GB1359009A - 1-vinylcarbonyl-piperazine derivatives having an analgesic action and process for preparing them - Google Patents

1-vinylcarbonyl-piperazine derivatives having an analgesic action and process for preparing them

Info

Publication number
GB1359009A
GB1359009A GB5972371A GB5972371A GB1359009A GB 1359009 A GB1359009 A GB 1359009A GB 5972371 A GB5972371 A GB 5972371A GB 5972371 A GB5972371 A GB 5972371A GB 1359009 A GB1359009 A GB 1359009A
Authority
GB
United Kingdom
Prior art keywords
alkyl
dec
vinylcarbonyl
preparing
piperazine derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5972371A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Farbwerke Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19702063384 external-priority patent/DE2063384A1/en
Priority claimed from DE2160235A external-priority patent/DE2160235A1/en
Application filed by Hoechst AG, Farbwerke Hoechst AG filed Critical Hoechst AG
Publication of GB1359009A publication Critical patent/GB1359009A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/24—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/277—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pile Receivers (AREA)

Abstract

1359009 Analgesics FARBWERKE HOECHST AG 22 Dec 1971 [23 Dec 1970 4 Dec 1971] 59723/71 Heading A5B [Also in Division C2] Pharmaceutical compositions for oral or parenteral administration as analgesics comprise a compound I in which R 1 is H, 1-4C alkyl, or phenyl optionally substituted by one or two of halo and 1-4C alkyl and alkoxy; R 2 , R 3 and R 4 are H, 1-4C alkoxy or alkyl or halo and R 5 is 1-2C alkyl or phenyl, or a salt thereof and a suitable excipient. Other pharmaceuticals which may be present are aspirin, N-acetyl-paminophenol, phenacetine, pyrazoline antipyretics, ethoxybenzamide or purine derivatives e.g. caffeine.
GB5972371A 1970-12-23 1971-12-22 1-vinylcarbonyl-piperazine derivatives having an analgesic action and process for preparing them Expired GB1359009A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19702063384 DE2063384A1 (en) 1970-12-23 1970-12-23 1- (1,2-Diphenyl-2-formylvinyl) -4methylpiperazine and its physiologically acceptable salts and process for its preparation
DE2160235A DE2160235A1 (en) 1971-12-04 1971-12-04 ANALGETICALLY EFFECTIVE 1-VINYL CARBONYL PIPERAZINE DERIVATIVES AND THE PROCESS FOR THEIR PRODUCTION

Publications (1)

Publication Number Publication Date
GB1359009A true GB1359009A (en) 1974-07-03

Family

ID=25760226

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5972371A Expired GB1359009A (en) 1970-12-23 1971-12-22 1-vinylcarbonyl-piperazine derivatives having an analgesic action and process for preparing them

Country Status (13)

Country Link
AT (1) AT321306B (en)
AU (1) AU464778B2 (en)
CA (1) CA971173A (en)
CH (1) CH575937A5 (en)
DD (2) DD102301A5 (en)
FR (1) FR2119052B1 (en)
GB (1) GB1359009A (en)
HU (1) HU163714B (en)
IL (1) IL38415A (en)
NL (1) NL7117365A (en)
NO (1) NO133232C (en)
PL (1) PL82643B1 (en)
SE (1) SE376608B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4182730A (en) * 1977-11-25 1980-01-08 Givaudan Corporation Process for the preparation of substituted dihydrocinnamaldehydes via novel β-chlorocinnamaldehydes

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE944852C (en) * 1949-11-30 1956-06-28 Basf Ag Process for the preparation of derivatives of 3-amino-acrolein

Also Published As

Publication number Publication date
CA971173A (en) 1975-07-15
FR2119052B1 (en) 1975-03-14
HU163714B (en) 1973-10-27
PL82643B1 (en) 1975-10-31
DD97202A5 (en) 1973-04-20
IL38415A (en) 1975-05-22
NL7117365A (en) 1972-06-27
AU464778B2 (en) 1975-09-04
IL38415A0 (en) 1972-02-29
FR2119052A1 (en) 1972-08-04
DD102301A5 (en) 1973-12-12
NO133232B (en) 1975-12-22
CH575937A5 (en) 1976-05-31
AU3715471A (en) 1973-06-28
NO133232C (en) 1976-03-31
SE376608B (en) 1975-06-02
AT321306B (en) 1975-03-25

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee