GB1418363A - Process for the production of 6-piper-azinyl-morphanthridines and related tricyclics - Google Patents

Process for the production of 6-piper-azinyl-morphanthridines and related tricyclics

Info

Publication number
GB1418363A
GB1418363A GB1566773A GB1566773A GB1418363A GB 1418363 A GB1418363 A GB 1418363A GB 1566773 A GB1566773 A GB 1566773A GB 1566773 A GB1566773 A GB 1566773A GB 1418363 A GB1418363 A GB 1418363A
Authority
GB
United Kingdom
Prior art keywords
thiophene
acid
alkyl
reaction
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1566773A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wander AG
Original Assignee
Wander AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wander AG filed Critical Wander AG
Publication of GB1418363A publication Critical patent/GB1418363A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30Hetero atoms other than halogen
    • C07D333/32Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GB1566773A 1972-04-04 1973-04-02 Process for the production of 6-piper-azinyl-morphanthridines and related tricyclics Expired GB1418363A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH489872A CH569730A5 (fi) 1972-04-04 1972-04-04
CH490172A CH569731A5 (fi) 1972-04-04 1972-04-04

Publications (1)

Publication Number Publication Date
GB1418363A true GB1418363A (en) 1975-12-17

Family

ID=25696493

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1566773A Expired GB1418363A (en) 1972-04-04 1973-04-02 Process for the production of 6-piper-azinyl-morphanthridines and related tricyclics

Country Status (28)

Country Link
JP (2) JPS4913189A (fi)
AR (1) AR195913A1 (fi)
AT (1) AT340428B (fi)
BE (1) BE797671A (fi)
BG (1) BG21221A3 (fi)
CA (1) CA1029372A (fi)
CH (2) CH569731A5 (fi)
CS (1) CS178125B2 (fi)
CY (1) CY990A (fi)
DD (1) DD105614A5 (fi)
DK (1) DK150850C (fi)
ES (1) ES413252A1 (fi)
FI (1) FI61029C (fi)
FR (1) FR2179071B1 (fi)
GB (1) GB1418363A (fi)
HK (1) HK11079A (fi)
HU (1) HU166524B (fi)
IL (1) IL41936A (fi)
LU (1) LU67351A1 (fi)
MY (1) MY7900116A (fi)
NL (1) NL175621C (fi)
NO (1) NO138210C (fi)
PH (1) PH11180A (fi)
PL (1) PL89178B1 (fi)
RO (1) RO72458A (fi)
SE (1) SE399890B (fi)
SU (1) SU457220A3 (fi)
YU (1) YU39906B (fi)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7491715B2 (en) 2003-12-22 2009-02-17 Acadia Pharmaceuticals, Inc. Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7403657A (fi) * 1973-03-23 1974-09-25
JPS51135089A (en) * 1975-05-19 1976-11-22 Hitachi Zosen Corp Under-water operation assistant ship
IT1207417B (it) * 1982-03-15 1989-05-17 Menarini Sas Azepina-6-one ad attivita'composti triciclici derivati dalla farmacologica, e procedimenti di 5,6-diidro-11h-dibenzo (b,e)fabbricazione relativi
GB8607684D0 (en) * 1986-03-27 1986-04-30 Ici America Inc Thiazepine compounds
PT2307389E (pt) 2008-06-20 2013-03-28 Astrazeneca Ab Derivados de dibenzotiazepina e sua utilização

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7491715B2 (en) 2003-12-22 2009-02-17 Acadia Pharmaceuticals, Inc. Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders
US7517871B2 (en) 2003-12-22 2009-04-14 Acadia Pharmaceuticals, Inc. Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders
US7550454B2 (en) 2003-12-22 2009-06-23 Acadia Pharmaceuticals, Inc. Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders
US7622461B2 (en) 2003-12-22 2009-11-24 Acadia Pharmaceuticals Inc. Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders

Also Published As

Publication number Publication date
CS178125B2 (fi) 1977-08-31
CH569731A5 (fi) 1975-11-28
CA1029372A (en) 1978-04-11
IL41936A (en) 1977-10-31
JPS5142118B2 (fi) 1976-11-13
NO138210B (no) 1978-04-17
FR2179071A1 (fi) 1973-11-16
FI61029B (fi) 1982-01-29
BE797671A (fr) 1973-10-02
DE2316438B2 (de) 1976-06-16
DK150850C (da) 1987-11-30
IL41936A0 (en) 1973-06-29
PH11180A (en) 1977-10-28
SU457220A3 (ru) 1975-01-15
DD105614A5 (fi) 1974-05-05
NL7304441A (fi) 1973-10-08
JPS4913189A (fi) 1974-02-05
PL89178B1 (fi) 1976-10-30
NO138210C (no) 1978-07-26
AT340428B (de) 1977-12-12
DE2316438A1 (de) 1973-10-11
HK11079A (en) 1979-03-16
DK150850B (da) 1987-07-06
AR195913A1 (es) 1973-11-15
LU67351A1 (fi) 1973-10-15
HU166524B (fi) 1975-03-28
ATA291173A (de) 1977-04-15
RO72458A (ro) 1981-02-28
ES413252A1 (es) 1976-05-01
YU39906B (en) 1985-06-30
NL175621C (nl) 1984-12-03
FI61029C (fi) 1982-05-10
FR2179071B1 (fi) 1977-02-04
CH569730A5 (fi) 1975-11-28
YU88173A (en) 1982-06-30
JPS4913190A (fi) 1974-02-05
BG21221A3 (bg) 1976-03-20
CY990A (en) 1979-08-02
MY7900116A (en) 1979-12-31
SE399890B (sv) 1978-03-06

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PE20 Patent expired after termination of 20 years

Effective date: 19930401