GB1359009A - 1-vinylcarbonyl-piperazine derivatives having an analgesic action and process for preparing them - Google Patents
1-vinylcarbonyl-piperazine derivatives having an analgesic action and process for preparing themInfo
- Publication number
- GB1359009A GB1359009A GB5972371A GB5972371A GB1359009A GB 1359009 A GB1359009 A GB 1359009A GB 5972371 A GB5972371 A GB 5972371A GB 5972371 A GB5972371 A GB 5972371A GB 1359009 A GB1359009 A GB 1359009A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- dec
- vinylcarbonyl
- preparing
- piperazine derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
- C07C47/24—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
- C07C47/277—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pile Receivers (AREA)
Abstract
1359009 Analgesics FARBWERKE HOECHST AG 22 Dec 1971 [23 Dec 1970 4 Dec 1971] 59723/71 Heading A5B [Also in Division C2] Pharmaceutical compositions for oral or parenteral administration as analgesics comprise a compound I in which R 1 is H, 1-4C alkyl, or phenyl optionally substituted by one or two of halo and 1-4C alkyl and alkoxy; R 2 , R 3 and R 4 are H, 1-4C alkoxy or alkyl or halo and R 5 is 1-2C alkyl or phenyl, or a salt thereof and a suitable excipient. Other pharmaceuticals which may be present are aspirin, N-acetyl-paminophenol, phenacetine, pyrazoline antipyretics, ethoxybenzamide or purine derivatives e.g. caffeine.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19702063384 DE2063384A1 (en) | 1970-12-23 | 1970-12-23 | 1- (1,2-Diphenyl-2-formylvinyl) -4methylpiperazine and its physiologically acceptable salts and process for its preparation |
DE2160235A DE2160235A1 (en) | 1971-12-04 | 1971-12-04 | ANALGETICALLY EFFECTIVE 1-VINYL CARBONYL PIPERAZINE DERIVATIVES AND THE PROCESS FOR THEIR PRODUCTION |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1359009A true GB1359009A (en) | 1974-07-03 |
Family
ID=25760226
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB5972371A Expired GB1359009A (en) | 1970-12-23 | 1971-12-22 | 1-vinylcarbonyl-piperazine derivatives having an analgesic action and process for preparing them |
Country Status (13)
Country | Link |
---|---|
AT (1) | AT321306B (en) |
AU (1) | AU464778B2 (en) |
CA (1) | CA971173A (en) |
CH (1) | CH575937A5 (en) |
DD (2) | DD102301A5 (en) |
FR (1) | FR2119052B1 (en) |
GB (1) | GB1359009A (en) |
HU (1) | HU163714B (en) |
IL (1) | IL38415A (en) |
NL (1) | NL7117365A (en) |
NO (1) | NO133232C (en) |
PL (1) | PL82643B1 (en) |
SE (1) | SE376608B (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4182730A (en) * | 1977-11-25 | 1980-01-08 | Givaudan Corporation | Process for the preparation of substituted dihydrocinnamaldehydes via novel β-chlorocinnamaldehydes |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE944852C (en) * | 1949-11-30 | 1956-06-28 | Basf Ag | Process for the preparation of derivatives of 3-amino-acrolein |
-
1971
- 1971-12-17 NL NL7117365A patent/NL7117365A/xx unknown
- 1971-12-20 CH CH1859571A patent/CH575937A5/xx not_active IP Right Cessation
- 1971-12-20 CA CA130,489A patent/CA971173A/en not_active Expired
- 1971-12-21 AU AU37154/71A patent/AU464778B2/en not_active Expired
- 1971-12-21 IL IL38415A patent/IL38415A/en unknown
- 1971-12-22 GB GB5972371A patent/GB1359009A/en not_active Expired
- 1971-12-22 DD DD166617A patent/DD102301A5/xx unknown
- 1971-12-22 DD DD159818A patent/DD97202A5/xx unknown
- 1971-12-22 AT AT1103171A patent/AT321306B/en not_active IP Right Cessation
- 1971-12-22 PL PL1971152415A patent/PL82643B1/pl unknown
- 1971-12-23 SE SE7116571A patent/SE376608B/xx unknown
- 1971-12-23 FR FR7146368A patent/FR2119052B1/fr not_active Expired
- 1971-12-23 HU HUHO1444A patent/HU163714B/hu unknown
- 1971-12-23 NO NO4820/71A patent/NO133232C/no unknown
Also Published As
Publication number | Publication date |
---|---|
CA971173A (en) | 1975-07-15 |
FR2119052B1 (en) | 1975-03-14 |
HU163714B (en) | 1973-10-27 |
PL82643B1 (en) | 1975-10-31 |
DD97202A5 (en) | 1973-04-20 |
IL38415A (en) | 1975-05-22 |
NL7117365A (en) | 1972-06-27 |
AU464778B2 (en) | 1975-09-04 |
IL38415A0 (en) | 1972-02-29 |
FR2119052A1 (en) | 1972-08-04 |
DD102301A5 (en) | 1973-12-12 |
NO133232B (en) | 1975-12-22 |
CH575937A5 (en) | 1976-05-31 |
AU3715471A (en) | 1973-06-28 |
NO133232C (en) | 1976-03-31 |
SE376608B (en) | 1975-06-02 |
AT321306B (en) | 1975-03-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PCNP | Patent ceased through non-payment of renewal fee |