ES376793A2 - Novel n-substituted amines and their process of preparation - Google Patents
Novel n-substituted amines and their process of preparationInfo
- Publication number
- ES376793A2 ES376793A2 ES376793A ES376793A ES376793A2 ES 376793 A2 ES376793 A2 ES 376793A2 ES 376793 A ES376793 A ES 376793A ES 376793 A ES376793 A ES 376793A ES 376793 A2 ES376793 A2 ES 376793A2
- Authority
- ES
- Spain
- Prior art keywords
- novel
- preparation
- substituted amines
- nr1r11
- hypotensives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
Abstract
Novel compounds I: in which R1 and R11 are H or 2-3 C alkyl or NR1R11 is a heterocyclic ring, are prepared by reduction of the corresponding amides. Pharmaceutical compositions for oral administration as diuretics, hypotensives and spasmolytics comprise a compound I together with a suitable carrier.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR6909226A FR2035785A6 (en) | 1969-03-28 | 1969-03-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES376793A2 true ES376793A2 (en) | 1972-06-01 |
Family
ID=9031435
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES376793A Expired ES376793A2 (en) | 1969-03-28 | 1970-02-21 | Novel n-substituted amines and their process of preparation |
Country Status (7)
Country | Link |
---|---|
BE (1) | BE746287R (en) |
CH (1) | CH506476A (en) |
DE (1) | DE2006433A1 (en) |
ES (1) | ES376793A2 (en) |
FR (1) | FR2035785A6 (en) |
GB (1) | GB1243955A (en) |
NL (1) | NL7002398A (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7419980B2 (en) * | 2003-10-14 | 2008-09-02 | Wyeth | Fused-aryl and heteroaryl derivatives and methods of their use |
US7491723B2 (en) * | 2003-10-14 | 2009-02-17 | Wyeth | Alkanol and cycloalkanol-amine derivatives and methods of their use |
US7524846B2 (en) * | 2003-10-14 | 2009-04-28 | Wyeth | Arylalkyl- and cycloalkylalkyl-piperazine derivatives and methods of their use |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1178400A (en) * | 1966-12-13 | 1970-01-21 | Delalande Sa | Nitrogen Substituted Amines and their process of Preparation. |
-
1969
- 1969-03-28 FR FR6909226A patent/FR2035785A6/fr not_active Expired
-
1970
- 1970-02-02 GB GB482170A patent/GB1243955A/en not_active Expired
- 1970-02-12 DE DE19702006433 patent/DE2006433A1/en active Pending
- 1970-02-20 CH CH250570A patent/CH506476A/en unknown
- 1970-02-20 NL NL7002398A patent/NL7002398A/xx unknown
- 1970-02-20 BE BE746287D patent/BE746287R/en active
- 1970-02-21 ES ES376793A patent/ES376793A2/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
BE746287R (en) | 1970-08-20 |
GB1243955A (en) | 1971-08-25 |
DE2006433A1 (en) | 1970-10-01 |
NL7002398A (en) | 1970-09-30 |
FR2035785A6 (en) | 1970-12-24 |
CH506476A (en) | 1971-04-30 |
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