JPS4834600B1 - - Google Patents

Info

Publication number
JPS4834600B1
JPS4834600B1 JP1053370A JP1053370A JPS4834600B1 JP S4834600 B1 JPS4834600 B1 JP S4834600B1 JP 1053370 A JP1053370 A JP 1053370A JP 1053370 A JP1053370 A JP 1053370A JP S4834600 B1 JPS4834600 B1 JP S4834600B1
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP1053370A
Other languages
Japanese (ja)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to JP1053370A priority Critical patent/JPS4834600B1/ja
Priority to CH1648473A priority patent/CH549033A/xx
Priority to HUSU000589 priority patent/HU162329B/hu
Priority to DK35571AA priority patent/DK134018B/da
Priority to FI710234A priority patent/FI52081C/fi
Priority to NO300/71A priority patent/NO131031C/no
Priority to AT352572A priority patent/AT306040B/de
Priority to US111141A priority patent/US3867372A/en
Priority to FR7103060A priority patent/FR2081482B1/fr
Priority to CH144371A priority patent/CH578543A5/xx
Priority to CS426371A priority patent/CS179396B2/cs
Priority to CH1089474A priority patent/CH581631A5/xx
Priority to DE19712166473 priority patent/DE2166473A1/de
Priority to DE19712166472 priority patent/DE2166472A1/de
Priority to CH1089574A priority patent/CH581632A5/xx
Priority to DE19712104571 priority patent/DE2104571C3/de
Priority to BE762404A priority patent/BE762404A/xx
Priority to ES387878A priority patent/ES387878A1/es
Priority to PL1971145964A priority patent/PL70900B1/pl
Priority to SE01297/71A priority patent/SE364714B/xx
Priority to CA104,284A priority patent/CA970368A/en
Priority to PL18373971A priority patent/PL92568B1/pl
Priority to NLAANVRAGE7101382,A priority patent/NL169072C/xx
Priority to IL36121A priority patent/IL36121A/xx
Priority to GB2082771A priority patent/GB1309948A/en
Publication of JPS4834600B1 publication Critical patent/JPS4834600B1/ja
Priority to US05/497,936 priority patent/US4010154A/en
Priority to US05/710,665 priority patent/US4079053A/en
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/26Preparation from compounds already containing the benzodiazepine skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/28Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/30Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/30Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings
    • C07D243/36Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings containing an indole or hydrogenated indole ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP1053370A 1970-02-03 1970-02-05 Pending JPS4834600B1 (enrdf_load_stackoverflow)

Priority Applications (27)

