GB1359009A - 1-vinylcarbonyl-piperazine derivatives having an analgesic action and process for preparing them - Google Patents
1-vinylcarbonyl-piperazine derivatives having an analgesic action and process for preparing themInfo
- Publication number
- GB1359009A GB1359009A GB5972371A GB5972371A GB1359009A GB 1359009 A GB1359009 A GB 1359009A GB 5972371 A GB5972371 A GB 5972371A GB 5972371 A GB5972371 A GB 5972371A GB 1359009 A GB1359009 A GB 1359009A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- dec
- vinylcarbonyl
- preparing
- piperazine derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- ZVUAMUKZHFTJGR-UHFFFAOYSA-N 1-piperazin-1-ylprop-2-en-1-one Chemical class C=CC(=O)N1CCNCC1 ZVUAMUKZHFTJGR-UHFFFAOYSA-N 0.000 title 1
- 230000000202 analgesic effect Effects 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 229940035676 analgesics Drugs 0.000 abstract 2
- 239000000730 antalgic agent Substances 0.000 abstract 2
- RYYVLZVUVIJVGH-UHFFFAOYSA-N caffeine Chemical compound CN1C(=O)N(C)C(=O)C2=C1N=CN2C RYYVLZVUVIJVGH-UHFFFAOYSA-N 0.000 abstract 2
- 125000001475 halogen functional group Chemical group 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- AZEIRPAUJXANCS-UHFFFAOYSA-N 4-ethoxybenzamide Chemical compound CCOC1=CC=C(C(N)=O)C=C1 AZEIRPAUJXANCS-UHFFFAOYSA-N 0.000 abstract 1
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 abstract 1
- LPHGQDQBBGAPDZ-UHFFFAOYSA-N Isocaffeine Natural products CN1C(=O)N(C)C(=O)C2=C1N(C)C=N2 LPHGQDQBBGAPDZ-UHFFFAOYSA-N 0.000 abstract 1
- 229960001138 acetylsalicylic acid Drugs 0.000 abstract 1
- 230000001754 anti-pyretic effect Effects 0.000 abstract 1
- 239000002221 antipyretic Substances 0.000 abstract 1
- 229940125716 antipyretic agent Drugs 0.000 abstract 1
- 229960001948 caffeine Drugs 0.000 abstract 1
- VJEONQKOZGKCAK-UHFFFAOYSA-N caffeine Natural products CN1C(=O)N(C)C(=O)C2=C1C=CN2C VJEONQKOZGKCAK-UHFFFAOYSA-N 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 229940083251 peripheral vasodilators purine derivative Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- CPJSUEIXXCENMM-UHFFFAOYSA-N phenacetin Chemical compound CCOC1=CC=C(NC(C)=O)C=C1 CPJSUEIXXCENMM-UHFFFAOYSA-N 0.000 abstract 1
- 229960003893 phenacetin Drugs 0.000 abstract 1
- 150000003212 purines Chemical class 0.000 abstract 1
- DNXIASIHZYFFRO-UHFFFAOYSA-N pyrazoline Chemical compound C1CN=NC1 DNXIASIHZYFFRO-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
- C07C47/24—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
- C07C47/277—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pile Receivers (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19702063384 DE2063384A1 (de) | 1970-12-23 | 1970-12-23 | l-(l,2-Diphenyl-2-formylvinyl)-4methylpiperazin und seine physiologisch verträglichen Salze und Verfahren zu seiner Herstellung |
| DE2160235A DE2160235A1 (de) | 1971-12-04 | 1971-12-04 | Analgetisch wirksame 1-vinylcarbonylpiperazinderivate und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1359009A true GB1359009A (en) | 1974-07-03 |
Family
ID=25760226
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5972371A Expired GB1359009A (en) | 1970-12-23 | 1971-12-22 | 1-vinylcarbonyl-piperazine derivatives having an analgesic action and process for preparing them |
Country Status (13)
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4182730A (en) * | 1977-11-25 | 1980-01-08 | Givaudan Corporation | Process for the preparation of substituted dihydrocinnamaldehydes via novel β-chlorocinnamaldehydes |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE944852C (de) * | 1949-11-30 | 1956-06-28 | Basf Ag | Verfahren zur Herstellung von Derivaten des 3-Amino-acroleins |
-
1971
- 1971-12-17 NL NL7117365A patent/NL7117365A/xx unknown
