GB1361967A - Pyrazine 4-oxide derivatives and process for their preparation - Google Patents

Pyrazine 4-oxide derivatives and process for their preparation

Info

Publication number
GB1361967A
GB1361967A GB1764573A GB1764573A GB1361967A GB 1361967 A GB1361967 A GB 1361967A GB 1764573 A GB1764573 A GB 1764573A GB 1764573 A GB1764573 A GB 1764573A GB 1361967 A GB1361967 A GB 1361967A
Authority
GB
United Kingdom
Prior art keywords
general formula
compound
group
pyrazine
april
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1764573A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Carlo Erba SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carlo Erba SpA filed Critical Carlo Erba SpA
Publication of GB1361967A publication Critical patent/GB1361967A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
GB1764573A 1972-04-28 1973-04-12 Pyrazine 4-oxide derivatives and process for their preparation Expired GB1361967A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2366372 1972-04-28

Publications (1)

Publication Number Publication Date
GB1361967A true GB1361967A (en) 1974-07-30

Family

ID=11208983

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1764573A Expired GB1361967A (en) 1972-04-28 1973-04-12 Pyrazine 4-oxide derivatives and process for their preparation

Country Status (21)

Country Link
JP (1) JPS5535384B2 (de)
AT (1) AT326669B (de)
AU (1) AU470007B2 (de)
BE (1) BE798752A (de)
CA (1) CA1000278A (de)
CH (1) CH582161A5 (de)
CS (1) CS172972B2 (de)
DE (1) DE2319834C3 (de)
DK (1) DK138796B (de)
FI (1) FI55033C (de)
FR (1) FR2183049B1 (de)
GB (1) GB1361967A (de)
HK (1) HK66876A (de)
HU (1) HU165674B (de)
IL (1) IL42026A (de)
MY (1) MY7700077A (de)
NL (1) NL178595C (de)
NO (1) NO137728C (de)
SE (1) SE387344B (de)
SU (1) SU578876A3 (de)
ZA (1) ZA732712B (de)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3219407A1 (de) * 1981-05-28 1983-01-05 Farmitalia Carlo Erba S.p.A., 20159 Milano Verfahren zur herstellung von pyrazinderivaten
EP0088395A1 (de) * 1982-03-08 1983-09-14 FARMITALIA CARLO ERBA S.p.A. Verfahren zur Herstellung von Pyrazin-Derivaten
US4962111A (en) * 1989-06-08 1990-10-09 The Research Foundation Of State University Of New York Pyrazinoic acid esters as antituberculosis agents
US5643912A (en) * 1993-12-17 1997-07-01 The Research Foundation Of State University Of Ny Pyrazinoic acid esters as anti-mycobacterium avium agents
WO2021203572A1 (zh) * 2020-04-08 2021-10-14 山东新时代药业有限公司 一种 1,2- 二 (4- 吡啶基 ) 乙烷 - 阿昔莫司共晶

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1094287B (it) * 1978-03-23 1985-07-26 Erba Carlo Spa Derivati della 2-idrossimetil-pirazina aventi attivita' ipolipemizzante
EP0112617B1 (de) * 1982-11-04 1986-12-30 Imperial Chemical Industries Plc Verfahren zur Extraktion von Metallwerkstoffen und Metallextrahierern
IT1201417B (it) * 1985-05-17 1989-02-02 Montedison Spa Procedimento per la preparazione di 2-carbossipirazine 4 ossido

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3452014A (en) * 1964-08-14 1969-06-24 Upjohn Co 2,5-dimethylpyrazine p-toluenesulfonate
AT291264B (de) * 1969-05-05 1971-07-12 Daiichi Seiyaku Company Ltd Verfahren zur Herstellung von neuen Pyrazincarbonsäurederivaten
NL6907199A (en) * 1969-05-09 1970-11-11 Hypoglycaemic pyrazine derivs

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3219407A1 (de) * 1981-05-28 1983-01-05 Farmitalia Carlo Erba S.p.A., 20159 Milano Verfahren zur herstellung von pyrazinderivaten
EP0088395A1 (de) * 1982-03-08 1983-09-14 FARMITALIA CARLO ERBA S.p.A. Verfahren zur Herstellung von Pyrazin-Derivaten
US4511718A (en) * 1982-03-08 1985-04-16 Farmitalia Carlo Erba S.P.A. Preparation of pyrazine derivatives
US4962111A (en) * 1989-06-08 1990-10-09 The Research Foundation Of State University Of New York Pyrazinoic acid esters as antituberculosis agents
US5643912A (en) * 1993-12-17 1997-07-01 The Research Foundation Of State University Of Ny Pyrazinoic acid esters as anti-mycobacterium avium agents
WO2021203572A1 (zh) * 2020-04-08 2021-10-14 山东新时代药业有限公司 一种 1,2- 二 (4- 吡啶基 ) 乙烷 - 阿昔莫司共晶

Also Published As

Publication number Publication date
CA1000278A (en) 1976-11-23
CS172972B2 (de) 1977-01-28
BE798752A (fr) 1973-08-16
DE2319834B2 (de) 1982-06-24
ATA345073A (de) 1975-03-15
AU470007B2 (en) 1976-02-26
JPS5535384B2 (de) 1980-09-12
MY7700077A (en) 1977-12-31
AT326669B (de) 1975-12-29
FR2183049A1 (de) 1973-12-14
AU5441373A (en) 1974-10-17
DK138796B (da) 1978-10-30
SU578876A3 (ru) 1977-10-30
HU165674B (de) 1974-10-28
NL178595C (nl) 1986-04-16
DE2319834C3 (de) 1983-02-03
CH582161A5 (de) 1976-11-30
IL42026A (en) 1976-07-30
IL42026A0 (en) 1973-06-29
NL7305867A (de) 1973-10-30
FI55033B (fi) 1979-01-31
DE2319834A1 (de) 1973-11-15
ZA732712B (en) 1974-11-27
FI55033C (fi) 1979-05-10
NO137728C (no) 1978-04-12
NO137728B (no) 1978-01-02
FR2183049B1 (de) 1975-10-31
NL178595B (nl) 1985-11-18
DK138796C (de) 1979-04-30
SE387344B (sv) 1976-09-06
JPS4954386A (de) 1974-05-27
HK66876A (en) 1976-11-05

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
732 Registration of transactions, instruments or events in the register (sect. 32/1977)
PE20 Patent expired after termination of 20 years

Effective date: 19930411