GB1309948A - Benzodiazepine derivatives processes for producing them and compo sitions containing them - Google Patents
Benzodiazepine derivatives processes for producing them and compo sitions containing themInfo
- Publication number
- GB1309948A GB1309948A GB2082771A GB2082771A GB1309948A GB 1309948 A GB1309948 A GB 1309948A GB 2082771 A GB2082771 A GB 2082771A GB 2082771 A GB2082771 A GB 2082771A GB 1309948 A GB1309948 A GB 1309948A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compound
- formula
- alkyl
- producing
- feb
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
- C07D243/26—Preparation from compounds already containing the benzodiazepine skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
- C07D243/28—Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
- C07D243/30—Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
- C07D243/30—Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings
- C07D243/36—Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings containing an indole or hydrogenated indole ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP969170A JPS4910954B1 (enrdf_load_stackoverflow) | 1970-02-03 | 1970-02-03 | |
| JP1053370A JPS4834600B1 (enrdf_load_stackoverflow) | 1970-02-05 | 1970-02-05 | |
| JP5552970A JPS4831118B1 (enrdf_load_stackoverflow) | 1970-06-24 | 1970-06-24 | |
| JP5553070A JPS4831119B1 (enrdf_load_stackoverflow) | 1970-06-24 | 1970-06-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1309948A true GB1309948A (en) | 1973-03-14 |
Family
ID=27455232
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2082771A Expired GB1309948A (en) | 1970-02-03 | 1971-04-19 | Benzodiazepine derivatives processes for producing them and compo sitions containing them |
Country Status (13)
-
1971
- 1971-01-06 CH CH1648473A patent/CH549033A/xx not_active IP Right Cessation
- 1971-01-27 DK DK35571AA patent/DK134018B/da not_active IP Right Cessation
- 1971-01-28 FI FI710234A patent/FI52081C/fi active
- 1971-01-28 NO NO300/71A patent/NO131031C/no unknown
- 1971-01-29 FR FR7103060A patent/FR2081482B1/fr not_active Expired
- 1971-02-01 DE DE19712166473 patent/DE2166473A1/de active Pending
- 1971-02-01 CH CH1089574A patent/CH581632A5/xx not_active IP Right Cessation
- 1971-02-01 CH CH144371A patent/CH578543A5/xx not_active IP Right Cessation
- 1971-02-02 BE BE762404A patent/BE762404A/xx not_active IP Right Cessation
- 1971-02-02 CA CA104,284A patent/CA970368A/en not_active Expired
- 1971-02-02 NL NLAANVRAGE7101382,A patent/NL169072C/xx not_active IP Right Cessation
- 1971-02-02 PL PL1971145964A patent/PL70900B1/pl unknown
- 1971-02-02 IL IL36121A patent/IL36121A/xx unknown
- 1971-02-02 SE SE01297/71A patent/SE364714B/xx unknown
- 1971-04-19 GB GB2082771A patent/GB1309948A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FI52081C (fi) | 1977-06-10 |
| IL36121A (en) | 1975-08-31 |
| NL169072C (nl) | 1982-06-01 |
| NL169072B (nl) | 1982-01-04 |
| PL70900B1 (en) | 1974-04-30 |
| FI52081B (enrdf_load_stackoverflow) | 1977-02-28 |
| IL36121A0 (en) | 1971-04-28 |
| DK134018B (da) | 1976-08-30 |
| DK134018C (enrdf_load_stackoverflow) | 1977-01-31 |
| DE2104571A1 (de) | 1971-08-05 |
| SE364714B (enrdf_load_stackoverflow) | 1974-03-04 |
| FR2081482B1 (enrdf_load_stackoverflow) | 1975-10-10 |
| NL7101382A (enrdf_load_stackoverflow) | 1971-08-05 |
| BE762404A (fr) | 1971-07-16 |
| CH578543A5 (enrdf_load_stackoverflow) | 1976-08-13 |
| DE2104571B2 (de) | 1976-03-04 |
| NO131031B (enrdf_load_stackoverflow) | 1974-12-16 |
| DE2166473A1 (de) | 1974-02-21 |
| CA970368A (en) | 1975-07-01 |
| NO131031C (enrdf_load_stackoverflow) | 1975-03-25 |
| FR2081482A1 (enrdf_load_stackoverflow) | 1971-12-03 |
| CH549033A (de) | 1974-05-15 |
| CH581632A5 (enrdf_load_stackoverflow) | 1976-11-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |