GB1184649A - N-Substituted 2-Hydroxymorphinanes and Pharmaceutical Compositions containing them - Google Patents

N-Substituted 2-Hydroxymorphinanes and Pharmaceutical Compositions containing them

Info

Publication number
GB1184649A
GB1184649A GB903769A GB903769A GB1184649A GB 1184649 A GB1184649 A GB 1184649A GB 903769 A GB903769 A GB 903769A GB 903769 A GB903769 A GB 903769A GB 1184649 A GB1184649 A GB 1184649A
Authority
GB
United Kingdom
Prior art keywords
hydroxymorphinanes
substituted
pharmaceutical compositions
formula
cyclohexen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB903769A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Boehringer Ingelheim GmbH
Original Assignee
CH Boehringer Sohn AG and Co KG
Boehringer Ingelheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG, Boehringer Ingelheim GmbH filed Critical CH Boehringer Sohn AG and Co KG
Publication of GB1184649A publication Critical patent/GB1184649A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients

Abstract

1,184,649. N-substituted-3-hydroxymorphinanes. BOEHRINGER INGELHEIM G.m.b.H. 19 Feb., 1969 [19 Feb., 1968], No. 9037/69. Heading C2C. Novel compounds of the formula where Z represents a cyclohexen-2-yl or cyclohexen-1-ylmethyl group, and acid addition salts thereof, are obtained by reacting (-)-3-hydroxymorphinane with a compound of formula Z-Hal (where Hal is a halogen atom), and optionally converting the product into an acid addition salt. Pharmaceutical compositions, having analgesic activity with a morphine-antagonistic action, comprise at least one compound of the above formula in association with a pharmaceutical carrier or excipient, in a form suitable for oral, rectal or parenteral administration.
GB903769A 1968-02-19 1969-02-19 N-Substituted 2-Hydroxymorphinanes and Pharmaceutical Compositions containing them Expired GB1184649A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1670318 1968-02-19

Publications (1)

Publication Number Publication Date
GB1184649A true GB1184649A (en) 1970-03-18

Family

ID=5686318

Family Applications (1)

Application Number Title Priority Date Filing Date
GB903769A Expired GB1184649A (en) 1968-02-19 1969-02-19 N-Substituted 2-Hydroxymorphinanes and Pharmaceutical Compositions containing them

Country Status (4)

Country Link
BE (1) BE728660A (en)
ES (1) ES363742A1 (en)
FR (1) FR2002201A1 (en)
GB (1) GB1184649A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110290792A (en) * 2017-01-05 2019-09-27 景凯生物科技股份有限公司 Morphinan derivative and its composition for being used to treat autoimmunity, inflammation or the relevant obstacle of infection

Also Published As

Publication number Publication date
ES363742A1 (en) 1970-12-16
FR2002201A1 (en) 1969-10-17
BE728660A (en) 1969-08-19

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Legal Events

Date Code Title Description
PS Patent sealed
PLNP Patent lapsed through nonpayment of renewal fees