Application Number Priority Date Filing Date Title
JP1053370A JPS4834600B1 (enrdf_load_stackoverflow) 1970-02-05 1970-02-05
CH1648473A CH549033A (de) 1970-02-03 1971-01-06 Verfahren zur herstellung von neuen benzodiazepinderivaten.
HUSU000589 HU162329B (enrdf_load_stackoverflow) 1970-02-03 1971-01-27
DK35571AA DK134018B (da) 1970-02-03 1971-01-27 Analogifremgangsmåde til fremstilling af 1-substituerede 1,4-benzodiazepinderivater eller salte deraf.
FI710234A FI52081C (fi) 1970-02-03 1971-01-28 Menetelmä terapeuttisesti käyttökelpoisten 1-substituoitujen 1,3-dihyd ro-2H-1,4-bentsodiatsepiini-2-onien valmistamiseksi.
NO300/71A NO131031C (enrdf_load_stackoverflow) 1970-02-03 1971-01-28
AT352572A AT306040B (de) 1970-02-05 1971-01-28 Verfahren zur Herstellung von neuen Benzodiazepinen und ihren Salzen mit Säuren
US111141A US3867372A (en) 1970-02-03 1971-01-29 Benzodiazepine process
FR7103060A FR2081482B1 (enrdf_load_stackoverflow) 1970-02-03 1971-01-29
DE19712166472 DE2166472A1 (de) 1970-02-05 1971-02-01 Verfahren zur herstellung von 1,3dihydro-2h-1,4-benzodiazepin-2-onen
CS426371A CS179396B2 (en) 1970-02-05 1971-02-01 Method for production of new derivatives of 1-substituted benzodiazepine.
CH1089474A CH581631A5 (enrdf_load_stackoverflow) 1970-02-05 1971-02-01
DE19712166473 DE2166473A1 (de) 1970-02-03 1971-02-01 Verfahren zur herstellung von 1,3dihydro-2h-1,4-benzodiazepin-2-onen
CH144371A CH578543A5 (enrdf_load_stackoverflow) 1970-02-03 1971-02-01
CH1089574A CH581632A5 (enrdf_load_stackoverflow) 1970-02-03 1971-02-01
DE19712104571 DE2104571C3 (de) 1970-02-03 1971-02-01 S-Phenyl-1,3-dihydro-2H-1,4benzodiazepin-2-one, ihre Salze und diese Verbindungen enthaltende Arzneipräparate
PL1971145964A PL70900B1 (en) 1970-02-03 1971-02-02 Benzodiazepine derivatives processes for producing them and compo sitions containing them[gb1309948a]
ES387878A ES387878A1 (es) 1970-02-03 1971-02-02 Un procedimiento para derivados de benzodiazepina y sales de los mismos.
BE762404A BE762404A (fr) 1970-02-03 1971-02-02 Nouveaux derives de la benzodiazepine
SE01297/71A SE364714B (enrdf_load_stackoverflow) 1970-02-03 1971-02-02
CA104,284A CA970368A (en) 1970-02-03 1971-02-02 Benzodiazepine derivatives
PL18373971A PL92568B1 (en) 1970-02-05 1971-02-02 1,4-benzodiazepine derivs - with alkylsulphon(in)ylalkyl substituent in 1-position[DE2166472A1]
NLAANVRAGE7101382,A NL169072C (nl) 1970-02-03 1971-02-02 Werkwijze voor het bereiden van 5-fenyl-7-halogeen-1,3-dihydro-2h-1,4-benzodiazepine-2-on-derivaten en zouten ervan, alsmede werkwijze ter bereiding van farmaceutische preparaten op basis van de aldus verkregen benzodiazepinederivaten.
IL36121A IL36121A (en) 1970-02-03 1971-02-02 Benzodiazepine derivatives and salts thereof,process for their preparation and pharmaceutical compositions containing the same
GB2082771A GB1309948A (en) 1970-02-03 1971-04-19 Benzodiazepine derivatives processes for producing them and compo sitions containing them
US05/497,936 US4010154A (en) 1970-02-03 1974-08-16 Benzodiazepinones
US05/710,665 US4079053A (en) 1970-02-03 1976-08-02 Benzodiazepine derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1053370A JPS4834600B1 (enrdf_load_stackoverflow) 1970-02-05 1970-02-05

Publications (1)

Publication Number Publication Date
JPS4834600B1 true JPS4834600B1 (enrdf_load_stackoverflow) 1973-10-22

Family

ID=11752885

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1053370A Pending JPS4834600B1 (enrdf_load_stackoverflow) 1970-02-03 1970-02-05

Country Status (6)

Country Link
JP (1) JPS4834600B1 (enrdf_load_stackoverflow)
AT (1) AT306040B (enrdf_load_stackoverflow)
CH (1) CH581631A5 (enrdf_load_stackoverflow)
CS (1) CS179396B2 (enrdf_load_stackoverflow)
DE (1) DE2166472A1 (enrdf_load_stackoverflow)
PL (1) PL92568B1 (enrdf_load_stackoverflow)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5518035U (enrdf_load_stackoverflow) * 1978-07-21 1980-02-05
JPS59112697U (ja) * 1983-01-20 1984-07-30 有限会社シオン 予定表示部材

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5518035U (enrdf_load_stackoverflow) * 1978-07-21 1980-02-05
JPS59112697U (ja) * 1983-01-20 1984-07-30 有限会社シオン 予定表示部材

Also Published As

Publication number Publication date
PL92568B1 (en) 1977-04-30
CS179396B2 (en) 1977-10-31
AT306040B (de) 1973-03-26
CH581631A5 (enrdf_load_stackoverflow) 1976-11-15
DE2166472A1 (de) 1974-02-21

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