GB1384488A - Stabilized n6-2,0-dibutyryladenosine-3,5,-cyclic phosphate salts and production thereof - Google Patents
Stabilized n6-2,0-dibutyryladenosine-3,5,-cyclic phosphate salts and production thereofInfo
- Publication number
- GB1384488A GB1384488A GB4695673A GB4695673A GB1384488A GB 1384488 A GB1384488 A GB 1384488A GB 4695673 A GB4695673 A GB 4695673A GB 4695673 A GB4695673 A GB 4695673A GB 1384488 A GB1384488 A GB 1384488A
- Authority
- GB
- United Kingdom
- Prior art keywords
- moisture content
- drying
- weight
- cyclic phosphate
- stabilized
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000001035 drying Methods 0.000 abstract 4
- 239000002274 desiccant Substances 0.000 abstract 3
- 238000004108 freeze drying Methods 0.000 abstract 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 2
- 229910019142 PO4 Inorganic materials 0.000 abstract 2
- 230000000052 comparative effect Effects 0.000 abstract 2
- 230000018044 dehydration Effects 0.000 abstract 2
- 238000006297 dehydration reaction Methods 0.000 abstract 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 2
- 239000010452 phosphate Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 abstract 1
- 229910004298 SiO 2 Inorganic materials 0.000 abstract 1
- 150000001298 alcohols Chemical class 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 150000003863 ammonium salts Chemical class 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 238000000354 decomposition reaction Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 159000000000 sodium salts Chemical class 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 238000001694 spray drying Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP47100642A JPS5134443B2 (enExample) | 1972-10-09 | 1972-10-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1384488A true GB1384488A (en) | 1975-02-19 |
Family
ID=14279465
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4695673A Expired GB1384488A (en) | 1972-10-09 | 1973-10-08 | Stabilized n6-2,0-dibutyryladenosine-3,5,-cyclic phosphate salts and production thereof |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JPS5134443B2 (enExample) |
| DE (1) | DE2350228C3 (enExample) |
| FR (1) | FR2202091B1 (enExample) |
| GB (1) | GB1384488A (enExample) |
| NL (1) | NL151381B (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1441706A (en) * | 1973-04-06 | 1976-07-07 | Yamasa Shoyu Kk | Crystalline monosodium n6, 2-o-dibutyryl-adenosine-3-5-cyclic monophosphate and production thereof |
| JPS50142595A (enExample) * | 1974-05-14 | 1975-11-17 | ||
| JP2740362B2 (ja) * | 1991-02-12 | 1998-04-15 | ヤマサ醤油株式会社 | 安定な固体状２‐オクチニルアデノシンおよびその製造法 |
-
1972
- 1972-10-09 JP JP47100642A patent/JPS5134443B2/ja not_active Expired
-
1973
- 1973-10-05 DE DE19732350228 patent/DE2350228C3/de not_active Expired
- 1973-10-08 FR FR7335835A patent/FR2202091B1/fr not_active Expired
- 1973-10-08 NL NL7313793A patent/NL151381B/xx not_active IP Right Cessation
- 1973-10-08 GB GB4695673A patent/GB1384488A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR2202091B1 (enExample) | 1977-05-27 |
| NL7313793A (enExample) | 1974-04-11 |
| DE2350228B2 (de) | 1975-03-27 |
| JPS4955814A (enExample) | 1974-05-30 |
| JPS5134443B2 (enExample) | 1976-09-27 |
| NL151381B (nl) | 1976-11-15 |
| DE2350228A1 (de) | 1974-05-02 |
| FR2202091A1 (enExample) | 1974-05-03 |
| DE2350228C3 (de) | 1975-11-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 19921008 |