- 1971-12-20 CH CH1859571A patent/CH575937A5/xx not_active IP Right Cessation
- 1971-12-20 CA CA130,489A patent/CA971173A/en not_active Expired
- 1971-12-21 AU AU37154/71A patent/AU464778B2/en not_active Expired
- 1971-12-21 IL IL38415A patent/IL38415A/xx unknown
- 1971-12-22 AT AT1103171A patent/AT321306B/de not_active IP Right Cessation
- 1971-12-22 DD DD166617A patent/DD102301A5/xx unknown
- 1971-12-22 PL PL1971152415A patent/PL82643B1/pl unknown
- 1971-12-22 DD DD159818A patent/DD97202A5/xx unknown
- 1971-12-22 GB GB5972371A patent/GB1359009A/en not_active Expired
- 1971-12-23 FR FR7146368A patent/FR2119052B1/fr not_active Expired
- 1971-12-23 SE SE7116571A patent/SE376608B/xx unknown
- 1971-12-23 NO NO4820/71A patent/NO133232C/no unknown
- 1971-12-23 HU HUHO1444A patent/HU163714B/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL7117365A (enrdf_load_stackoverflow) | 1972-06-27 |
| AT321306B (de) | 1975-03-25 |
| AU3715471A (en) | 1973-06-28 |
| IL38415A (en) | 1975-05-22 |
| NO133232C (enrdf_load_stackoverflow) | 1976-03-31 |
| CH575937A5 (enrdf_load_stackoverflow) | 1976-05-31 |
| SE376608B (enrdf_load_stackoverflow) | 1975-06-02 |
| DD102301A5 (enrdf_load_stackoverflow) | 1973-12-12 |
| FR2119052B1 (enrdf_load_stackoverflow) | 1975-03-14 |
| IL38415A0 (en) | 1972-02-29 |
| FR2119052A1 (enrdf_load_stackoverflow) | 1972-08-04 |
| PL82643B1 (enrdf_load_stackoverflow) | 1975-10-31 |
| DD97202A5 (enrdf_load_stackoverflow) | 1973-04-20 |
| HU163714B (enrdf_load_stackoverflow) | 1973-10-27 |
| AU464778B2 (en) | 1975-09-04 |
| NO133232B (enrdf_load_stackoverflow) | 1975-12-22 |
| CA971173A (en) | 1975-07-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1199233A (en) | New Derivatives of D-6-Methylergoline(I) and a Method of Producing Same | |
| GB1147379A (en) | 4-alkyl-dialkoxy-ª‡-methylphenethylamines and pharmacologically acceptable salts | |
| GB1456627A (en) | Pyridobenzodiazepinones | |
| ES375203A1 (es) | Un procedimiento para preparar un derivado de benzotiazepi-na. | |
| GB1367785A (en) | 2-substituted adenosine derivatives and the production thereof | |
| GB1359009A (en) | 1-vinylcarbonyl-piperazine derivatives having an analgesic action and process for preparing them | |
| GB1394568A (en) | Diazepine derivatives and process for the production thereof | |
| GB1181967A (en) | Novel Picoline Derivatives and a Method for the Production Thereof | |
| GB1276968A (en) | Improvements in or relating to phenylacetamides and the preparation thereof | |
| GB1490169A (en) | N-vinyloxyethyl-alpha-methyl-beta-phenethylamines | |
| GB1184826A (en) | Substituted Aryloxy Hydroxy Amines | |
| DK174584D0 (da) | Penemer,farmaceutiske praeparater indeholdende disse,samt fremgangsmaader til fremstilling deraf | |
| GB850298A (en) | ª‡,ª‡[(p-chlorophenyl)-(4-pyridyl)] carbinols and method of preparing same | |
| GB1512653A (en) | Indazoles and the like | |
| GB1335403A (en) | Pharmaceutical compositions containing benzofuran derivatives | |
| GB1299289A (en) | Piperidine derivatives | |
| GB1222947A (en) | Thiophene derivatives | |
| GB1132397A (en) | Improvements in or relating to fluorene derivatives and the manufacture thereof | |
| GB1248471A (en) | New proline derivatives and process for the preparation thereof | |
| GB1184649A (en) | N-Substituted 2-Hydroxymorphinanes and Pharmaceutical Compositions containing them | |
| GB1368251A (en) | Theophylinylmethylethanoic acid ester | |
| GB1217427A (en) | Cinchona alkaloid derivatives | |
| SE333735B (enrdf_load_stackoverflow) | ||
| GB1264128A (enrdf_load_stackoverflow) | ||
| GB1097553A (en) | An acylated amino alcohol, process for its preparation and pharmaceutical compositions containing it |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |