GB1456162A - Thienodiazepine derivatives - Google Patents
Thienodiazepine derivativesInfo
- Publication number
- GB1456162A GB1456162A GB539676A GB539676A GB1456162A GB 1456162 A GB1456162 A GB 1456162A GB 539676 A GB539676 A GB 539676A GB 539676 A GB539676 A GB 539676A GB 1456162 A GB1456162 A GB 1456162A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- alkanoyl
- alkoxycarbonyl
- hydroxyalkyl
- feb
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/36—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Abstract
1456162 Thienodiazepines F HOFFMANNLA ROCHE & CO AG 7 Feb 1974 [8 Feb 1973] 05396/76 Divided out of 1456161 Heading C2C Compounds of the general formula (R 1 = halogen, NO 2 , NH 2 , alkanoyl; R 2 = pyridyl or thienyl optionally substituted adjacent to linking position, phenyl, o-trifluoromethylphenyl, o - halophenyl, o,o<SP>1</SP> - dihalophenyl, o - nitrophenyl; R 3 = H, OH, alkoxycarbonyl, alkanoyloxy; R 4 = H, alkyl, alkanoyl, hydroxyalkyl, mercaptoalkyl, alkoxycarbonyl, aminocarbonyl, haloalkyl, alkoxyalkyl, alkylthioalkyl, aralkoxyalkyl, cyanoalkyl, alkoxycarbonylalkyl, alkoxycarbonylaminoalkyl, alkylcarbonyloxyalkyl, aminocarbonyloxyalkyl, dialkylaminocarbonyloxyalkyl, CN, alkyl NR 5 R 6 , COO alkyl NR 5 R 6 , CONH alkyl NR 5 R 6 ; R 5,6 = H, alkyl, hydroxyalkyl or NR 5 R 6 = monocyclic saturated 5-6 membered ring optionally containing an oxygen or further nitrogen atom ; n = 0, 1) are prepared by standard methods, e.g. condensing the corresponding 5- aryl - 1,3 - dihydro - 2H - thieno[2,3-e] - 1,4- diazepine-2-thione with R 4 CONHNH 2 .
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH179973A CH584223A5 (en) | 1973-02-08 | 1973-02-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1456162A true GB1456162A (en) | 1976-11-17 |
Family
ID=4218866
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB568374A Expired GB1456161A (en) | 1973-02-08 | 1974-02-07 | Diazepine derivatives |
| GB539676A Expired GB1456162A (en) | 1973-02-08 | 1974-02-07 | Thienodiazepine derivatives |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB568374A Expired GB1456161A (en) | 1973-02-08 | 1974-02-07 | Diazepine derivatives |
Country Status (24)
| Country | Link |
|---|---|
| JP (1) | JPS5833234B2 (en) |
| AR (2) | AR203188A1 (en) |
| AT (1) | AT343118B (en) |
| BE (1) | BE810705A (en) |
| CA (1) | CA1049009A (en) |
| CH (1) | CH584223A5 (en) |
| DD (1) | DD112454A5 (en) |
| DE (1) | DE2405682C3 (en) |
| DK (1) | DK137679B (en) |
| FI (1) | FI58129C (en) |
| FR (1) | FR2217007B1 (en) |
| GB (2) | GB1456161A (en) |
| HU (2) | HU170423B (en) |
| IE (1) | IE38883B1 (en) |
| IL (1) | IL44095A (en) |
| LU (1) | LU69338A1 (en) |
| NL (1) | NL174045C (en) |
| NO (1) | NO142260C (en) |
| PH (1) | PH12303A (en) |
| PL (3) | PL97304B1 (en) |
| SE (1) | SE416399B (en) |
| SU (3) | SU715028A3 (en) |
| YU (1) | YU39716B (en) |
| ZA (1) | ZA74472B (en) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT338799B (en) * | 1974-03-02 | 1977-09-12 | Boehringer Sohn Ingelheim | PROCESS FOR PREPARING NEW SUBSTITUTED 6-ARYL-4H-S-TRIAZOLO- (3,4C) -THIENO- (2,3E) -1,4-DIAZEPINE AND THEIR SALTS |
| DE2533924C3 (en) * | 1975-07-30 | 1979-05-03 | C.H. Boehringer Sohn, 6507 Ingelheim | Process for the preparation of 6-aryl-4H-striazolo [3,4-c] thieno [2,3-e] 1,4-diazepines |
| DE2531678C3 (en) * | 1975-07-16 | 1979-06-28 | C.H. Boehringer Sohn, 6507 Ingelheim | Thieno [2,3e] triazole [3,4c] 5,6-dihydro-1,4-diazepines and processes for their preparation |
| DE2708121A1 (en) * | 1977-02-25 | 1978-09-07 | Boehringer Sohn Ingelheim | TRIAZOLO-THIENO-DIAZEPIN-L-ONE, METHOD FOR THEIR PRODUCTION AND MEDICINAL PRODUCTS |
| FI63033C (en) * | 1977-07-21 | 1983-04-11 | Boehringer Sohn Ingelheim | FREQUENCY REQUIREMENT FOR ANXIOLYTIC TRANSQUILLATION OF SEED / ELLER NEUROLEPTIC SUBSTITUTES 1-PIPERAZINYL-4H-S-TRIAZOLO (3,4-C) THIENO (2,3-E) -1,4-DIAZEPERE |
| DE3502392A1 (en) * | 1985-01-25 | 1986-07-31 | Boehringer Ingelheim KG, 6507 Ingelheim | NEW THIENO-TRIAZOLO-1,4-DIAZEPINO-2-CARBONIC ACID AMIDES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS |
| DE3778559D1 (en) * | 1986-01-21 | 1992-06-04 | Boehringer Ingelheim Kg | THIENO-1,4-DIAZEPINE. |
| JP2582225B2 (en) * | 1994-04-15 | 1997-02-19 | ナショナル住宅産業株式会社 | Fittings |
| WO1995032963A1 (en) * | 1994-06-01 | 1995-12-07 | Yoshitomi Pharmaceutical Industries, Ltd. | Thienylazole compound and thienotriazolodiazepine compound |
| CN1101680C (en) * | 1995-09-09 | 2003-02-19 | 弗·哈夫曼-拉罗切有限公司 | Use of thienotriazolodiazepine to increase apolipoprotein A-I levels |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3904641A (en) * | 1971-06-18 | 1975-09-09 | Yoshitomi Pharmaceutical | Triazolothienodiazepine compounds |
-
1973
- 1973-01-29 PH PH7315453A patent/PH12303A/en unknown
- 1973-02-08 CH CH179973A patent/CH584223A5/xx not_active IP Right Cessation
-
1974
- 1974-01-22 ZA ZA740472A patent/ZA74472B/en unknown
- 1974-01-28 NL NLAANVRAGE7401117,A patent/NL174045C/en not_active IP Right Cessation
- 1974-01-28 IL IL44095A patent/IL44095A/en unknown
- 1974-01-30 YU YU2287/74A patent/YU39716B/en unknown
- 1974-02-06 LU LU69338A patent/LU69338A1/xx unknown
- 1974-02-06 IE IE00221/74A patent/IE38883B1/en unknown
- 1974-02-06 DD DD176414A patent/DD112454A5/xx unknown
- 1974-02-06 CA CA74191917A patent/CA1049009A/en not_active Expired
- 1974-02-06 DE DE2405682A patent/DE2405682C3/en not_active Expired
- 1974-02-06 FR FR7403922A patent/FR2217007B1/fr not_active Expired
- 1974-02-07 GB GB568374A patent/GB1456161A/en not_active Expired
- 1974-02-07 PL PL1974191791A patent/PL97304B1/en unknown
- 1974-02-07 DK DK66874AA patent/DK137679B/en unknown
- 1974-02-07 BE BE140629A patent/BE810705A/en not_active IP Right Cessation
- 1974-02-07 PL PL1974191789A patent/PL97275B1/en unknown
- 1974-02-07 PL PL1974168647A patent/PL96107B1/en unknown
- 1974-02-07 HU HUHO1644A patent/HU170423B/hu unknown
- 1974-02-07 HU HU74HO1865A patent/HU173741B/en unknown
- 1974-02-07 GB GB539676A patent/GB1456162A/en not_active Expired
- 1974-02-07 NO NO740405A patent/NO142260C/en unknown
- 1974-02-07 SE SE7401664A patent/SE416399B/en not_active IP Right Cessation
- 1974-02-07 SU SU741994653A patent/SU715028A3/en active
- 1974-02-07 AT AT96474A patent/AT343118B/en not_active IP Right Cessation
- 1974-02-08 FI FI357/74A patent/FI58129C/en active
- 1974-02-08 AR AR252265A patent/AR203188A1/en active
- 1974-02-08 JP JP49015549A patent/JPS5833234B2/en not_active Expired
- 1974-12-04 AR AR256777A patent/AR217034A1/en active
-
1978
- 1978-06-10 SU SU782633846A patent/SU1060115A3/en active
- 1978-07-10 SU SU782633659A patent/SU747429A4/en active
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| 704A | Declaration that licence is not available as of right for an excepted use (par. 4a/1977) | ||
| 732 | Registration of transactions, instruments or events in the register (sect. 32/1977) | ||
| PCNP | Patent ceased through non-payment of renewal fee |