GB1327930A - 1,4-benzodiazepine derivatives - Google Patents
1,4-benzodiazepine derivativesInfo
- Publication number
- GB1327930A GB1327930A GB3864171A GB3864171A GB1327930A GB 1327930 A GB1327930 A GB 1327930A GB 3864171 A GB3864171 A GB 3864171A GB 3864171 A GB3864171 A GB 3864171A GB 1327930 A GB1327930 A GB 1327930A
- Authority
- GB
- United Kingdom
- Prior art keywords
- aug
- reacting
- benzodiazepine derivatives
- compounds
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
1327930 Benzodiazepines SIPHAR SA 17 Aug 1971 [24 Aug 1970] 38641/71 Heading C2C Compounds of the general formula (R 1 = H, C 1-4 alkyl; R 2,3 = H, C 1-4 alkyl optionally amino or OH-substituted, cycloalkyl or NR 2 R 3 = saturated heterocyclic group) are prepared by reacting the corresponding 3-hydroxybenzodiazepine with phenyl chloroformate and reacting the resulting 3-phenoxycarbonyloxybenzodiazepine with R 2 R 3 NH. The above compounds are tranquillizers and anxiolytics and may be administered in the form of pharmaceutical preparations containing them, with or without other active ingredients, in association with a carrier. Reference has been directed by the Comptroller to Specifications 1,022,642, 1,022,644 and 1,022,645.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1262070A CH538489A (en) | 1970-08-24 | 1970-08-24 | Process for the manufacture of 1,4-benzodiazepine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1327930A true GB1327930A (en) | 1973-08-22 |
Family
ID=4384789
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3864171A Expired GB1327930A (en) | 1970-08-24 | 1971-08-17 | 1,4-benzodiazepine derivatives |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS505718B1 (en) |
| BE (1) | BE830394Q (en) |
| BR (1) | BR7105511D0 (en) |
| CH (1) | CH538489A (en) |
| DK (1) | DK137754B (en) |
| ES (1) | ES394484A1 (en) |
| FR (1) | FR2103475B1 (en) |
| GB (1) | GB1327930A (en) |
| SE (1) | SE411625B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS52144693U (en) * | 1976-04-26 | 1977-11-02 | ||
| IT1165588B (en) * | 1983-03-23 | 1987-04-22 | Medosan Ind Biochimi | 1,4 THERAPEUTICALLY ACTIVE BENZODIAZEPINES |
| JPS644130U (en) * | 1987-06-25 | 1989-01-11 | ||
| JPH05192231A (en) * | 1992-05-22 | 1993-08-03 | Hokuei Kogyo Kk | Cart mechanism and hanger-housing implement for supporting housing implement |
-
1970
- 1970-08-24 CH CH1262070A patent/CH538489A/en not_active IP Right Cessation
-
1971
- 1971-08-17 GB GB3864171A patent/GB1327930A/en not_active Expired
- 1971-08-23 DK DK411971A patent/DK137754B/en not_active IP Right Cessation
- 1971-08-24 ES ES394484A patent/ES394484A1/en not_active Expired
- 1971-08-24 BR BR551171A patent/BR7105511D0/en unknown
- 1971-08-24 FR FR7130699A patent/FR2103475B1/fr not_active Expired
- 1971-08-24 JP JP6405971A patent/JPS505718B1/ja active Pending
- 1971-08-24 SE SE1073771A patent/SE411625B/en unknown
-
1975
- 1975-06-18 BE BE157468A patent/BE830394Q/en active
Also Published As
| Publication number | Publication date |
|---|---|
| FR2103475B1 (en) | 1974-10-18 |
| BR7105511D0 (en) | 1973-03-08 |
| CH538489A (en) | 1973-06-30 |
| SE411625B (en) | 1980-01-21 |
| DE2142181A1 (en) | 1972-03-02 |
| JPS505718B1 (en) | 1975-03-06 |
| DK137754C (en) | 1978-10-09 |
| FR2103475A1 (en) | 1972-04-14 |
| BE830394Q (en) | 1975-10-16 |
| ES394484A1 (en) | 1974-02-16 |
| DE2142181B2 (en) | 1976-05-06 |
| DK137754B (en) | 1978-05-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |