-29 | Takeda Chemical Industries, Ltd. | Microparticle preparation and production thereof |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5438167B2 (enExample) * | 1974-04-27 | 1979-11-19 | ||
| US4291016A (en) * | 1976-07-27 | 1981-09-22 | Sandoz Ltd. | Enteric coated mixture of 4-(2-hydroxy-3-isopropylamino-propoxy) indole and sodium lauryl sulphate |
| US4122157A (en) | 1977-03-04 | 1978-10-24 | Richardson-Merrell Inc. | Nitrofurantoin sustained release tablet |
| JPS5668609A (en) | 1979-11-07 | 1981-06-09 | Nippon Kayaku Co Ltd | Phthalazinol preparation |
| US4252786A (en) * | 1979-11-16 | 1981-02-24 | E. R. Squibb & Sons, Inc. | Controlled release tablet |
| US4302440B1 (en) * | 1980-07-31 | 1986-08-05 | Easily-swallowed, powder-free and gastric-disintegrable aspirin tablet thinly-coated with hydroxypropyl methylcellulose and aqueous spray-coating preparation thereof | |
| US4508702A (en) * | 1982-06-14 | 1985-04-02 | Key Pharmaceuticals, Inc. | Sustained release aspirin |
| US4634587A (en) * | 1982-07-09 | 1987-01-06 | Key Pharmaceuticals, Inc. | Sustained release quinidine dosage form |
| US4684516A (en) * | 1983-08-01 | 1987-08-04 | Alra Laboratories, Inc. | Sustained release tablets and method of making same |
| US4555399A (en) * | 1983-11-18 | 1985-11-26 | Key Pharmaceuticals, Inc. | Aspirin tablet |
| SE457505B (sv) * | 1984-01-10 | 1989-01-09 | Lejus Medical Ab | Laminatbelagd oral farmaceutisk komposition och foerfarande foer dess framstaellning |
| JPH0753663B2 (ja) * | 1984-10-09 | 1995-06-07 | 武田薬品工業株式会社 | チアミン塩の顆粒,その製造法および錠剤 |
| ATE68695T1 (de) * | 1984-12-14 | 1991-11-15 | Gergely Gerhard | Teilchen aus einer hydrophoben oder schwerloeslichen substanz und verfahren zu ihrer hydrophilisierung. |
| US4747881A (en) * | 1985-02-05 | 1988-05-31 | Warner-Lambert Company | Ingestible aggregate and delivery system prepared therefrom |
| US4843098A (en) * | 1985-02-05 | 1989-06-27 | Warner-Lambert Company | Ingestible aggregate and delivery system prepared therefrom |
| US4851392A (en) * | 1985-02-05 | 1989-07-25 | Warner-Lambert Company | Ingestible aggregate and delivery system prepared therefrom |
| US4790991A (en) * | 1985-02-05 | 1988-12-13 | Warner-Lambert Company | Ingestible aggregate and delivery system prepared therefrom |
| US4818539A (en) * | 1985-02-05 | 1989-04-04 | Warner-Lambert Company | Ingestible aggregate and delivery system prepared therefrom |
| LU85943A1 (fr) * | 1985-06-12 | 1987-01-13 | Galephar | Comprimes pharmaceutiques permettant l'administration aisee de pellets, leur preparation et leur utilisation |
| US4710519A (en) * | 1985-09-30 | 1987-12-01 | Basf Corporation | Process for preparing spray dried acetaminophen powder and the powder prepared thereby |
| AU587863B2 (en) * | 1985-10-07 | 1989-08-31 | Basf Aktiengesellschaft | Vitamin-containing granules and production thereof |
| US4837033A (en) * | 1987-12-22 | 1989-06-06 | Shin-Etsu Chemical Co., Ltd. | Method for the preparation of a coated solid medicament |
| JP2669446B2 (ja) * | 1992-03-23 | 1997-10-27 | 信越化学工業株式会社 | 医薬品コーティング液用原料粉粒体 |
| US5560927A (en) * | 1995-07-28 | 1996-10-01 | Isp Investments Inc. | Co-processing method for making a free-flowing compressible powder and tablet therefrom |
| JP3555640B2 (ja) * | 1996-05-10 | 2004-08-18 | ライオン株式会社 | 天然カロチノイドを包含した多芯型構造のマイクロカプセル並びに錠剤、食品用及び医薬品用配合剤 |
| US20070202182A1 (en) * | 2006-02-26 | 2007-08-30 | Kane Kevin M | Preparing solid formulation of nanoparticles of pharmaceutical ingredient, including at least micron-sized particles |
| US20100034959A1 (en) * | 2008-08-07 | 2010-02-11 | Vector Corporation | High solids, high molecular weight polymer coating |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1492034A1 (de) * | 1965-05-18 | 1969-02-20 | Merck Ag E | Verfahren zur Herstellung fester haltbarer Zubereitungen von empfindlichen,in Wasser schwer loeslichen Wirkstoffen,vorzugsweise Arzneimitteln |
| AU1039170A (en) * | 1969-02-24 | 1971-07-22 | Abbott Laboratories | Tableting medium |
| NL7112083A (enExample) * | 1970-09-16 | 1972-03-20 |
-
1973
- 1973-12-18 ZA ZA00739543A patent/ZA739543B/xx unknown
- 1973-12-18 IL IL43853A patent/IL43853A0/xx unknown
- 1973-12-28 AU AU64010/73A patent/AU6401073A/en not_active Expired
-
1974
- 1974-01-09 NL NL7400298A patent/NL7400298A/xx not_active Application Discontinuation
- 1974-01-30 US US438135*A patent/US3907983A/en not_active Expired - Lifetime
- 1974-01-31 DE DE2404609A patent/DE2404609B2/de not_active Ceased
- 1974-02-14 FR FR7405017A patent/FR2218085B1/fr not_active Expired
- 1974-02-14 JP JP49017211A patent/JPS49110820A/ja active Pending
- 1974-02-15 BE BE140933A patent/BE811062A/xx unknown
- 1974-02-15 GB GB692974A patent/GB1465781A/en not_active Expired
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2155330A (en) * | 1984-03-08 | 1985-09-25 | Squibb & Sons Inc | Solvent granulation technique for forming solid formulation of nystatin |
| WO1993013783A1 (en) * | 1992-01-20 | 1993-07-22 | Holm Christensen Boerge | An iron-containing composition for the prevention of anaemia and a method for producing the composition |
| US5662922A (en) * | 1992-01-20 | 1997-09-02 | Christensen; Borge Holm | Iron-containing composition for the prevention of anaemia and a method for producing the composition |
| EP0580428B2 (en) † | 1992-07-24 | 2002-05-29 | Takeda Chemical Industries, Ltd. | Microparticle preparation and production thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2218085A1 (enExample) | 1974-09-13 |
| DE2404609B2 (de) | 1978-05-18 |
| US3907983A (en) | 1975-09-23 |
| JPS49110820A (enExample) | 1974-10-22 |
| BE811062A (fr) | 1974-08-16 |
| AU6401073A (en) | 1975-07-03 |
| NL7400298A (enExample) | 1974-08-20 |
| DE2404609A1 (de) | 1974-09-05 |
| FR2218085B1 (enExample) | 1977-11-10 |
| ZA739543B (en) | 1975-03-26 |
| IL43853A0 (en) | 1974-03-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |